Suppression of oestrus in Zebu heifers with melengestrol acetate

1989 ◽  
Vol 29 (6) ◽  
pp. 771
Author(s):  
PJS Hasker
Keyword(s):  
Pregnancy Rates ◽  
Post Treatment ◽  
Control Group ◽  
Treatment Control ◽  
The Third ◽  
Melengestrol Acetate ◽  
Significant Difference ◽  
Licking Behaviour ◽  
Treatment Control Group ◽  
Cessation Of Treatment

The value of melengestrol acetate (MGA) as a means of suppressing oestrus and its administration by utilising the licking behaviour of the animal were investigated in 3 groups of 30 Sahiwal cross heifers. For 63 days 0.5 mg MGA was either individually fed daily (fed group) or applied daily with molasses to the midrib of heifers to be licked off (licking group). The third group received no treatment (control group). When treatments ceased, fertile bulls were introduced for 11 weeks. The heifers were then slaughtered. Control animals exhibited oestrus regularly throughout the treatment period while those in the treated groups failed to exhibit oestrus after the first week. Post treatment oestrus was synchronised in the fed group but only partial synchronisation occurred in the licking group. Pregnancy rates from the first post-treatment oestrus of 63, 17 and 33% for the control, fed and licking groups respectively were significantly different (P<0.01). Pregnancy rates of 87, 60 and 80% from the first plus second post-treatment oestrus for the control, fed and licking groups respectively also differed significantly (P<0.05). There was no significant difference in the cumulative pregnancy rates after the third post-treatment oestrus. This study demonstrated that daily oral administration of MGA suppresses oestrus in heifers, but pregnancy rates following cessation of treatment are depressed. Application of MGA with molasses to an area on the coat to exploit the licking behaviour of the animal appeared successful. However, the practicability of the technique needs verification under extensive grazing conditions.

Anger, Arousal, and Systematic Desensitization

1973 ◽  
Vol 32 (2) ◽  
pp. 625-626 ◽  
Author(s):  
David R. Evans ◽  
Margaret T. Hearn ◽  
Donald Saklofske
Keyword(s):  
Nursing Students ◽  
Physiological Responses ◽  
Post Treatment ◽  
Control Group ◽  
Systematic Desensitization ◽  
Treatment Control ◽  
Anger Arousal ◽  
Treatment Control Group

The effect of systematic desensitization on semantic and physiological responses to anger-inducing scenes was examined with 20 nursing students. Pre- and post-treatment GSR, and semantic responses of a treatment and a no-treatment control group were obtained during exposure to anger-inducing scenes. Results supported the hypothesis that systematic desensitization reduces arousal and rated anger to the scenes.

scholarly journals Inefficacy of albendazole sulphoxide and ivermectin for the treatment of bovine parasitic otitis caused by rhabditiform nematodes

2009 ◽  
Vol 29 (11) ◽  
pp. 910-912 ◽  
Author(s):  
Guilherme G. Verocai ◽  
Julio I. Fernandes ◽  
Thaís R. Correia ◽  
Raquel M.P.S. Melo ◽  
Pedro Afonso M. Alves ◽  
...  
Keyword(s):  
Bos Taurus ◽  
Post Treatment ◽  
Control Group ◽  
Parasitic Disease ◽  
Treatment Control ◽  
Cattle Breeding ◽  
Administration Routes ◽  
Bos Taurus Indicus ◽  
Ear Canals ◽  
Treatment Control Group

The purpose of this study was to evaluate the efficacy of orally administered albendazole sulphoxide and pour-on ivermectin for the treatment of bovine parasitic otitis caused by rhabditiform nematodes. Eighteen Gyr cows presenting clinical otitis were divided in three groups with six animals each. The first one did not receive any treatment (control group). The second one was treated with 0.5% pour-on ivermectin, 500µg/kg of body weight, and the third group was treated with oral 6% albendazole sulphoxide, at 6.0mg/kg. Both ear canals of each animal were reexamined on days 7 and 21 post treatment. The animals in the control group remained infected throughout the days of observation. Ivermectin treatment did not show effectiveness on days 7 or 21 post treatment. The albendazole sulphoxide treatment had an efficacy of 16.7 and 25% on days 7 and 21, respectively. Further studies are required to assess an effective treatment for this parasitic disease, especially via alternative administration routes, because of its significant impact on Bos taurus indicus cattle breeding in Tropical and Subtropical Regions.

