scholarly journals Effects of Methoxinine, an Analogue of Methionine, on the Growth and Morphology of Wool Fibres

1986 ◽  
Vol 39 (3) ◽  
pp. 209 ◽  
Author(s):  
PJ Reis ◽  
DA Tunks ◽  
RDG Rigby ◽  
SG Munro ◽  
RW Edols

Methoxinine (O-methyl-DL-homoserine) was given to 18 Merino sheep by intravenous infusion or injection in amounts of 52-100 mg/kg body weight. Effects on strength, morphology and growth rate of wool fibres were studied.

1964 ◽  
Vol 6 (3) ◽  
pp. 309-319 ◽  
Author(s):  
S. K. Stephenson

1. Body shape and carcass composition have been measured in a dated series of Romney-Southdown cross and Australian Merino sheep foetuses.2. Large differences in shape exist between the two breed groups and these result from growth rate differences in certain components of the bone and muscle tissue.3. Carcass composition at any particular foetal weight, however, is more uniform. In relation to body weight, the Merino has a higher proportion of bone in the body but the proportion of muscle is the same in both breed groups. Nevertheless, the distribution of muscle tissue is changed as there s i a higher proportion of muscle in the hind limb of the Romney-Southdown cross.


1979 ◽  
Vol 32 (6) ◽  
pp. 561
Author(s):  
Z Leish ◽  
BA Panaretto

The effects of an 8-day intravenous infusion of dexamethasone (7�6 mg kg-o.75 body weight) on collagen biosynthes's and wool growth in skin were examined in four Merino wethers.


1980 ◽  
Vol 31 (4) ◽  
pp. 791
Author(s):  
DA Tunks ◽  
RDG Rigby ◽  
AM Downes ◽  
JA Lamberton ◽  
BA Panaretto ◽  
...  

Merino sheep, offered feed at two levels of intake, were given an oral dose of N-[5-(4-am1nophenoxy)- pentyllphthahmide at rates varying over 100-800 mg/kg body weight. Consistent defleecing was obtained at dose rates of 400 nig/kg and above. Feed intake did not Influence defleecing activity. lntravenous infusion of smaller amounts also allowed defleecing. Wool growth rate following dosing was not affected by a dose of 100 mg/kg, but doses of 200 and 400 mg/kg caused depressions of c. 15 and c. 70% respectively in the rate of wool growth in the 2 weeks after dosing. Blindness was observed In one sheep dosed at 400 mg/kg and In all sheep dosed at higher rates


1961 ◽  
Vol 1 (2) ◽  
pp. 85 ◽  
Author(s):  
AM Stewart ◽  
RJ Moir ◽  
PG Schinckel

The growth rate of wool was measured at monthly intervals for a period of two years in four groups totalling forty Merino sheep, maintained under typical farm conditions in a Mediterranean climatic environment. Marked seasonal fluctuation in wool growth was found in all sheep. The highest level of clean wool production, 85 attained in the spring months, was nearly three times that of the lowest level, which occurred in the autumn. The rate of wool growth fluctuated independently of body weight. Wool growth fell steep4 while bob weight was maintained; wool growth subsequently rose sharply while body weight increased relatively slowly. The factors responsible for the observed fluctuation in the rate of wool growth are discussed and the conclusion reached that lack of useful energy and protein, in the summer and autumn grazing is probably the principal cause of the decline in rate of wool growth in these months.


Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 392
Author(s):  
Lydia Katsika ◽  
Mario Huesca Flores ◽  
Yannis Kotzamanis ◽  
Alicia Estevez ◽  
Stavros Chatzifotis

This study was conducted to elucidate the interaction effects of temperature and dietary lipid levels (2 × 2 factorial experiment) on the growth performance, muscle, and liver composition in adult farmed European sea bass (Dicentrarchus labrax). Two groups of fish (190 g; 60 fish per group) were distributed in 12 tanks in triplicates and kept at two different temperature regimes; one starting at 23 °C and then changed to 17 °C for 61 days, and the other starting at 17 °C and then changed to 23 °C for 39 days. Two commercial diets containing both ~44% crude protein but incorporating different dietary lipid levels, 16.5% (D16) and 20.0% (D20) (dry matter (DM)), were fed to the fish to apparent satiation; the type of diet fed to each fish group remained constant throughout the experiment. Final body weight, weight gain, and specific growth rate were significantly higher for the fish group held at 23 °C compared to the fish group at 17 °C (before the temperature changes), while the dietary fat content did not have any profound effect in both groups. Furthermore, the different temperature regimes did not affect muscle or liver composition, but, on the contrary, dietary lipids affected hepatosomatic, perivisceral fat, and visceral indexes. Feed conversion ratio and specific growth rate were not affected by the dietary lipid level. An interaction of temperature and dietary lipid content was observed in daily feed consumption (DFC) and final body weight (FBW).


