scholarly journals The effects of feeding toxic groundnut meal to growing pigs and its interaction with high-copper diets

1968 ◽  
Vol 22 (4) ◽  
pp. 535-554 ◽  
Author(s):  
R. S. Barber ◽  
R. Braude ◽  
K. G. Mitchell ◽  
J. D. J. Harding ◽  
G. Lewis ◽  
...  
Keyword(s):  
Serum Alkaline Phosphatase ◽  
Clinical Signs ◽  
Live Weight ◽  
Liver Weight ◽  
Growing Pigs ◽  
Feed Conversion ◽  
Large White ◽  
Loss Of Appetite ◽  
Aflatoxin B ◽  
Histological Results

1. Three experiments using sixty individually fed, enzootic pneumonia-free Large White pigs on experiment from 9–11 weeks of age to 200 lb live weight are described.2. Information was obtained on the effect of different dietary concentrations of aflatoxin B1 on the performance of the pigs, on various biochemical measurements and on the histology of the livers and kidneys.3. Reduced growth rate and loss of appetite were the main adverse effects observed, their extent being positively related to the dietary level of aflatoxin B1. No marked clinical signs were seen, mortality was very low and there was little or no effect on the feed conversion efficiency of the animals.4. No evidence for any adverse interaction between aflatoxin B1 and the presence in the diet of a supplement of copper sulphate providing 250 ppm Cu was apparent from either the performance, biochemical or histological results obtained. It was concluded that the few isolated reports of toxicity in growing pigs fed diets containing a supplement of 250 ppm Cu were unlikely to have been the result of the unsuspected presence of aflatoxin B1 in the feedingstuffs used in the diets.5. Aflatoxin B1 tended to increase the serum alkaline phosphatase level, the concentration of Cu in the kidneys, and liver weight and to reduce the liver vitamin A concentration. No other consistent differences in the measurements made were observed.6. The extent of the total pathological abnormality observed in the livers and kidneys was closely related to the level of aflatoxin B1 in the diet.

Influence of energy and protein concentration in the diet on the performance of growing pigs 2. Differing nutrient density at a constant energy: protein ratio

1972 ◽  
Vol 14 (1) ◽  
pp. 47-55 ◽  
Author(s):  
G. A. Lodge ◽  
M. E. Cundy ◽  
R. Cooke ◽  
D. Lewis
Keyword(s):  
Growth Rate ◽  
Live Weight ◽  
Fat Content ◽  
Growing Pigs ◽  
Feed Conversion ◽  
Large White ◽  
Protein Ratio ◽  
Treatment Groups ◽  
Nutrient Density ◽  
Amino Acid Balance

SUMMARYForty-eight gilts by Landrace sires on Large White × Landrace females were randomly allocated to eight pens and within pens to six treatment groups involving three diets and two levels of feeding from 23 to 59 kg live weight. All diets were formulated to have approximately the same ratio of digestible energy to crude protein (160 kcal DE/unit % CP) but different energy and protein concentrations: (A) 3500 kcal/kg DE and 21 % CP, (B) 3150 kcal/kg DE and 19% CP, and (C) 2800 kcal/kg DE and 17% CP. Amino acid balance was maintained relatively constant with synthetic lysine, methionine and tryptophan. The levels of feeding were such that the lower level of diet A allowed an intake of energy and protein similar to the higher level of diet B, and the lower level of B was similar to the higher level of C.On the lower level of feeding, growth rate, efficiency of feed conversion and carcass fat content increased linearly with each increment in nutrient concentration; on the higher level of feeding growth rate and EFC increased from diet C to B but not from B to A, whereas carcass fat content increased linearly with diet from the lowest to the highest concentration. There was a non-significant tendency for the higher density diets at a similar level of nutrient intake to give better EFC and fatter carcasses than the lower density diets.