Treatment of Test Anxiety by Group Implosive Therapy

1973 ◽  
Vol 33 (2) ◽  
pp. 383-388 ◽  
Author(s):  
Harold H. Dawley ◽  
W. W. Wenrich
Keyword(s):  
Placebo Group ◽  
Test Anxiety ◽  
Therapy Group ◽  
Anxiety Reduction ◽  
The Other ◽  
Control Group ◽  
Treatment Control ◽  
Significant Difference ◽  
Implosive Therapy ◽  
Treatment Control Group

36 test anxious Ss were randomly assigned to 3 groups. One group served as the no-treatment control, while the other two groups received either placebo-attention or implosive therapy. Implosive therapy consisted of 5 30-min. sessions of treatment in which Ss were asked to imagine highly anxiety-evoking scenes pertaining to test anxiety while concentrating on experiencing the accompanying sensations as intensely as possible. The placebo group imagined non-relevant scenes while concentrating on experiencing the accompanying sensations as intensely as possible. The results indicated a significant difference in terms of anxiety reduction between the no-treatment control group and the implosive-therapy group. No significant difference was obtained between the placebo group and the implosive-therapy group, or between the placebo group and the no-treatment group. The importance of a placebo group in behavior therapy research was noted.

scholarly journals Impact of Somatosensory Training on Neural and Functional Recovery of Lower Extremity in Patients with Chronic Stroke: A Single Blind Controlled Randomized Trial

2021 ◽  
Vol 18 (2) ◽  
pp. 583
Author(s):  
Reem M. Alwhaibi ◽  
Noha F. Mahmoud ◽  
Mye A. Basheer ◽  
Hoda M. Zakaria ◽  
Mahmoud Y. Elzanaty ◽  
...  
Keyword(s):  
Physical Therapy ◽  
Lower Extremity ◽  
Functional Recovery ◽  
Intervention Group ◽  
Chronic Stroke ◽  
Post Treatment ◽  
Control Group ◽  
Stroke Patients ◽  
Significant Difference ◽  
Group Post

Recovery of lower extremity (LE) function in chronic stroke patients is considered a barrier to community reintegration. An adequate training program is required to improve neural and functional performance of the affected LE in chronic stroke patients. The current study aimed to evaluate the effect of somatosensory rehabilitation on neural and functional recovery of LE in stroke patients. Thirty male and female patients were recruited and randomized to equal groups: control group (GI) and intervention group (GII). All patients were matched for age, duration of stroke, and degree of motor impairment of the affected LE. Both groups received standard program of physical therapy in addition to somatosensory rehabilitation for GII. The duration of treatment for both groups was eight consecutive weeks. Outcome measures used were Functional Independent Measure (FIM) and Quantitative Electroencephalography (QEEG), obtained pre- and post-treatment. A significant improvement was found in the FIM scores of the intervention group (GII), as compared to the control group (GI) (p < 0.001). Additionally, QEEG scores improved within the intervention group post-treatment. QEEG scores did not improve within the control group post-treatment, except for “Cz-AR”, compared to pretreatment, with no significant difference between groups. Adding somatosensory training to standard physical therapy program results in better improvement of neuromuscular control of LE function in chronic stroke patients.

Protective effects of histamine on Gq-mediated relaxation in regenerated endothelium

2014 ◽  
Vol 306 (2) ◽  
pp. H286-H290 ◽  
Author(s):  
Calvin K. Chan ◽  
Song Yan Liao ◽  
Yue Lin Zhang ◽  
Aimin Xu ◽  
Hung Fat Tse ◽  
...  
Keyword(s):  
Area Under The Curve ◽  
Treated Group ◽  
Control Group ◽  
Protective Effects ◽  
Treatment Control ◽  
Porcine Coronary Artery ◽  
Endogenous Histamine ◽  
Coronary Endothelium ◽  
Treatment Control Group