1989 ◽  
Vol 40 (2) ◽  
pp. 433 ◽  
Author(s):  
SI Mortimer ◽  
KD Atkins

Wool production traits were measured on Merino hogget ewes in an unselected multiple-bloodline flock over a 7-year period at Trangie Agricultural Research Centre, N.S.W. The traits measured were greasy fleece weight (GFW), skirted fleece weight (SKFW), yield (Y), clean fleece weight (CFW), fibre diameter (FD), body weight (BWT) and staple length (SL). These measurements were used to examine genetic differences between and within flocks of Merino sheep, and to estimate heritability of and genetic and phenotypic correlations among these traits. Significant strain, flock within strain and flock effects were present for all traits. Interactions between these effects and year were non-significant. Within-flock genetic variance was always larger than between-flock within strain genetic variance for each trait. The influence of environmental effects on these traits was also examined. The environmental effects of birth-rearing type, age at observation and age of dam together accounted for about 7-10% of the total within-flock variation in fleece weights and body weight.After adjusting for significant environmental effects, paternal half-sib heritability estimates were 0.29 �. 0.06 for GFW, 0.22 � 0.05 for SKFW, 0.35 � 0.05 for Y, 0.30 �0.06 for CFW, 0.48 �0.07 for FD, 0.34 �. 0.06 for BWT and 0.44 �0.07 for SL. Estimates for genetic and phenotypic correlations were in agreement with published estimates except for the genetic correlation between CFW and FD (0.40 �. 0.11), and the genetic correlations involving BWT, which were essentially zero. The implications of the results of this study for the genetic improvement of Merino sheep for wool production are discussed.


1994 ◽  
Vol 13 (1) ◽  
pp. 40-47 ◽  
Author(s):  
C.J. Perkin ◽  
R. Stejskal

Continuous intravenous infusion allows the intended clinical dosing regime to be better evaluated during preclinical studies. Depending on the test material and vehicle, infusion for up to 6 months in primates and 12 months in beagle dogs is possible, but 28 days is the most frequent duration. Under general anesthesia, medical grade catheters are placed in the vena cava via the femoral vein, passed subcutaneously, and exteriorized between the scapulae. A jacket and tether system are used to connect the catheter to an external pump for dosing and the animals are allowed to move freely within the cages. Dosing usually commences after a 1-week recovery period. Body weight gain, food intake, and general observations indicate that the procedure does not adversely affect the normal laboratory behavior of the animals. Test article infusion periods from a few minutes up to 24 h a day, 7 days a week are used; a low infusion rate ofsaline is used for the balance of the 24-h period. Dosage volumes up to 120 ml/kg/day can be infused for 28 days and larger volumes for shorter periods. Up to three separate catheters can be inserted to allow coadministration of compounds for assessment of potential interactions. Body weight, ophthalmoscopy, blood sampling, electrocardiography, and indirect blood pressure measurement can be performed during infusion. Histopathologic common changes in all species include thrombosis, proliferation of vascular intima, and various local inflammatory changes at the infusion site in the vicinity of the catheter tip. These generally are considered to be due to physical irritation by the catheter. Secondary changes include pulmonary microemboli or thrombosis and histiocytosis in hepatic sinusoids often with erythrophago-cytosis. The main findings associated with infusion of very large volumes are reticulocytosis and increased hematopoiesis. These spontaneous findings must be distinguished from those possibly related to administration of the test material and/or vehicle.


2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Jianru Pan ◽  
Huocong He ◽  
Ying Su ◽  
Guangjin Zheng ◽  
Junxin Wu ◽  
...  

GST-TAT-SOD was the fusion of superoxide dismutase (SOD), cell-permeable peptide TAT, and glutathione-S-transferase (GST). It was proved to be a potential selective radioprotector in vitro in our previous work. This study evaluated the in vivo radioprotective activity of GST-TAT-SOD against whole-body irradiation. We demonstrated that intraperitoneal injection of 0.5 ml GST-TAT-SOD (2 kU/ml) 2 h before the 6 Gy whole-body irradiation in mice almost completely prevented the splenic damage. It could significantly enhance the splenic antioxidant activity which kept the number of splenic white pulp and consequently resisted the shrinkage of the spleen. Moreover, the thymus index, hepatic antioxidant activity, and white blood cell (WBC) count of peripheral blood in irradiated mice pretreated with GST-TAT-SOD also remarkably increased. Although the treated and untreated irradiated mice showed no significant difference in the growth rate of animal body weight at 7 days postirradiation, the highest growth rate of body weight was observed in the GST-TAT-SOD-pretreated group. Furthermore, GST-TAT-SOD pretreatment increased resistance against 8 Gy whole-body irradiation and enhanced 30 d survival. The overall effect of GST-TAT-SOD seemed to be a bit more powerful than that of amifostine. In conclusion, GST-TAT-SOD would be a safe and potentially promising radioprotector.


2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Shi-Peng Zhu ◽  
Yu-wei He ◽  
Huan Chen ◽  
Zhi-Fang Sun ◽  
Na Ding ◽  
...  

Objective. To observe the effect of preventive acupuncture and moxibustion on blood lipid of menopause rats.Methods. Seventy 10-month-old SD rats with estrous cycle disorders were divided into three control groups and four treatment groups (n=10/group) and another ten 3.5-month-old female SD rats were chosen as young control group. Preventive acupuncture and moxibustion were applied at Guanyuan (CV 4). Body weight growth rate has been recorded. Plasma total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), and high density lipoprotein (HDL) levels and uterusE2level were measured.Results. Compared to young control group, plasma TC and LDL increased and uterusE2reduced significantly in 12-month-old control group. Compared to 12-month-old control group, plasma TC and LDL level and body weight growth rate decreased while HDL level increased remarkably in preventive acupuncture 12-month-old group. Compared to 14-month-old control group, plasma TC level and body weight growth rate decreased remarkably in preventive moxibustion 14-month-old group.Conclusions. Preventive acupuncture and moxibustion can significantly decrease the plasma TG and LDL, increase the plasma HDL, and prevent fat accumulation. Our finding suggests that preventive acupuncture and moxibustion have beneficial effects on blood lipid. Different treatment effects were found between preventive acupuncture and preventive moxibustion.


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