The use of moist barley in diets for growing pigs

1970 ◽  
Vol 12 (4) ◽  
pp. 561-568 ◽  
Author(s):  
R. M. Livingstone ◽  
D. M. S. Livingston
Keyword(s):  
Dry Matter ◽  
Live Weight ◽  
Matter Content ◽  
Growing Pigs ◽  
Dry Matter Content ◽  
Feed Conversion ◽  
High Moisture ◽  
Large White ◽  
Large White Breed ◽  
White Breed

SUMMARYA total of 156 pigs of the Large White breed were used in a series of four experiments to test the suitability of barley which had been stored with a high moisture content as an ingredient in the diets of growing pigs. Barleys with mean moisture contents of 26·3%, 28·1% and 21·2% and a range from 19·6% to 30·5%, from three successive harvests were used.In all the trials there was evidence that the use of moist barley in diets for growing pigs had an adverse effect on live-weight gain and feed conversion ratio, the effect being independent of whether feed intakes were equated on the basis of the dry-matter content of the diets. In one of the experiments performance was depressed to the extent of causing changes in carcass characteristics. The performance of pigs given rolled barley was similar to that of others given ground barley.

scholarly journals Growth Performance, Nutrient Digestibility and Carcass Characteristics of Pigs Fed Diets Containing Amarula (Sclerocarya Birrea A. Rich) Nut Cake as Replacement To Soybean Meal

2021 ◽  
Author(s):  
Maggy Palesa Mabena ◽  
Moses Ratsaka ◽  
Thobela Nkukwana ◽  
Ingrid Malebana ◽  
Douglas Nkosi
Keyword(s):  
Growth Performance ◽  
Feed Intake ◽  
Average Daily Gain ◽  
Carcass Characteristics ◽  
Live Weight ◽  
Nutrient Digestibility ◽  
Growing Pigs ◽  
Feed Conversion ◽  
Large White ◽  
Sclerocarya Birrea

Abstract This experiment evaluated varying levels of Amarula (Sclerocarya birrea A. Rich) nut cake (ANC) on growth performance, nutrient digestibility and carcass characteristics in pigs. Thirty Large White × Landrace (LW × LR) pigs were stratified by weight (average live weight of 20 ± 5 kg) and randomly allocated to the five experimental diets that contained 0 (control), 50, 100, 150 and 200 g ANC/kg DM. Each pig served as a replicate unit, housed individually. Bodyweight, feed intake, average daily gain (ADG) and feed conversion ratio (FCR) were recorded weekly throughout the trial period. On completion of the growth trial, following a 3-day adaptation, a nutrient digestibility study was conducted over 5 days. Thereafter, pigs were fasted for twelve hours, weighed, slaughtered, and carcass samples were collected for analysis. Feed intake was not affected by dietary treatment, but ADGs were reduced at ANC levels > 15%, resulting in poor FCR. Protein digestibility was reduced at ANC levels > 15%, while ether extract and fibre levels increased. Warm and cold carcass weights were lower at ANC levels > 15, with improved meat redness and lightness. It was concluded that ANC could replace SBM in the diet of growing pigs at less than 15% inclusion level.

Protein levels in diets for European pigs in the tropics. 1. The effect of methionine supplementation on the protein requirement of growing pigs

1975 ◽  
Vol 20 (1) ◽  
pp. 133-146 ◽  
Author(s):  
B. L. Fetuga ◽  
G. M. Babatunde ◽  
V. A. Oyenuga
Keyword(s):  
Protein Level ◽  
Nitrogen Retention ◽  
Live Weight ◽  
Growing Pigs ◽  
Feed Conversion ◽  
Large White ◽  
Dietary Nitrogen ◽  
Protein Levels ◽  
Weight Growth ◽  
Cystine Level

SUMMARYOne hundred and twenty-eight Landrace and Large White pigs were allocated on the basis of sex, litter origin and initial weight to one of 16 treatments, made up of four basal 16, 18, 20 and 22% protein diets, each supplemented with either 0·00, 0·10, 0·15 or 0·20% synthetic DL-methionine, at a common digestible energy level of 3740 kcal/kg. Pigs were reared between 8 and 50 kg live weight. Growth rate of pigs and efficiency of feed conversion were significantly improved as the protein levels were increased up to the 20% protein level, optimal performance being on the 20% protein diet, with added 0·15% methionine, giving a total methionine+cystine level of 0·65% and a lysine level of 1·07%. Addition of synthetic methionine to the diets resulted in significant improvement in the rate and efficiency of gain only at the 16 and 18% protein levels.Carcass leanness and fatness increased and decreased respectively over the whole range of protein levels. Graded addition of DL-methionine within each protein level did not influence carcass characteristics.Nitrogen retention showed optimal utilization of dietary nitrogen to be at the 18% protein level, with a total dietary methionine + cystine level of 0·61%, which was at variance with the levels indicated by both growth and feed efficiency.