In the porcine coronary artery, regenerated endothelium is dysfunctional as regards the responses to endothelium-dependent agonists. The current study aimed to determine the possible involvement of histamine in such dysfunction. Pigs were treated chronically with pyrilamine (H1 receptor inhibitor, 2 mg·kg−1·day−1) with part of their coronary endothelium and allowed to regenerate for 28 days after balloon denudation. The results showed a reduction in relaxation to bradykinin (Gq protein dependent) only in the pyrilamine-treated group (area under the curve, 269.7 ± 13.4 vs. 142.0 ± 31.0, native endothelium vs. regenerated endothelium) but not in the control group (253.0 ± 22.1 vs. 231.9 ± 29.5, native endothelium vs. regenerated endothelium). The differences in the relaxation to serotonin (Gi protein dependent) between native and regenerated endothelium were not affected by the pyrilamine treatment (control group, 106.3 ± 17.0 vs. 55.61 ± 12.7; and pyrilamine group, 106.0 ± 8.20 vs. 49.30 ± 6.31, native endothelium vs. regenerated endothelium). These findings indicate that during regeneration of the endothelium, the activation of H1 receptors by endogenous histamine may be required to maintain the endothelium-dependent Gq protein-mediated relaxation to bradykinin, suggesting a beneficial role of the monoamine in the process of endothelial regeneration.

A Treatment/Control Group Study of Growth Hormone Treatment

2000 ◽  
Vol 10 (Supplement 1) ◽  
pp. 31S-37S ◽  
Author(s):  
Barbara Y. Whitman ◽  
Susan Myers ◽  
Aaron Carrel ◽  
David Allen
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Control Group ◽  
Treatment Control ◽  
Treatment Control Group

scholarly journals Applicability of auriculotherapy in reducing stress and as a coping strategy in nursing professionals

2012 ◽  
Vol 20 (5) ◽  
pp. 980-987 ◽  
Author(s):  
Leonice Fumiko Sato Kurebayashi ◽  
Juliana Rizzo Gnatta ◽  
Talita Pavarini Borges ◽  
Maria Júlia Paes da Silva
Keyword(s):  
Positive Impact ◽  
Control Group ◽  
Control Groups ◽  
The Third ◽  
Stress Symptoms ◽  
Significant Difference ◽  
Stress Levels ◽  
Needle Control ◽  
Nursing Professionals ◽  
Reducing Stress

AIMS: randomized clinical trial aimed at evaluating the auriculotherapy in reducing stress levels in 75 nursing professionals and analyze the coping domains that have changed after treatment. METHODOLOGY: volunteers were divided into 3 groups (Control, Needles and Seeds) and received eight sessions at Shenmen, Kidney and Brainstem points. The Control Group didn't receive any intervention. RESULTS: ANOVA test showed statistical differences in stress levels for Needle/Control Groups in the third and fourth assessments, according to Stress Symptoms List when compared the three groups in four assessments. For the Inventory of Folkman/Lazarus, a significant difference was obtained for Spacing domain between needle/control. In analysis within the same group, differences were found for Confrontation in fourth assessment between Needle/Control Groups and for Social Support in the third one between Seeds/Control Groups. CONCLUSION: The auriculotherapy decreased stress levels, changed Coping domains after treatment, suggesting that both Auriculotherapy with needles and seeds can produce positive impact to improve strategy Coping in the nursing team. However, more studies are needed to conceive the extent of the technique.

Can placebos prevent intrusive memories?

2022 ◽  
Author(s):  
Tobias Kube ◽  
Irving Kirsch ◽  
Julia Glombiewski ◽  
Philipp Herzog
Keyword(s):  
Psychological Trauma ◽  
Traumatic Experiences ◽  
Control Group ◽  
Treatment Control ◽  
Open Label ◽  
Intrusive Memories ◽  
Experimental Psychopathology ◽  
Negative Appraisal ◽  
Treatment Control Group ◽  
Healthy Participants

After traumatic experiences, intrusive memories can flash back and evoke significant distress. Here, we investigated whether the occurrence of intrusions can be prevented by placebo. After the exposure to an experimental psychopathology model of psychological trauma, healthy participants (N=112) were randomised to deceptive placebo (DP), open-label placebo (OLP), or a no-treatment control group. The results show that one week later, the groups did not differ in the frequency of intrusive memories. However, participants receiving OLP reported the lowest intensity of intrusions. Participants receiving DP reported the lowest burden of intrusions. Across groups, the expectation that intrusions will be intense and hardly controllable was associated with a higher frequency of intrusions, higher distress, higher burden, and more negative appraisal. The results suggest that expectations play a crucial role in the emergence of intrusive memories and that at least some of the disabling aspects of intrusive memories can be reduced by placebo.

