scholarly journals 178EMBRYO QUALITY AND COLOR IN HOLSTEIN FRIESIAN AND BELGIAN BLUE CATTLE IN RELATION TO DONOR BLOOD CHOLESTEROL AND TRIGLYCERIDES

2004 ◽  
Vol 16 (2) ◽  
pp. 211 ◽  
Author(s):  
J.L.M.R. Leroy ◽  
L. Goossens ◽  
A. Geldhof ◽  
T. Vanholder ◽  
G. Opsomer ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Embryo Quality ◽  
Serum Triglyceride ◽  
Serum Total Cholesterol ◽  
Blood Cholesterol ◽  
Bovine Embryo ◽  
Serum Concentrations ◽  
Donor Blood ◽  
Serum Triglycerides ◽  
Holstein Friesian

Bovine embryo freezability is closely linked with quality and differs between cow breeds (Visintin JA et al., 2002 Theriogenology 57, 345–359). Dark embryos have a bad freezability, resulting in low pregnancy rates (Hill BR and Kuehner LF, 1998 Theriogenology 49, 168). Excessive accumulation of lipid droplets in dark embryos is suggested to be the cause of this inferior embryo quality and in turn may be influenced by the biochemical composition of the embryonic environment. In a field trial we studied the relationship between donor breed (Holstein Friesian dairy cows v. Belgian Blue beef cows), donor serum total cholesterol and triglyceride concentration, embryo quality and embryo color. The preliminary results are presented. Blood was drawn from Holstein Friesian (HF) (n=74) and Belgian Blue cows (BB) (n=55) prior to embryo flushing on Day 7 after superovulation and subsequent insemination. Serum was analyzed for total cholesterol and triglycerides using commercial photometric assays. Embryos were scored individually by the same operator for quality (excellent to bad: score 1 to 4) and for color: light (L), medium (M) or dark (D) using a binocular stereomicroscope (40X). Student’s t-test, chi-square test and Spearman correlations were used when appropriate. Holstein Friesian cows yielded significantly more embryos (±SEM) per flushing than did BB (6.0±0.59 v. 4.2±0.44) (P<0.05). However, significantly more HF embryos were classified as dark compared to the BB embryos (L, M, D: 39.4%, 43.8% and 16.8% v. 80.5%, 19.5% and 0% of the HF and BB embryos, respectively) (P<0.05). Significantly more BB embryos showed an excellent morphological quality (55.0% of BB embryos compared to 28.4% of HF embryos) (P<0.05). The serum concentrations (±SEM) of total cholesterol (148±5.9mgdL−1 v. 106±4.1mgdL−1) were significantly higher and the serum concentrations of triglycerides (19.6±0.71mgdL−1 v. 28.4±3.34mgdL−1) were significantly lower in HF compared to BB (P<0.05). Within the HF breed, there was a significant positive correlation between donor blood total cholesterol and the color of each embryo (r=0.545) and a negative correlation between serum triglycerides and embryo color (r=−0.484) (P<0.05). In our study, embryo quality and color as well as serum total cholesterol and triglyceride concentrations are clearly influenced by donor breed. Within the HF breed, darker embryos originate from donors with higher serum total cholesterol and lower serum triglyceride levels. These preliminary data suggest that factors influencing total cholesterol and triglyceride concentrations in the donor blood (e.g. breed, milk yield, nutrition) may influence embryo color and thus embryo lipid content, freezability and subsequent pregnancy rate.

scholarly journals Effect of Bortezomib on Total Cholesterol, Triglycerides and Histopathology Abdominal Aorta in Rats of Atherosclerosis Model

2020 ◽  
Vol 31 (2) ◽  
pp. 95
Author(s):  
Ismawati Ismawati ◽  
Ilhami Romus ◽  
Esy Maryanti ◽  
Nopi Permatasari ◽  
Elfiah Luthfianty
Keyword(s):  
Total Cholesterol ◽  
Abdominal Aorta ◽  
Cholesterol Oxidase ◽  
Proteasome Inhibitors ◽  
Serum Triglyceride ◽  
Serum Total Cholesterol ◽  
Serum Triglycerides ◽  
Atherosclerotic Lesions ◽  
Abdominal Aortic ◽  
And Control