Blood prolactin depression in growing pigs fed sorghum ergot (Claviceps africana)

2000 ◽  
Vol 51 (6) ◽  
pp. 785 ◽  
Author(s):  
B. J. Blaney ◽  
J. S. Kopinski ◽  
M. H. Magee ◽  
R. A. McKenzie ◽  
G. W. Blight ◽  
...  
Keyword(s):  
Feed Intake ◽  
Clinical Signs ◽  
Growing Pigs ◽  
Feed Consumption ◽  
Feed Conversion ◽  
Large White ◽  
Digestible Energy ◽  
Young Pigs ◽  
Claviceps Africana ◽  
Full Trial

The toxicity of sorghum ergot (Claviceps africana) was assessed in young pigs over 28 days. Forty-eight pigs of both sexes and 2 breeds (Large White and Duroc) were allocated across 6 grower diets, balanced for fibre and predicted digestible energy, and containing 0, 0.3, 0.6, 1.3, 2.5, or 5% ergot sclerotia [the 5% sclerotia diet contained 70 mg alkaloids/kg (>90% dihydroergosine)]. Blood samples taken on Days 0 and 28 were analysed for prolactin and clinical, biochemical, and haematological indices of health. Feed consumption and liveweight were individually monitored. There were no clinical signs of illness attributable to ergotism in the pigs. Blood prolactin concentrations were significantly depressed in pigs receiving 9 mg alkaloids/kg (0.6% sclerotia) and by >80% in pigs receiving 35 and 70 mg alkaloids/kg, clearly indicating a potential to interfere with lactation in sows. Reductions in feed intake and poor feed conversion were observed over the first 7 days with >9 mg alkaloids/kg, but some tolerance developed later. Feed refusal was more pronounced for pigs of the Duroc breed. Over the full trial period, growth was reduced by about 30% in pigs receiving 70 mg alkaloids/kg, as a result of poor feed intake and feed conversion. Digestible energy of diets containing ergot was later found to be lower than predicted, which contributed to this result.

Influence of energy and protein concentration in the diet on the performance of growing pigs 3. Response to differences in levels of both energy and protein

1972 ◽  
Vol 14 (2) ◽  
pp. 219-228 ◽  
Author(s):  
R. Cooke ◽  
G. A. Lodge ◽  
D. Lewis
Keyword(s):  
Dietary Protein ◽  
Energy Levels ◽  
Live Weight ◽  
Linear Increase ◽  
Growing Pigs ◽  
Percentage Increase ◽  
Feed Conversion ◽  
Fat Percentage ◽  
Large White ◽  
Protein Levels

SUMMARYOne hundred and twenty eight gilts by Landrace sires out of Large White × Landrace females were allocated on the basis of litter relation-ship and initial weight to 16 treatments involving the individual feeding of four dietary protein levels (approximately 15%, 18%, 21% and 24% CP) at each of four energy levels (2830, 3100, 3375 and 3585 kcal DE/kg air-dry feed). Amino acid balance (as% of total CP) was maintained relatively constant, using synthetic lysine and methionine where necessary. Growth performance was measured over a live-weight range of 23 kg to 59 kg, at which latter weight the pigs were slaughtered for carcass evaluation by dissection of the middle ‘joint’ from a half carcass. Linear carcass measure-ments were also taken. There was a significant energy × protein interaction only for killing-out percentage; for all other measures the main effects could be assessed independently. Increase in dietary energy value gave linear increase in growth rate (GR) and improve-ment in efficiency of feed conversion (EFC), accompanied by linear decrease in lean percentage and increase in fat percentage. Increase in dietary protein level gave an increase in GR and improvement in EFC with the first increment (from 15% to 18% CP), but depressions in both these characteristics with the final increment (from 21% to 24% CP). Lean percentage increased and fat percentage decreased with the first protein increment, with no further significant changes. Calculation of daily rates of tissue deposition indicated that maximum rate and efficiency of fat-free carcass gain could be attained with the second lowest energy and protein levels tested (i.e. 3106 kcal DE/kg and 18·2% CP).