scholarly journals Identifying Key MicroRNAs Targeted by Narenmandula in a Rodent Nephropathy Model

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Xiulan Wang ◽  
Chun Chang ◽  
Wenjie Jin ◽  
Arun Arun ◽  
Sudunabuqi Sudunabuqi ◽  
...  
Keyword(s):  
Renal Function ◽  
Differential Expression ◽  
Target Genes ◽  
Enrichment Analysis ◽  
Control Group ◽  
Doxorubicin Hydrochloride ◽  
Treatment Control ◽  
Number Of Genes ◽  
Version 2.0 ◽  
Treatment Control Group

Background. Untreated nephropathy can progress to renal failure. The traditional Mongolian remedy Narenmandula regulates the kidney “yang.” This study aimed to identify key microRNAs (miRNAs) targeted by Narenmandula in a rat model of nephropathy. Methods. Fifteen rats exhibiting normal renal function were randomized to three study arms. Nephropathy was induced in n = 10 rats using doxorubicin hydrochloride, followed by either Narenmandula treatment (treatment group) or no treatment (control group). In n = 5 rats, no doxorubicin was given and renal function remained unchanged (healthy group). Microarray analysis identified miRNAs which were differentially expressed (DE-miRNAs) between groups. Target genes of DE-miRNAs were predicted using miRWalk version 2.0, followed by enrichment analysis using DAVID, and construction of the miRNA coregulatory network using Cytoscape. Results. Nephropathy was successfully induced, with doxorubicin resulting in differential expression of 3645 miRNAs (1324 upregulated and 2321 downregulated). Narenmandula treatment induced differential expression of a total of 159 miRNAs (102 upregulated and 57 downregulated). Upregulated DE-miRNAs (e.g., miR-497-5p, miR-195-5p, miR-181a-5p, miR-181c-5p, and miR-30e-5p) and downregulated DE-miRNAs (e.g., miR-330-3p and miR-214-3p) regulated a high number of target genes. Moreover, the miRNA pairs (e.g., miR-195-5p—miR-497-5p, miR-181a-5p—miR-181c-5p, and miR-30e-5p—miR-30a-5p) coregulated a high number of genes. Enrichment analysis indicated functional synergy between miR-30e-5p—miR-30a-3p, miR-34a-5p—miR-30e-5p, miR-30e-5p—miR-195-3p, and miR-30a-3p—miR-195-3p pairs. Conclusion. Narenmandula may modulate doxorubicin-induced nephropathy via targeting miR-497-5p, miR-195-5p, miR-181a-5p, miR-181c-5p, miR-30e-5p, miR-330-3p, miR-214-3p, miR-34a-5p, miR-30a-3p, and miR-30a-5p.

Resistance by cattle to cattle tick, Boophilus microplus. III. The development of resistance to experimental infestations by purebred Sahiwal and Australian Illawarra Shorthorn cattle

1971 ◽  
Vol 22 (2) ◽  
pp. 331 ◽  
Author(s):  
RW Hewetson
Keyword(s):  
Adult Female ◽  
Acquired Resistance ◽  
Boophilus Microplus ◽  
Cattle Tick ◽  
Control Group ◽  
The Third ◽  
Development Of Resistance ◽  
Significant Difference ◽  
Sahiwal Cattle ◽  
Males And Females

Purebred Sahiwal cattle acquired resistance to Boophilus microplus in a similar manner to crossbred Sahiwal cattle as previously reported. The purebred entire males and females were more resistant than a control group of crossbred steers because they dropped significantly fewer replete ticks than the crossbreds at the third and fourth, but not at the first and second infestations. Adult female ticks dropped by purebred animals were significantly lighter than those dropped by crossbred animals at the fourth infestation only. There was no significant difference in the numbers of eggs laid and hatched from ticks dropped by purebred and crossbred animals. Australian Illawarra Shorthorn steers developed resistance at a second and third infestation which waned at a fourth infestation, but individual steers displayed developing resistance throughout the four infestations. Day of modal drop of replete female ticks appeared to be affected by breed, and developing resistance or season.

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