Blood prolactin depression in growing pigs fed sorghum ergot (Claviceps africana)

2000 ◽  
Vol 51 (6) ◽  
pp. 785 ◽  
Author(s):  
B. J. Blaney ◽  
J. S. Kopinski ◽  
M. H. Magee ◽  
R. A. McKenzie ◽  
G. W. Blight ◽  
...  

The toxicity of sorghum ergot (Claviceps africana) was assessed in young pigs over 28 days. Forty-eight pigs of both sexes and 2 breeds (Large White and Duroc) were allocated across 6 grower diets, balanced for fibre and predicted digestible energy, and containing 0, 0.3, 0.6, 1.3, 2.5, or 5% ergot sclerotia [the 5% sclerotia diet contained 70 mg alkaloids/kg (>90% dihydroergosine)]. Blood samples taken on Days 0 and 28 were analysed for prolactin and clinical, biochemical, and haematological indices of health. Feed consumption and liveweight were individually monitored. There were no clinical signs of illness attributable to ergotism in the pigs. Blood prolactin concentrations were significantly depressed in pigs receiving 9 mg alkaloids/kg (0.6% sclerotia) and by >80% in pigs receiving 35 and 70 mg alkaloids/kg, clearly indicating a potential to interfere with lactation in sows. Reductions in feed intake and poor feed conversion were observed over the first 7 days with >9 mg alkaloids/kg, but some tolerance developed later. Feed refusal was more pronounced for pigs of the Duroc breed. Over the full trial period, growth was reduced by about 30% in pigs receiving 70 mg alkaloids/kg, as a result of poor feed intake and feed conversion. Digestible energy of diets containing ergot was later found to be lower than predicted, which contributed to this result.

Author(s):  
Tsukasa Yoshidomi ◽  
Kazuaki Tanaka ◽  
Tatsuya Takizawa ◽  
Satoshi Nikaido ◽  
Tetsuya Ito ◽  
...  

Copy number variation (CNV) of the AMY gene in humans has been enthusiastically studied for its association with starch digestibility and obesity. The alpha-amylase (AMY) is a major starch digestive enzyme in mammals. This study aimed to determine the association between CNV of the porcine pancreatic amylase (AMY2B) gene and feed efficiency. Improvement of feed efficiency in growing pigs is of great economic interest. We assayed the copy number of AMY2B by using real-time quantitative PCR (qPCR) in a Large White pig population. We identified three genotypes for AMY2B CNVs, namely I/I (homozygotes of haplotype I; a chromosome with one copy of AMY2B), I/II (heterozygotes of haplotype I and II; a chromosome with two copies) and II/II (homozygotes of haplotype II). We tested the genotypes of the parental generation consisting of six males, 21 females and 265 offspring piglets to validate the AMY2B CNV genotyping. With very few mistyping exceptions, copy numbers of AMY2B were transmitted to piglets in segregation ratios following Mendelian inheritance. Finally, we performed an association analysis between the CNV of the AMY2B gene and feed efficiency traits in 207 uncastrated male pigs. The generalised linear model analysis showed the significant effects of AMY2B CNV genotype on average daily feed intake, total feed intake and feed conversion ratio during growth from 30 kg to 100 kg body weight. However, it was not associated with average daily gain, backfat thickness and loin eye muscle area. Individuals with the genotype I/I had about 76.6 ± 27.1 g lower average daily feed intake, 5.35 ± 1.90 kg lower total feed intake and 0.089 8 ± 0.026 5 lower feed conversion ratio than individuals with I/II and II/II genotypes. Thus, AMY2B CNV has the potential to be an effective genetic marker that could reduce feed costs for pig farming.  


