Relationships between Oesophagostomum columbianum infection and the nutritional status of sheep. II. Haematological changes

1969 ◽  
Vol 20 (3) ◽  
pp. 601 ◽  
Author(s):  
RJ Bawden
Keyword(s):  
Single Dose ◽  
Nutritional Status ◽  
Cell Volume ◽  
Packed Cell Volume ◽  
Haemoglobin Concentration ◽  
High Protein ◽  
Low Protein ◽  
Oesophagostomum Columbianum ◽  
Haematological Changes ◽  
The Mean

Young sheep maintained on a low protein ration showed significant reductions in haemoglobin concentration, packed cell volume, and number of circulating erythrocytes following infection with 1500 Oesophagostomum columbianum larvae. Similar infections of sheep maintained on a high protein ration had no significant effect on the various haematological values. The development of anaemia in the inadequately fed sheep was more severe in those animals which had been infected with five consecutive daily doses of 300 larvae than in those which had received 1500 larvae in a single dose. Little change was apparent throughout the experiment in the values for the mean corpuscular values of volume, haemoglobin, and haemoglobin concentration.

Relationships between Oesophagostomum columbianum infection and the nutritional status of sheep. III. Serum and tissue protein changes

1969 ◽  
Vol 20 (5) ◽  
pp. 965 ◽  
Author(s):  
RJ Bawden
Keyword(s):  
Single Dose ◽  
Nutritional Status ◽  
Serum Protein ◽  
High Protein ◽  
Pathological Features ◽  
Tissue Protein ◽  
Protein Depletion ◽  
Low Protein ◽  
Oesophagostomum Columbianum ◽  
Protein Group

The infection of young sheep with 1500 infective Oesophagostomum columbianum larvae was associated with the development of hypoproteinaemia resulting basically from a hypoalbuminaemia. Hypogammaglobulinaemia and hyperbetaglobulinaemia also developed in the infected animals. The concentration of α-globulin in the serum was not affected by infection. The extent and duration of the pathological features in the serum protein concentrations varied with the plane of nutrition. More severe effects were noted in sheep which had been maintained on a low protein ration and which exhibited severe protein depletion of the liver, spleen, and thymus, than in animals on a high protein ration. Within the low protein group the most severe depressions in serum protein concentrations resulted from infection with small multiple doses of larvae compared with the same total number given in a single dose.

Pathological changes associated with Oesophagostomum columbianum infestations in sheep: Haematological observations on control worm-free and experimentally infested sheep.

1967 ◽  
Vol 18 (3) ◽  
pp. 523 ◽  
Author(s):  
C Dobson
Keyword(s):  
Cell Volume ◽  
Packed Cell Volume ◽  
Haemoglobin Concentration ◽  
White Cell ◽  
General Increase ◽  
Corpuscular Haemoglobin ◽  
Cell Counts ◽  
Oesophagostomum Columbianum ◽  
Mean Corpuscular Haemoglobin ◽  
Corpuscular Haemoglobin Concentration

Variations in the numbers of erythrocytes and white cells within the blood of sheep given various doses of Oesophagostomum columbianum larvae were studied over a period of 10 weeks. The sheep showed losses of red cells and haemoglobin, and the packed cell volume was diminished after infestation with O. columbianum. These effects increased in severity as the infesting dose was increased; the resistant state of the host also affected the blood picture. In all infestations the calculated absolute values for the blood, i.e. mean corpuscular haemoglobin (MCH), mean corpuscular volume (MCV), and mean corpuscular haemoglobin concentration (MCHC), did not significantly change except in the heavier infestations, where MCV increased for a time. The type of anaemia which predominated throughout these experiments was normocytic-normochromic. Where the MCV increased for a period, the anaemia was of the macrocytic-normochromic type. During the first infestation with 2000 larvae the anaemias tended to become microcytiohyperchromic, but these changes were not significant. Gross observations on the gut indicated that one of the factors influencing the development of anaemias was the extensive tissue damage caused by the larvae, which resulted in chronic bleeding from the mucosa. This suggestion was supported by the fact that anaemias also developed during second infestations when there was no adult worm population. The white cell counts from a number of these sheep were also recorded. The most significant changes occurred after second infestation, although a general increase was noted after all first infestations as well; prominent increases occurred in the agranulocytes and the eosinophil leucocytes. The neutrophil leucocyte counts fell throughout all the infestation. All the normal values obtained for the haemoglobin concentration, packed cell volume, red cell counts, MCV, MCH, and MCHC and white cell counts compared favourably with the values cited by other workers.