<p>The effects of using proteasome inhibitors on atherosclerosis could be beneficial or detrimental. This study aimed to analyze the effects of proteasome inhibitors in the progression stage. Experimental animals (18 rats) were divided into three groups, namely control (C) as a group of rats given standard feed, P1 as atherosclerosis-induced rat group, and P2 as atherosclerosis-induced rat group and given proteasome inhibitors. Proteasome inhibitor administered was bortezomib at a dose of 50µg/kgBW/day intraperitoneally on day 1 and 3. After four days of treatment, the termination and measurement of serum total cholesterol, serum triglycerides, and abdominal aorta histopathology with hematoxylin-eosin staining were carried out. Serum total cholesterol levels were measured using the CHOD-PAP (Cholesterol Oxidase-Peroxidase Aminoantypirin) method, whereas serum triglyceride levels were measured using the GPO-PAP (glycerol phosphatase oxidase−phenol4-amino antipyrene peroxidase) method. Histopathological assessment was carried out with a scoring system in 9 fields of view with a 400x magnification, which was then averaged. The ANOVA test showed significant differences in serum total cholesterol, serum triglycerides, and abdominal aortic histopathology between atherosclerosis and control groups, but there were no significant differences in the administration of bortezomib in atherosclerosis except in serum triglyceride levels. It can be concluded that the administration of 50µg/kg bortezomib for four days in the rats model of the progression stage of atherosclerosis can decrease serum triglyceride levels, although it can not inhibit the formation of atherosclerotic lesions and has no effect on serum total cholesterol. </p>

scholarly journals 162 EMBRYO QUALITY AND COLOR IN HOLSTEIN FRIESIAN HEIFERS AND COWS IN RELATION TO SERUM PARAMETERS

2005 ◽  
Vol 17 (2) ◽  
pp. 232
Author(s):  
J.L.M.R. Leroy ◽  
L. Goossens ◽  
A. Geldhof ◽  
T. Vanholder ◽  
S. De Vliegher ◽  
...  
Keyword(s):  
Embryo Quality ◽  
Beef Cows ◽  
Bovine Embryo ◽  
Serum Concentrations ◽  
Chi Square ◽  
Serum Parameters ◽  
Holstein Friesian ◽  
Chi Square Test ◽  
Multiple Variables ◽  
Student’S T

Bovine embryo freezability is closely linked with quality and differs between breeds (Visintin JA et al. 2002 Theriogenology 57, 345–359). Dark embryos have a poor cryotolerance resulting in low pregnancy rates (Hill BR and Kuehner LF 1998 Theriogenology 49, 168), and are characterized by excessive accumulation of lipid droplets which in turn may be influenced by the biochemical composition of the embryonic environment. Earlier work revealed that Holstein Friesian (HF) cows yield significantly darker embryos compared to Belgian Blue beef cows (Leroy JLMR et al. 2004 Reprod. Fert. Dev. 16, 211). In this field examine we aimed to study the differences in embryo quality and color between HF cows (producing milk) and heifers (non-producing) in relation to four serum parameters that have previously been linked with embryo quality and fertility: urea, total protein (TP), total cholesterol (TC), and triglycerides (TG). Blood samples were collected from HF cows (n = 54) and HF heifers (n = 33) prior to embryo flushing on Day 7 after superovulation and subsequent insemination. Serum was stored frozen until assay with commercial photometric assays. Embryos were scored individually by the same operator for quality (excellent to poor: score 1 to 4) and color: light (L), medium (M), or dark (D) using a binocular stereomicroscope (40×). Independent Student's t-test and chi-square test were used when appropriate. Heifers and cows yielded on average (± SEM) 5.1 ± 0.82 and 6.1 ± 0.71 embryos per flushing, respectively. Significantly more cow embryos were classified as dark compared to heifer embryos (L, M, D: 20.4%, 55.5% and 24.1% vs. 70.8%, 27.4%, and 1.8%, for cow and heifer embryos, respectively) (P < 0.05). Significantly more heifer embryos showed an excellent morphological quality (62.5% of heifer embryos compared to 13.1% of cow embryos) (P < 0.05). Serum concentrations (± SEM) of urea (4.5 ± 0.2 vs. 2.8 ± 0.2 mM), TP (7.59 ± 0.07 vs. 6.57 ± 0.09 g/dL) and TC (183 ± 5.3 vs. 105 ± 3.8 mg/dL) were significantly higher and serum concentrations of TG (17.2 ± 0.6 vs. 23.8 ± 0.9 mg/dL) significantly lower in cows compared to heifers (P < 0.05). In this study, embryo color (i.e. lipid content) and quality as well as urea, TP, TC, and TG serum concentrations were clearly influenced by the production parameter (cow = producing vs. heifer = non-producing). These findings imply that producing milk (parity = 0 or >0) may be an important confounder. Therefore, this variable should be taken into account when studying multiple variables influencing embryo quality or color simultaneously. Further analyses are ongoing to reveal which factors at the cow level are affecting the embryo quality and color. This research was funded by IWT-Flanders (Grant no. 13236).