2020 ◽  
Vol 46 (4) ◽  
pp. 9-15
Author(s):  
A. A. Famakinwa ◽  
O. A. Adebiyi ◽  
T. O. Bankole ◽  
P. O. Idahosa

This study was carried out to determine the effect of object combination as environmental enrichment on behaviour of growing pigs. Thirty-six (36) crossbreed (Large White X Landrace) growing pigs with average weight of 34-36Kg were allotted randomly into four treatments, replicated three times in a completely randomized design. The four treatments were; Control (without enrichment), PRope (2 pieces of polyester rope), treatment SWood (2 pieces of soft wood) and treatment PRope+SWood (1 piece of soft wood and 1 piece of polyester rope). Behavioural observations were monitored by CCTV and recordings were made for 6 hours/day and 3days/week. At the end of the experiment, data collected includes average feed intake and average weight gain while feed conversion ratio was calculated. Likewise, behavioural observations; enrichment use, general activities, pen manipulation and pen-mate manipulation were observed. Behavioural data were analyzed using repeated measures analysis of variance (ANOVA) while performance data were analysed using one-way ANOVA. Performance data were significantly influenced (P<0.05) by enrichments for all the parameters measured. PRope+SWood had the highest value for the final weight (50.63kg), average weight gain (15.95kg) and average feed intake (56.61kg) while PRope had the highest FCR 4.18). Penmate manipulation (10.48%), pen manipulation (19.02%) and general activities (14.62%) were lower and significantly better for PRope+SWood compared to PRope and SWood and the highest interaction with enrichment objects was observed in the PRope+SWood (55.88%). It can be concluded that the use of combination of enrichment objects enhanced the performance and behaviour of pigs.


2021 ◽  
Author(s):  
Maggy Palesa Mabena ◽  
Moses Ratsaka ◽  
Thobela Nkukwana ◽  
Ingrid Malebana ◽  
Douglas Nkosi

Abstract This experiment evaluated varying levels of Amarula (Sclerocarya birrea A. Rich) nut cake (ANC) on growth performance, nutrient digestibility and carcass characteristics in pigs. Thirty Large White × Landrace (LW × LR) pigs were stratified by weight (average live weight of 20 ± 5 kg) and randomly allocated to the five experimental diets that contained 0 (control), 50, 100, 150 and 200 g ANC/kg DM. Each pig served as a replicate unit, housed individually. Bodyweight, feed intake, average daily gain (ADG) and feed conversion ratio (FCR) were recorded weekly throughout the trial period. On completion of the growth trial, following a 3-day adaptation, a nutrient digestibility study was conducted over 5 days. Thereafter, pigs were fasted for twelve hours, weighed, slaughtered, and carcass samples were collected for analysis. Feed intake was not affected by dietary treatment, but ADGs were reduced at ANC levels > 15%, resulting in poor FCR. Protein digestibility was reduced at ANC levels > 15%, while ether extract and fibre levels increased. Warm and cold carcass weights were lower at ANC levels > 15, with improved meat redness and lightness. It was concluded that ANC could replace SBM in the diet of growing pigs at less than 15% inclusion level.


1968 ◽  
Vol 22 (4) ◽  
pp. 535-554 ◽  
Author(s):  
R. S. Barber ◽  
R. Braude ◽  
K. G. Mitchell ◽  
J. D. J. Harding ◽  
G. Lewis ◽  
...  

1. Three experiments using sixty individually fed, enzootic pneumonia-free Large White pigs on experiment from 9–11 weeks of age to 200 lb live weight are described.2. Information was obtained on the effect of different dietary concentrations of aflatoxin B1 on the performance of the pigs, on various biochemical measurements and on the histology of the livers and kidneys.3. Reduced growth rate and loss of appetite were the main adverse effects observed, their extent being positively related to the dietary level of aflatoxin B1. No marked clinical signs were seen, mortality was very low and there was little or no effect on the feed conversion efficiency of the animals.4. No evidence for any adverse interaction between aflatoxin B1 and the presence in the diet of a supplement of copper sulphate providing 250 ppm Cu was apparent from either the performance, biochemical or histological results obtained. It was concluded that the few isolated reports of toxicity in growing pigs fed diets containing a supplement of 250 ppm Cu were unlikely to have been the result of the unsuspected presence of aflatoxin B1 in the feedingstuffs used in the diets.5. Aflatoxin B1 tended to increase the serum alkaline phosphatase level, the concentration of Cu in the kidneys, and liver weight and to reduce the liver vitamin A concentration. No other consistent differences in the measurements made were observed.6. The extent of the total pathological abnormality observed in the livers and kidneys was closely related to the level of aflatoxin B1 in the diet.