scholarly journals Effect of Halothane and Enflurane Anaesthesia on the Level of Reduced Glutathione in Human Red Blood Cells

1980 ◽  
Vol 8 (3) ◽  
pp. 356-358 ◽  
Author(s):  
N. S. Agar ◽  
G. B. H. Lewis
Keyword(s):  
Cell Volume ◽  
Packed Cell Volume ◽  
Blood Cells ◽  
Reduced Glutathione ◽  
Haemoglobin Concentration ◽  
Red Cell ◽  
Anaesthetic Agents ◽  
Human Red Blood Cells ◽  
Enflurane Anaesthesia ◽  
Before And After

No significant changes were found in packed cell volume, haemoglobin concentration and red cell glutathione levels in patients before and after anaesthesia with halothane or enflurane. These results, though unable to explain the mechanism, support the earlier suggestion that glutathione plays little, if any, role in protecting liver against toxic effects of these anaesthetic agents or their metabolites.

The Causation of Splenomegaly in Schistosomiasis in Mice

1978 ◽  
Vol 54 (4) ◽  
pp. 397-401
Author(s):  
Adel A. F. Mahmoud ◽  
A. W. Woodruff
Keyword(s):  
Immune Response ◽  
Schistosoma Mansoni ◽  
Life Span ◽  
Cell Volume ◽  
Packed Cell Volume ◽  
Significant Extent ◽  
Haematological Changes

1. Mice were infected with fertile bisexual Schistosoma mansoni and compared with similar animals infected with unisexual worms or sterile bisexual worms. 2. A significant increase in splenic weight occurred in all infected animals. 3. Administration of well-tolerated doses of 6-mercaptopurine abolished the increase in relative splenic weight in animals infected with ordinary S. mansoni. 4. In splenectomized uninfected mice leucocytosis but no other haematological changes developed. 5. In splenectomized mice lower values for packed cell volume were observed 8 weeks after, but not 12 weeks after, infection with S. mansoni. 6. Slight prolongation of the life-span of erythrocytes occurred in splenectomized infected mice. 7. It is concluded that anaemia in schistosomiasis depends to a significant extent on immunity developed to adult schistosomal worms and can develop in the absence of schistosomal ova. 8. The anaemia resulting from such an immune response may be suppressed by administration of 6-mercaptopurine. 9. Such anaemia occurs even in splenectomized mice; thus hypersplenism is not necessary for its development although splenectomy slightly prolongs the erythrocyte life-span.

scholarly journals BLOOD PROFILES OF GREEN SEA TURTLE BEFORE AND AFTER THE REHABILITATION

2020 ◽  
Vol 9 (6) ◽  
pp. 930-939
Author(s):  
Ida Bagus Windia Adnyana ◽  
Ida Bagus Nararya Primastana Adnyana ◽  
Siswanto Siswanto
Keyword(s):  
Cell Volume ◽  
Packed Cell Volume ◽  
Haemoglobin Concentration ◽  
Chelonia Mydas ◽  
Sea Turtle ◽  
Corpuscular Haemoglobin ◽  
Turtle Conservation ◽  
Before And After ◽  
Mean Corpuscular Haemoglobin ◽  
Corpuscular Haemoglobin Concentration

Penyu adalah satwa yang terancam punah, sehingga upaya konservasinya perlu ditingkatkan. Kegiatan yang berhubungan dengan konservasi dimaksud adalah rehabilitasi penyu pascamengalami periode out of the water sebelum dilepasliarkan kembali ke alam bebas. Penelitian ini bertujuan untuk mengetahui perbedaan profil dan indeks eritrosit penyu hijau (Chelonia mydas) sebelum dan sesudah mengalami rehabilitasi di Turtle Conservation and Education Center (TCEC) di Pulau Serangan, Denpasar. Penelitian ini menggunakan sampel Sembilan ekor penyu hijau hasil sitaan Polisi Sektor Kuta, Badung, Bali. Sebanyak 2,5 mL darah perifer penyu hijau diambil dari sinus cervicalis dorsalis disimpan di tabung berisikan antikoagulan litium heparin dan dilanjutkan dengan pemeriksaan hematologi. Penentuan nilai total eritrosit dihitung dengan hemositometer. Kadar hemoglobin (Hb) diukur menggunakan Hemoglobinometer Sahli, sedangkan kadar Packed Cell Volume (PCV) ditentukan dengan metode mikrohematokrit. Indeks eritrosit yang meliputi Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH) dan Mean Corpuscular Haemoglobin Concentration (MCHC) dihitung dengan rumus konvensional yang ditentukan untuk itu. Data hasil penelitian dianalisis secara deskriptif kuantitatif menggunakan uji T berpasangan. Nilai profil darah (Packed Cell Volume, total eritrosit, Hemoglobin) mengalami peningkatan signifikan pasca rehabilitasi dengan nilai rerata hematokrit sebelum rehabilitasi sebesar 28,4±3,09 menjadi 31,7±2,87, nilai total eritrosit sebelum rehabilitasi sebesar 0,44±0,10 menjadi 0,56±0,15, nilai Hemoglobin sebelum rehabilitasi sebesar 6,3±1,28 menjadi 7,53±0,73 serta hasil perhitungan secara statistika dengan uji T-berpasangan menunjukkan profil darah penyu hijau sebelum dan sesudah rehabilitasi memiliki perbedaan yang signifikan yang berarti proses rehabilitas yang dilakukan di Turtle Conservation and Education Center, Serangan berhasil.