Influence of energy and protein concentration in the diet on the performance of growing pigs 1. Response to protein intake on a high-energy diet

1972 ◽  
Vol 14 (1) ◽  
pp. 35-46 ◽  
Author(s):  
R. Cooke ◽  
G. A. Lodge ◽  
D. Lewis
Keyword(s):  
Dietary Protein ◽  
Full Range ◽  
Live Weight ◽  
High Energy ◽  
Growing Pigs ◽  
Feed Conversion ◽  
Large White ◽  
Protein Levels ◽  
The Individual ◽  
Amino Acid Balance

SUMMARYSixty gilts by Landrace sires out of Large White × Landrace females were allocated on the basis of litter relationship and initial weight to six treatments involving the individual feeding of six dietary protein levels, 15·5%, 17·4%, 20·2%, 22·3%, 25·3% and 27·3% crude protein (CP), at a common energy level of approximately 3500 kcal/kg DE, from 23 to 59 kg live weight. Amino acid balance was maintained relatively constant with synthetic lysine, methionine and tryptophan. There were significant increases in growth rate and efficiency of feed conversion from the 15·5% to the 17·4% CP diets and significant reductions in both from the 25·3 % to the 27·3 % CP diets. Carcass lean by dissection increased linearly (r = 0·976) and fat decreased linearly (r = −0·992) with dietary protein increment over the full range studied. As best growth performance and maximum lean content were attained at different dietary CP levels, a combined measure of daily lean deposition was calculated; this indicated that maximum rate of lean growth and efficiency of feed conversion to lean were reached on the 22·3% CP level. In terms of efficiency of utilization of nutrients, maximum retentions of both DE and DCP in the edible part of the carcass appeared to be attained on the two lowest dietary protein levels.

Subchronic Hepatotoxicity Evaluation of Hydrazobenzene in Fischer 344 Rats

2012 ◽  
Vol 31 (6) ◽  
pp. 564-571 ◽  
Author(s):  
Darol E. Dodd ◽  
Linda J. Pluta ◽  
Mark A. Sochaski ◽  
Henry G. Wall ◽  
Russell S. Thomas
Keyword(s):  
Body Weight ◽  
Serum Alkaline Phosphatase ◽  
Clinical Signs ◽  
Liver Weight ◽  
Fischer 344 ◽  
Liver Histopathology ◽  
Clinical Observations ◽  
Body Weights ◽  
Effect Level ◽  
F344 Rats

Male F344 rats were exposed to hydrazobenzene (HZB) by dietary feed at concentrations of 0, 5, 20, 80, 200, or 300 ppm for 5 days, 2 weeks, 4 weeks, or 13 weeks duration. End points evaluated included clinical observations, body weights, liver weights, serum chemistry, blood HZB, gross pathology, and liver histopathology. There were no HZB exposure-related clinical signs of toxicity. During study weeks 8 through 13, body weight means in rats of the 300 ppm group were 6% lower compared to control rat means. Serum alkaline phosphatase concentrations were decreased in rats of the 300 ppm group at all time points. Relative (to body weight) liver weight increases were observed in rats of the 200 and 300 ppm groups following 5 days (300 ppm only), 2 weeks, 4 weeks, and 13 weeks of exposure. Following 13 weeks of exposure, microscopic findings in the liver were observed only in rats of the 200 and 300 ppm groups and consisted of hypertrophy, macrovesiculation, eosinophilic granular cytoplasm, and bile duct duplication. Blood HZB concentrations ranged from 0.002 to 0.006 µg/mL in rats of the 200 or 300 ppm groups. A no observed effect level of 80 ppm (4.80 mg/kg per d) was selected based on the observation of microscopic hepatocyte alterations at ≥200 ppm HZB.