1978 ◽  
Vol 27 (3) ◽  
pp. 345-354 ◽  
Author(s):  
G. A. Lodge ◽  
D. Lister ◽  
J. D. Wood ◽  
M. S. Wolynetz

ABSTRACTIn an experiment which showed that the results of a genotype comparison are influenced by the design of the test, 16 castrated male and 16 female pigs of each of Large White (LW) and Gloucester Old Spot (GOS) breeds were allocated equally among four treat- ments: WW—rationed by weight and slaughtered by weight; A A—rationed by age and slaughtered by age; AW—rationed by age and slaughtered by weight; and WF—rationed by weight and slaughtered after a common total feed intake. The experiment was designed so that performance of LW would be similar on all treatments, and the degree to which the GOS differed from the LW on each of these treatments was then evaluated. All pigs started on the experiment at 12 weeks of age, at which time mean weight of the LW was 14% greater than the mean for the GOS. The only between- breed difference that was statistically significant (P<0·05) on all treatments was weight of lean. Average daily gain and efficiency of feed conversion were significantly different between breeds only on the WW treatment. Weight of fat was significantly different on WW and AW but not on AA or WF.


1963 ◽  
Vol 43 (2) ◽  
pp. 294-302 ◽  
Author(s):  
J. E. Troelsen ◽  
J. M. Bell

The relative feed intake, feed efficiency and carcass characteristics of growing pigs and mice were studied to determine the value of the mouse as a pilot animal in pig nutrition research. Fifteen rations were fed in two experiments to 120 pigs and 120 mice. They were composed of equal parts of wheat and barley, plus one of three levels each of oat hulls, alfalfa meal, wheat bran, cellulose, and corn-cob meal to produce mixtures containing an estimated 62, 65, and 68 per cent of total digestible nutrients. With pigs, data were obtained on feed and growth from 100 to 200 pounds live weight; carcass measurements were made on the slaughtered barrows at 200 pounds. Feed and growth records of mice were kept for 14 days commencing at weaning; the carcasses were then analysed for water, fat, protein and ash.The relative response of the two species is indicated by the following correlation coefficients: feed consumption (0.67); digestibility of dry matter (0.96); digestibility of energy (0.87); consumption of digestible energy (0.79); rate of gain (0.63), and per cent fat in mouse carcasses and back fat thickness in the barrows (0.70). The correlation between per cent fat in mouse carcasses and the R.O.P. score for barrows was −0.67.The mean ratio of swine and mice was 581:1 for physiological body weight (kg.0.75), 693:1 and 654:1 for consumption of dry matter, and digestible energy, respectively, reflecting a relatively greater feed capacity of pigs and a higher energy digestibility by mice. The corresponding ratios for the effects of changes in ration composition were 369:1, 331:1, and 462:1, indicating that the pigs were better equipped to cope with bulky rations. It was suggested that mice were more efficient in conversion of feed to body weight gain because in pigs a greater part of the gain was fat.


Animals ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 705 ◽  
Author(s):  
Chia ◽  
Tanga ◽  
Osuga ◽  
Alaru ◽  
Mwangi ◽  
...  

