scholarly journals The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing

2019 ◽  
Vol 294 (45) ◽  
pp. 16527-16534 ◽  
Author(s):  
Travis B. Lear ◽  
Karina C. Lockwood ◽  
Yurong Ouyang ◽  
John W. Evankovich ◽  
Mads B. Larsen ◽  
...  
Keyword(s):  
E3 Ligase ◽  
Nutrient Sensing ◽  
Ring Type

The RanBP2 SUMO E3 ligase is neither HECT- nor RING-type

2004 ◽  
Vol 11 (10) ◽  
pp. 984-991 ◽  
Author(s):  
Andrea Pichler ◽  
Puck Knipscheer ◽  
Hisato Saitoh ◽  
Titia K Sixma ◽  
Frauke Melchior
Keyword(s):  
E3 Ligase ◽  
Ring Type ◽  
Sumo E3 Ligase

scholarly journals A RING-type E3 ligase controls anther dehiscence by activating the jasmonate biosynthetic pathway geneDEFECTIVE IN ANTHER DEHISCENCE1in Arabidopsis

2013 ◽  
Vol 74 (2) ◽  
pp. 310-327 ◽  
Author(s):  
Yan-Jhu Peng ◽  
Ching-Fang Shih ◽  
Jun-Yi Yang ◽  
Choon-Meng Tan ◽  
Wei-Han Hsu ◽  
...  
Keyword(s):  
Biosynthetic Pathway ◽  
E3 Ligase ◽  
Anther Dehiscence ◽  
Ring Type

scholarly journals The ARRE RING-Type E3 Ubiquitin Ligase Negatively Regulates Cuticular Wax Biosynthesis in Arabidopsis thaliana by Controlling ECERIFERUM1 and ECERIFERUM3 Protein Levels

2021 ◽  
Vol 12 ◽  
Author(s):  
Shuang Liu ◽  
Meixuezi Tong ◽  
Lifang Zhao ◽  
Xin Li ◽  
Ljerka Kunst
Keyword(s):  
Ubiquitin Ligase ◽  
Uv Light ◽  
E3 Ubiquitin Ligase ◽  
E3 Ligase ◽  
Cuticular Wax ◽  
26S Proteasome ◽  
Covalent Attachment ◽  
Wax Deposition ◽  
E3 Ligases ◽  
Ring Type

The outer epidermal cell walls of plant shoots are covered with a cuticle, a continuous lipid structure that provides protection from desiccation, UV light, pathogens, and insects. The cuticle is mostly composed of cutin and cuticular wax. Cuticular wax synthesis is synchronized with surface area expansion during plant development and is associated with plant responses to biotic and abiotic stresses. Cuticular wax deposition is tightly regulated by well-established transcriptional and post-transcriptional regulatory mechanisms, as well as post-translationally via the ubiquitin-26S proteasome system (UPS). The UPS is highly conserved in eukaryotes and involves the covalent attachment of polyubiquitin chains to the target protein by an E3 ligase, followed by the degradation of the modified protein by the 26S proteasome. A large number of E3 ligases are encoded in the Arabidopsis genome, but only a few have been implicated in the regulation of cuticular wax deposition. In this study, we have conducted an E3 ligase reverse genetic screen and identified a novel RING-type E3 ubiquitin ligase, AtARRE, which negatively regulates wax biosynthesis in Arabidopsis. Arabidopsis plants overexpressing AtARRE exhibit glossy stems and siliques, reduced fertility and fusion between aerial organs. Wax load and wax compositional analyses of AtARRE overexpressors showed that the alkane-forming branch of the wax biosynthetic pathway is affected. Co-expression of AtARRE and candidate target proteins involved in alkane formation in both Nicotiana benthamiana and stable Arabidopsis transgenic lines demonstrated that AtARRE controls the levels of wax biosynthetic enzymes ECERIFERUM1 (CER1) and ECERIFERUM3 (CER3). CER1 has also been confirmed to be a ubiquitination substrate of the AtARRE E3 ligase by an in vivo ubiquitination assay using a reconstituted Escherichia coli system. The AtARRE gene is expressed throughout the plant, with the highest expression detected in fully expanded rosette leaves and oldest stem internodes. AtARRE gene expression can also be induced by exposure to pathogens. These findings reveal that wax biosynthesis in mature plant tissues and in response to pathogen infection is controlled post-translationally.

scholarly journals A phosphate-starvation induced RING-type E3 ligase maintains phosphate homeostasis partially through OsSPX2 in rice

2018 ◽  
Author(s):  
Jian Yang ◽  
Meng-yang Xie ◽  
Lan Wang ◽  
Zhi-li Yang ◽  
Zhi-hui Tian ◽  
...  
Keyword(s):  
E3 Ligase ◽  
Phosphate Starvation ◽  
Phosphate Homeostasis ◽  
Ring Type

scholarly journals Characterization of a Novel RING-Type Ubiquitin E3 Ligase GhRING2 Differentially Expressed in Cotton Fiber

2014 ◽  
Vol 05 (21) ◽  
pp. 3364-3379 ◽  
Author(s):  
Shiva Soma ◽  
Chuan-Yu Hsu ◽  
Sukumar Saha ◽  
Johnie N. Jenkins ◽  
Din-Pow Ma
Keyword(s):  
Cotton Fiber ◽  
E3 Ligase ◽  
Differentially Expressed ◽  
Ring Type ◽  
Ubiquitin E3 Ligase
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