scholarly journals Studies on Serum Total Cholesterol, in Second and Third Trimester of Pregnancy

1970 ◽  
Vol 1 ◽  
pp. 1-4 ◽  
Author(s):  
F Husain ◽  
SA Latif ◽  
MM Uddin
Keyword(s):  
Pregnant Women ◽  
Total Cholesterol ◽  
Serum Total Cholesterol ◽  
Reproductive Age ◽  
Control Group ◽  
Serum Concentrations ◽  
Third Trimester ◽  
Medical College ◽  
Unpaired Student

Study was carried out in the department of physiology, Mymensingh Medical College, Mymensingh, Bangladesh during the period of July 2006 to June 2007 to investigate the effect of pregnancy on serum total cholesterol. The serum concentrations of total cholesterol was measured in 100 cases of 2nd and 3rd trimester of pregnancy and in a control group of 100 cases of non pregnant women which was matched on reproductive age. Data were analyzed by computer with SPSS program using unpaired student‘t’ test. The results showed that the pregnant women had significantly higher concentrations of serum total cholesterol. Higher concentration of total cholesterol was more common in pregnant than control and reaching maximum at 3rd trimester of pregnancy. This may be a purely physiological response to pregnancy or it may be indicative of pathology in some women. These results deserve a follow up study to investigative whether the hypercholesterolemia persists after parturition. Key Words: Total cholesterol, pregnancy, parturition, hypercholesterolemia J Bangladesh Soc Physiol. 2006 Dec;(1):1-4.

scholarly journals Serum Total Cholesterol and Triglyceride Status in Female Athletes

2011 ◽  
Vol 5 (2) ◽  
pp. 71-74
Author(s):  
Dilruba Akther ◽  
Ruhul Amin ◽  
US Naima Begum ◽  
Najneen Akhter ◽  
Nasrin Habib ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Female Athletes ◽  
Serum Triglyceride ◽  
Serum Total Cholesterol ◽  
Test Results ◽  
Cross Sectional ◽  
Medical College ◽  
Cholesterol Levels ◽  
Healthy Female ◽  
Regular Physical Exercise

Background: Exercise plays a role in preventing cardiovascular disease as well as other serious health problems. Objectives: A cross sectional comparative study was performed to observe the changes in serum total cholesterol and triglyceride in apparently healthy female athletes. Methods: This study was carried out in the Department of Physiology of Dhaka Medical College from July 2005 to June 2006. For this, 30 female athletes aged 17 to 38 years (experimental) who were under regular physical exercise training for at least two years and age matched 30 healthy female non athletes (control) for comparison were selected. Fasting serum Triglyceride and total Cholesterol levels of all the subjects were measured. Data were compared between athletes and non athletes and analyzed statistically by unpaired 't' test. Results: Mean±SD cholesterol levels were 141.10 ±14.46 & 165.10±7.03 and Mean±SD Triglyceride levels were 76.10±11.54 & 96.60±17.02 in athletes and non athletes respectively. Serum total cholesterol (p<0.001) and triglycerides (p<0.01) were significantly lower; in athletes compared to those of non athlets. Conclusion: From this study it can be concluded that, serum total cholesterol and triglycerides may be lowered in athletes. Key words: Female athletes; Cholesterol; Triglyceride. DOI: 10.3329/jbsp.v5i2.6780J Bangladesh Soc Physiol. 2010 December; 5(2): 71-74

scholarly journals Association of Serum Triglycerides and Total Cholesterol levels with Hypertension in Adult Female

2019 ◽  
Vol 7 (1) ◽  
pp. 35-39
Author(s):  
Nahid Yeasmin ◽  
Qazi Shamima Akhter ◽  
Sayeeda Mahmuda ◽  
Sharmin Nahar ◽  
Mahmuda Abira ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Total Cholesterol ◽  
Diastolic Blood Pressure ◽  
Adult Female ◽  
Serum Triglyceride ◽  
Control Group ◽  
Fasting Serum ◽  
Serum Triglycerides ◽  
Medical College ◽  
Female Subjects