scholarly journals Prevalence of Anaemia at Booking amongst Antenatal Clinic Attendees in Some Health Facilities in Ogoni, South-South Nigeria

2021 ◽  
pp. 176-182
Author(s):  
S. Eli ◽  
G. P. Tee Popnen ◽  
D. G. B. Kalio ◽  
N. C. T. Briggs ◽  
K. E. Okagua
Keyword(s):  
Developing Countries ◽  
Cell Volume ◽  
Packed Cell Volume ◽  
Antenatal Clinic ◽  
Health Care Facilities ◽  
The World ◽  
The Mean ◽  
Anaemia In Pregnancy ◽  
In Pregnancy

Background: Anaemia in pregnancy is an indirect cause of maternal mortality. Myriad of factors predispose pregnant women to anaemia in pregnancy in the developing countries of the world of which poverty, illiteracy and ignorance are central. The prevalence of anaemia in the developing countries of the world is between 32% and 62.2%. Objective: To determine the prevalence of anaemia amongst antenatal clinic attendees in Ogoni, South-South Nigeria and offer preventive measures. Material and Methods: This was a retrospective four months cross-sectional study of antenatal clinic attendees at booking in three (3) primary health care facilities and general hospitals Bori and Tera, in Ogoni, South-South Nigeria. Three hundred and eighty (380) pregnant women’s biodata including their packed cell volume were collected. These pieces of information were computed using a structured proforma. The data were coded and analysed using statistical package for social sciences (SPSS) software version 25. Results: The mean age of the study antenatal clinic attendees was 28 years. The mean gestational age at booking was 25weeks. The range for the packed cell volume was 25% to 36% and the mean packed cell volume at booking was 30%. Three hundred and eighteen (318) (84.0%) had anaemia (with packed cell volume less than 33%). Majority of patients 249 (65.6%) had mild anaemia There was none with severe anaemia. Majority of patients had secondary level of education represented by 275 (72.3%). Conclusion: The prevalence of anaemia amongst antenatal clinic attendees at Ogoni was 84.0%. The role of pre-pregnancy care amongst women desirous of pregnancy, familly planning and the role of education cannot be over emphasized in the prevention of anaemia in pregnancy.

scholarly journals Immune response kinetics in Nigerian indigenous chickens challenged with attenuated Salmonella

2020 ◽  
Vol 47 (2) ◽  
pp. 57-67
Author(s):  
M. A. Opoola ◽  
A. S. Adenaike ◽  
O. A. Jegede ◽  
N. I Akutubuola ◽  
A. J. Fajemisin ◽  
...  
Keyword(s):  
Immune Response ◽  
Red Blood Cells ◽  
Cell Volume ◽  
Antibody Titre ◽  
Packed Cell Volume ◽  
Blood Cells ◽  
Haemoglobin Concentration ◽  
High Titre ◽  
Naked Neck ◽  
Indigenous Chickens