scholarly journals Copy number variation of amylase alpha 2B gene is associated with feed efficiency traits in Large White pigs--title not given--

2021 ◽  
Author(s):  
Tsukasa Yoshidomi ◽  
Kazuaki Tanaka ◽  
Tatsuya Takizawa ◽  
Satoshi Nikaido ◽  
Tetsuya Ito ◽  
...  
Keyword(s):  
Copy Number Variation ◽  
Feed Intake ◽  
Feed Efficiency ◽  
Copy Number ◽  
Conversion Ratio ◽  
Growing Pigs ◽  
Feed Conversion Ratio ◽  
Feed Conversion ◽  
Large White ◽  
Number Variation

Copy number variation (CNV) of the AMY gene in humans has been enthusiastically studied for its association with starch digestibility and obesity. The alpha-amylase (AMY) is a major starch digestive enzyme in mammals. This study aimed to determine the association between CNV of the porcine pancreatic amylase (AMY2B) gene and feed efficiency. Improvement of feed efficiency in growing pigs is of great economic interest. We assayed the copy number of AMY2B by using real-time quantitative PCR (qPCR) in a Large White pig population. We identified three genotypes for AMY2B CNVs, namely I/I (homozygotes of haplotype I; a chromosome with one copy of AMY2B), I/II (heterozygotes of haplotype I and II; a chromosome with two copies) and II/II (homozygotes of haplotype II). We tested the genotypes of the parental generation consisting of six males, 21 females and 265 offspring piglets to validate the AMY2B CNV genotyping. With very few mistyping exceptions, copy numbers of AMY2B were transmitted to piglets in segregation ratios following Mendelian inheritance. Finally, we performed an association analysis between the CNV of the AMY2B gene and feed efficiency traits in 207 uncastrated male pigs. The generalised linear model analysis showed the significant effects of AMY2B CNV genotype on average daily feed intake, total feed intake and feed conversion ratio during growth from 30 kg to 100 kg body weight. However, it was not associated with average daily gain, backfat thickness and loin eye muscle area. Individuals with the genotype I/I had about 76.6 ± 27.1 g lower average daily feed intake, 5.35 ± 1.90 kg lower total feed intake and 0.089 8 ± 0.026 5 lower feed conversion ratio than individuals with I/II and II/II genotypes. Thus, AMY2B CNV has the potential to be an effective genetic marker that could reduce feed costs for pig farming.  

scholarly journals Utilisation of reactive lysine from meat and bone meals of different ash content by growing-finishing pigs

1998 ◽  
Vol 7 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Kirsi Partanen ◽  
Hilkka Siljander-Rasi ◽  
Timo Alaviuhkola ◽  
Nina Van Gilse van der Pals
Keyword(s):  
Control Diet ◽  
Live Weight ◽  
Ash Content ◽  
Growing Pigs ◽  
Finishing Pigs ◽  
Meat And Bone Meal ◽  
Feed Conversion ◽  
Diet Formulation ◽  
Soyabean Meal ◽  
Feed Unit

A growth experiment was conducted using 50 pigs (25-100 kg) to evaluate the use of meat and bone meals of different ash content as a substitute for soyabean meal (SBM) for growing pigs and the potential of 1-fluoro-2,4-dinitrobenzene (FDNB) reactive lysine in diet formulation. The control diet consisted of barley and SBM. For test diets, either 33 or 67% of SBM was replaced with meat and bone meal of low (ML, 205 g ash/kg) or high (MH, 349 g ash/kg) ash content. SBM, ML33, ML67, MH33 and MH67 diets contained 7.8, 7.8, 8.2, 7.8 and 7.9 g FDNB-reactive lysine/feed unit (feed unit is equivalent to 9.3 MJ NE), respectively. For these diets, average daily live weight gains (ADG) were 859, 830, 805, 854 and 813 g/d with feed conversion ratios of 2.25, 2.40, 2.41, 2.31 and 2.44 feed units/kg, respectively. Pigs fed the SBM diet grew faster (P

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