Hyperlipidemia is one of the most widespread medical disorder in female and its complications are increasing all over the world, leading to life threatening medical problems like cardiovascular diseases, stroke and peripheral vascular diseases. An association between hyperlipidemia and hypertension has been identified. The study was carried out to observe the association of serum triglycerides and total cholesterol level with hypertension in adult female subjects. This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of January 2011 to December 2011. A total number of sixty female subjects were selected with age ranging from 30 to 50 years. Among them 30 female subjects with hypertension were included from the out-patient department of Medicine, Dhaka Medical College Hospital, Dhaka as study group (B) and 30 apparently healthy females were taken as control group (A) for comparison. Estimation of fasting serum triglycerides (TG) and total cholesterol (TC) levels were done by enzymatic method in the Department of Physiology, Dhaka Medical College Dhaka in both groups. Systolic blood pressure and diastolic blood pressure of all participants were recorded by standard method. Data were analyzed by Unpaired Student’s- test and Pearson's correlation co-efficient (r) test as applicable. The values of fasting serum TG level were significantly higher in subjects with hypertension than those of control. Fasting serum TC level was significantly higher in subjects with hypertension in comparison to controls also. In subjects with hypertension fasting serum TG and fasting serum TC levels were higher and showed positive correlation with systolic and diastolic blood pressure. Present study revealed that systolic and diastolic blood pressure has positive relationship with fasting serum triglyceride (TG) and fasting serum cholesterol (TC) levels. Bangladesh Crit Care J March 2019; 7(1): 35-39

scholarly journals A cross-sectional study of impact of dyslipidemia in stroke

2020 ◽  
Vol 7 (11) ◽  
pp. 1670
Author(s):  
Niranjan Ganesh Kanagarajan ◽  
Reema Ningthoukhongjam ◽  
Robinson Ningshen ◽  
Thangjam G. Singh ◽  
Vikie Khruomo
Keyword(s):  
Total Cholesterol ◽  
Serum Triglyceride ◽  
Cross Sectional Study ◽  
Abrupt Onset ◽  
Northeast India ◽  
Serum Total Cholesterol ◽  
Sectional Study ◽  
Lipid Levels ◽  
Cross Sectional ◽  
Average Serum

Background: Stroke is defined as abrupt onset of symptoms and/or sign of focal and global loss of cerebral function lasting for at least 24 hrs with no apparent cause other than of vascular origin. Dyslipidemia in stroke is not widely studied especially from the population of Northeast India (Manipur). Moreover, most prior studies did not specifically compare hemorrhagic stroke risk among those with elevated lipid levels to those with optimal or near optimal lipid levels. Therefore, we studied the levels of different Lipids in stroke patients (hemorrhagic and ischemic) to understand its role in pathogenesis of stroke.  Methods: This cross-sectional study was conducted in RIMS, Manipur from 2017-2019 and included 185 patients above 18 years with stroke within 48 hrs of onset of symptoms. NCCT brain and serum lipids, other related blood investigations were performed.Results: We found that serum total cholesterol, LDL-C and triglycerides are significantly higher in infarction patients with average levels of 210.82 mg/dl, 143.64 mg/dl and 151.50 mg/dl respectively which is statistically significant (p<0.001). The average serum total cholesterol, LDL-C and triglycerides are significantly lower in ICH patients with average levels of 143.34 mg/dl, 84.67 mg/dl and 113.94 mg/dl respectively which is statistically significant. (p<0.001).Conclusions: We concluded that raised level of serum total cholesterol, serum LDL-C, serum triglyceride are associated with cerebral infraction (p=0.001) and lower level of serum total cholesterol, serum LDL-C, serum triglyceride are associated with cerebral hemorrhage (p=0.001). Thus, serum lipid levels should be carefully monitored to prevent life threatening stroke.

scholarly journals A study of serum lipid profile in smokers and non-smokers: evaluation of role of smoking on lipid profile

2019 ◽  
Vol 7 (4) ◽  
pp. 1016
Author(s):  
Chandrashekar V. Kubihal ◽  
Hemalatha D. Naik
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Serum Lipid ◽  
Serum Triglyceride ◽  
Blood Cholesterol ◽  
Serum Lipid Profile ◽  
Serum Triglyceride Level ◽  
Cross Sectional ◽  
Cholesterol Levels ◽  
Increased Risk

Background: Several studies have reported elevated blood cholesterol levels among persons who regularly smoke cigarettes and lowered blood cholesterol levels among persons quitting smoking. Other studies have also shown that smoking lowers high density lipoprotein level, resulting in an increased risk of coronary heart disease. Smoking also leads to increase in LDL cholesterol and triglyceride levels. The objective was to study serum lipid profile in smokers and non-smokers.Methods: A cross sectional comparative study was carried in 100 subjects. The subjects were divided into two groups. First group consisted of 25 nonsmokers and second group of 75 smokers. The group of 75 smokers was again divided into three equal sub groups of 25 each depending upon the duration and intensity of smoking. Concentration of serum total cholesterol and HDL was determined by Zak’s method. Concentration of serum LDL and VLDL cholesterol was determined by Friedwald’s formula. Concentration of serum triglyceride level was determined by enzymatic end point peroxidase coupled method.Results: All the values of lipid profile i.e., total cholesterol, triglycerides, LDL, VLDL were found to be significantly higher among the smokers compared to the non-smokers. HDL value was significantly lower among smokers. As the degree of smoking increased from mild to heavy smokers, the values of total cholesterol, triglycerides, LDL and VLDL increased. The degree of smoking was inversely proportional to HDL values i.e., the HDL value decreased as the smoking degree increased.Conclusions: Thus, it can be said based on the present study that smoking affects and deranges the lipid profile of the person.