Salmonella infection is a major cause of death in chickens and this disease can be transferred through meat and egg to humans. The use of antibiotics and vaccines in the prevention and control of this infection are not totally efficient and also have their side effects. Therefore, genetic control is a better approach in finding a lasting solution. One hundred and ten chickens (4th generation) comprising the three genotypes of Nigerian indigenous chickens(NIC) that had shown divergent response (high vs low) to sheep red blood cells antigens were used in this study to investigate the immune response kinetics in NIC after challenged with attenuated Salmonella. There were six classes namely, high titre normal, low titre normal, high titre frizzle, low titre frizzle, high titre naked neck and low titre naked neck. Haematological parameters: packed cell volume (PCV), haemoglobin concentration (Hb),red blood cells count (RBC), white blood cells count (WBC), heterophils (H), lymphocytes (L), eosinophils (E), basophils (B), monocytes (M) and heterophils-lymphocytes ratio (HLR) were used to assess the immune responses of the chickens and data collected were subjected to General Linear Model procedure of SAS 9.2 version. The results showed that genotypeantibody titre had significant effect (p<0.05) on the immune response parameters but sex had no significant effect (p>0.05), while sex by genotype-antibody titre interaction had significant effect (p<0.05). The immune response kinetics of the chickens after challenge with attenuated Salmonella was shown by the significance of the effect of days of blood collection after challenge. High titre naked neck chickens recorded the highest PCV, Hb and RBC values while genotype-antibody titre had no significant effect (p>0.05) on the rest of the parameters. Low titre naked neck males recorded the highest PCV, HB and RBC values while the rest of the parameters were not significant (p>0.05). Generally, days had significant effect (p<0.05) on all the immune response parameters except on H, L and HLR. The study showed that the high titre naked neck males were least affected by the Salmonella vaccine in terms of decrease in packed cell volume, haemoglobin concentration and red blood cell count while the low titre normal females were most affected.

Corrigendum to: IGF-I is not a useful marker for nutritional status in the growing pig under commercial conditions

2001 ◽  
Vol 52 (7) ◽  
pp. 791
Author(s):  
L. Ma ◽  
F. R. Dunshea ◽  
Y. M. Brockwell ◽  
R. L. Inglis ◽  
D. J. Kingston ◽  
...  
Keyword(s):  
Weight Gain ◽  
Nutritional Status ◽  
Dietary Protein ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Low Protein ◽  
Igf I ◽  
Protein Diets

Plasma hormone concentrations were measured in gilts after fasting, long-term protein restriction, or supplementation. In 11-week-old pigs fasted overnight, plasma insulin, glucagon, gastrin, urea, and glucose were increased 30 min after re-feeding (P < 0.05), whereas IGF-I did not change. In 16-week-old gilts fed a standard commercial diet [14.6% crude protein (CP)], or a high-protein diet (16.7% CP) for 4 weeks, the high-protein diet increased weight gain (13%; P < 0.05) and carcass weight (4%; P < 0.05), but did not alter plasma IGF-I, insulin, or glucagon. In 10-week-old gilts fed high-protein diets (19.4% and 18.3% CP), or low-protein diets (15.5% and 13.3% CP) for 12 weeks during the grower and finisher phases, respectively, the low-protein diet decreased weight gain (18%; P < 0.001) and carcass weight (11%; P < 0.01), with a marked increase in plasma glucagon (P < 0.05), no change in insulin, and only a trend towards decreased IGF-I (P = 0.1). The pigs were more sensitive to altered dietary protein at 10 weeks of age than at 16 weeks. Plasma IGF-I was not responsive to the short-term effects of feeding or the long-term effects of dietary protein. Glucagon could provide a useful marker for nutritional status in young pigs, provided that time of feeding is taken into account.

scholarly journals Changes of haematological parameters in common pheasant throughout the year

2012 ◽  
Vol 51 (No. 1) ◽  
pp. 29-34 ◽  
Author(s):  
K. Hauptmanova ◽  
M. Maly ◽  
I. Literak
Keyword(s):  
Cell Volume ◽  
Packed Cell Volume ◽  
Haemoglobin Concentration ◽  
Reproductive Activity ◽  
Haematological Parameters ◽  
Phasianus Colchicus ◽  
Common Pheasant ◽  
Mean Corpuscular Haemoglobin ◽  
The Common ◽  
Corpuscular Haemoglobin Concentration

The haematological parameters of the common pheasant (Phasianus colchicus), the dynamics of changes in blood count parameters with regard to the season of the year and reproduction status, and the effects of sex and body condition on the haematological parameters of blood were studied. In total, 574 blood samples were collected. The samples were collected from pheasants from the age of 6 months, prior to the laying period, and after the laying period. Packed cell volume and haemoglobin concentration significantly increased in males during the period of growth and decreased during the period of reproductive activity. Significantly higher values were detected in males compared to females in erythrocyte count, packed cell volume, haemoglobin concentration and in mean corpuscular haemoglobin concentration. A statistically significant positive relationship was detected between weight and the values of most of the parameters related to red blood cells.

Sign in / Sign up

Export Citation Format

Share Document