Pig production is one of the fastest growing livestock sectors. Development of this sector is hampered by rapidly increasing costs of fishmeal (FM), which is a common protein source in animal feeds. Here, we explored the potential of substituting FM with black soldier fly larval meal (BSFLM) on growth and blood parameters of pigs as well as economic aspects. At weaning, 40 hybrid pigs, i.e., crossbreeds of purebred Large White and Landrace were randomly assigned to five iso-nitrogenous and iso-energetic dietary treatments: Control (0% BSFLM and 100% FM (T0)), and FM replaced at 25% (T25), 50% (T50), 75% (T75) and 100% (T100) with BSFLM. Average daily feed intake (ADFI), average daily gain (ADG), body weight gain (BWG) and feed conversion ratio (FCR) were calculated for the whole trial. Hematological and serum biochemical parameters, the cost–benefit ratio (CBR) and return on investment (RoI) were evaluated. No significant effect of diet type was observed on feed intake and daily weight gain. Red or white blood cell indices did not differ among diets. Pigs fed T25, T75 and T100, had lower platelet counts compared to T0 and T50. Dietary inclusion of BSFLM did not affect blood total cholesterol, triglycerides, low-density lipoprotein and high-density lipoprotein. CBR and RoI were similar for the various diets. In conclusion, BSFLM is a suitable and cost-effective alternative to fishmeal in feed for growing pigs.


1988 ◽  
Vol 36 (1) ◽  
pp. 1-10
Author(s):  
J.M.F. Verhagen ◽  
R. Geers ◽  
M.W.A. Verstegen

In 4 almost identical trials, 159 Large White X Dutch Landrace gilts and castrated [male][male], weighing about 20 kg, were housed in groups of 10 and maintained at 15 degrees or 25 degrees C for 12 days; all pigs had previously been maintained at 20 degrees . For pigs maintained at 15 degrees and 25 degrees , daily intake of metabolizable energy averaged 1368+or-62.7 and 1462+or-109.4 kJ.kg-0.75 resp., and daily gain 596+or-28.9 and 622+or-76.8 g; differences between groups were significant. Groups did not differ significantly in heat production or feed conversion efficiency. For pigs housed at 15 degrees , feed intake increased from 1060+or-37.0 g per day at days 2-3 to 1375+or-26.5 g per day at days 11-12. Corresponding values for pigs housed at 25 degrees were 1125+or-29.0 and 1328+or-99.0 g per day. For both groups, heat production was significantly higher in the light than in the dark. Heat production in the light stopped increasing after 8 and 5 days resp. for pigs housed at 15 degrees and 25 degrees ; in the dark it stopped increasing after 6 days for pigs housed at 15 degrees . (Abstract retrieved from CAB Abstracts by CABI’s permission)


1972 ◽  
Vol 14 (1) ◽  
pp. 47-55 ◽  
Author(s):  
G. A. Lodge ◽  
M. E. Cundy ◽  
R. Cooke ◽  
D. Lewis

SUMMARYForty-eight gilts by Landrace sires on Large White × Landrace females were randomly allocated to eight pens and within pens to six treatment groups involving three diets and two levels of feeding from 23 to 59 kg live weight. All diets were formulated to have approximately the same ratio of digestible energy to crude protein (160 kcal DE/unit % CP) but different energy and protein concentrations: (A) 3500 kcal/kg DE and 21 % CP, (B) 3150 kcal/kg DE and 19% CP, and (C) 2800 kcal/kg DE and 17% CP. Amino acid balance was maintained relatively constant with synthetic lysine, methionine and tryptophan. The levels of feeding were such that the lower level of diet A allowed an intake of energy and protein similar to the higher level of diet B, and the lower level of B was similar to the higher level of C.On the lower level of feeding, growth rate, efficiency of feed conversion and carcass fat content increased linearly with each increment in nutrient concentration; on the higher level of feeding growth rate and EFC increased from diet C to B but not from B to A, whereas carcass fat content increased linearly with diet from the lowest to the highest concentration. There was a non-significant tendency for the higher density diets at a similar level of nutrient intake to give better EFC and fatter carcasses than the lower density diets.


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