scholarly journals Effect of sex hormones on fasting serum triglycerides in baboons given high-sucrose diets

1971 ◽  
Vol 25 (3) ◽  
pp. 323-331 ◽  
Author(s):  
T. M Coltart ◽  
I Macdonald
Keyword(s):  
Sex Hormones ◽  
Serum Triglyceride ◽  
Sucrose Intake ◽  
Serum Concentrations ◽  
Fasting Serum ◽  
Serum Triglycerides ◽  
Male And Female ◽  
Sucrose Diet ◽  
Serum Triglyceride Concentration ◽  
High Sucrose

1. The incorporation of [14C]sucrose in to serum triglyceride was shown to increase in both male and female baboons after a period of high sucrose intake. During the same period of high sucrose intake there was an increase in the fasting serum triglyceride concentration of the male baboons but not of the females.2. When the male baboons were given a parenteral oestrogen preparation in addition to the sucrose diet the increase in fasting serum triglycerides was greatly reduced but there was little alteration in the extent of the incorporation of sucrose into serum triglyceride compared to that with the diet and no oestrogen.3. A parenteral testosterone preparation given to the female baboons in addition to sucrose diet had no effect on either the extent of incorporation of sucrose into triglyceride the fasting serum concentrations of triglyceride.4. The findings suggest that the differing patterns of fasting triglyceride response in the male and female baboons to the sucrose diet may have resulted from oestrogen enhancing the removal of triglyceride from the serum of the female animals.

scholarly journals Efficacy and safety of atorvastatin and rosuvastatin in ischemic heart disease patients: A prospective study

2021 ◽  
Vol 18 (7) ◽  
pp. 1533-1538
Author(s):  
Mariam Maqsood ◽  
Saleha Sadeeqa ◽  
Maqsood Ahmad ◽  
Hafsa Afzal
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Total Cholesterol ◽  
Randomized Trials ◽  
Creatine Phosphokinase ◽  
Density Lipoprotein ◽  
Ischemic Heart ◽  
Blood Cholesterol ◽  
Serum Triglycerides ◽  
A Prospective Study

Purpose: To compare the safety and efficacy of two commonly used statins namely; atorvastatin and rosuvastatin, and determine the efficiency of CoQ10 in the reversal of statin-induced myopathy. Methods: An investigational study design was adopted using randomized trials involving patients suffering from ischemic heart disease and receiving either atorvastatin or rosuvastatin. The study was conducted at Punjab Institute of Cardiology, Lahore, Pakistan during the period, November 2016 - February 2017. A total number of 95 male and female patients, between the ages of 40 and 80 years, were selected. Their blood samples were analyzed for lipid profile, total cholesterol, serum high-density lipoprotein-cholesterol (HDL-C), serum triglycerides, low-density lipoproteins-cholesterol (LDL-C) and total cholesterol/HDL-C ratio. Results: Gender and dose showed significant correlation with creatine phosphokinase (CPK) levels, (p = 0.001) and (p > 0.001), respectively. The patients using rosuvastatin 20 mg had a higher risk of developing myopathy than those treated with atorvastatin 40 mg (p = 0.023), while atorvastatin 20 mg patients were more prone to induce myopathy than 10 mg (p = 0.001) recipients. Atorvastatin 20 mg produced higher CPK levels than rosuvastatin 10 mg (p = 0.002). A substantial increase in CPK levels was found with rosuvastatin 20 mg and atorvastatin 20 mg usage (p > 0.001). It was observed that rosuvastatin 20 mg significantly increased the risk of myopathy compared to atorvastatin 10 mg (p > 0.001). However, rosuvastatin 20 mg/day considerably reduced the blood cholesterol as compared to atorvastatin 10mg/day (p = 0.001). CPK levels reduced significantly following treatment with CoQ10 (p = 0.022). Conclusion: Rosuvastatin users are more prone to the risk of myopathy, myalgic symptoms and rise in CPK levels than atorvastatin users, and these effects are dose related. CoQ10 is effective in lowering CPK levels and reversing myalgia.

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