Studies on salt tolerance of sheep. VIII. The tolerance of grazing ewes and their lambs for drinking waters of the types obtained from underground sources in Australia

1968 ◽  
Vol 19 (4) ◽  
pp. 589 ◽  
Author(s):  
AW Peirce
Keyword(s):  
Body Weight ◽  
Salt Concentration ◽  
Salt Content ◽  
Control Group ◽  
Water Control ◽  
Reservoir Water ◽  
Drinking Waters ◽  
Weight Gains ◽  
Chloride Water ◽  
Synthetic Water

Groups of 50–60 ewes grazing sown pastures near Adelaide, S.A., were offered various solutions as drinking waters. In two experiments these comprised: (1) reservoir water (control group); (2) synthetic water containing salts in the proportions found in many underground waters in South and Western Australia ("chloride water") with a total salt concentration of 1.30%; (3) synthetic water resembling the waters obtained in Queensland from the Great Artesian Basin ('bicarbonate water') with a total salt concentration of 0.50%. In a third experiment one group received reservoir water and another group received a chloride water containing I .00% total salts. The ewes were mated, they lambed, and they reared their lambs in the paddocks while receiving the various waters. In at least one experiment, pregnant ewes, lactating ewes, and weaned lambs received the saline waters during the months of high environmental temperatures, with associated high water intakes. The chloride water with a total salt concentration of 1.30% led to a reduction in the percentage of ewes that lambed in one experiment, but not in the other. It also led to decreased body weight gains of the lambs in both experiments, and in addition to diarrhoea and increased mortality in one experiment. Chloride water with 1.00% total salts led to decreased body weight gains and reduced wool production, without apparently adversely affecting the health of the lambs. Bicarbonate water with a total salt content of 0.50% had no adverse effect on the lambs in either experiment, but in one of these experiments it did lead to a reduction in the percentage of ewes that lambed. The implications of the findings in relation to the use of saline drinking waters under field conditions are discussed.

Studies on salt tolerance of sheep. VII. The tolerance of ewes and their lambs in pens for drinking waters of the types obtained from underground sources in Australia

1968 ◽  
Vol 19 (4) ◽  
pp. 577 ◽  
Author(s):  
AW Peirce
Keyword(s):  
Salt Concentration ◽  
Total Concentration ◽  
Total Duration ◽  
The Body ◽  
Control Group ◽  
Reservoir Water ◽  
Drinking Waters ◽  
Saline Waters ◽  
Chloride Water ◽  
Synthetic Water

Groups of eight or 10 ewes were fed in pens on a ration of chaffed lucerne and wheaten hays and oats and were offered various solutions as drinking waters. In two experiments these comprised: (1) reservoir water (control group); (2) synthetic water containing salts in the proportions found in many underground waters in South and Western Australia ("chloride water") with a total salt concentration of 1.30%; or (3) synthetic water resembling the waters obtained in Queensland from the Great Artesian Basin ("bicarbonate water") with a total salt concentration of 0.50%. In a third experiment the total concentration of salts in the chloride water was only 1.00%, that of the bicarbonate water again being 0.50%. The ewes were mated, they lambed, and they reared their lambs on the experimental regime until the lambs were weaned at the age of approximately 10 weeks. The weaned lambs were continued on the treatment for a further 5 months, the total duration of each experiment being 13 months. The commencement dates of the experiments were separated by intervals of approximately 6 months; by this arrangement pregnant ewes, lactating ewes, and weaned lambs received, in at least one experiment, the saline waters during the months of high environmental temperatures, with the associated high water intakes. There was some indication in one experiment of a poorer reproductive performance by the ewes receiving either chloride (1.30% total salts) or bicarbonate water as compared with the control group. The intake of saline waters in all experiments was higher than that of reservoir water, the increases ranging from 20 to 50%. The body weight increases during early pregnancy of the ewes receiving saline waters were identical with those of the corresponding control groups. Significantly lower body weights, as compared with the control group, were observed at one period only in one group of treated lambs receiving chloride water with a concentration of 1.30% total salts. Reductions in the sodium, potassium, and chloride concentrations in the plasma occurred in some groups receiving saline water. No effect was observed on concentrations of calcium, while the effect on magnesium was variable. No adverse effects were observed on health, food consumption, or wool production of the ewes and lambs as a result of drinking any of the saline waters. It is suggested that under the conditions of the experiment, ewes and their lambs could tolerate drinking water of either the chloride type with 1.00% total salts or the bicarbonate type with 0.50*#37; total salts.

scholarly journals Post-castration variations in weight gain in a cohort of young adult male cats

2014 ◽  
Vol 3 ◽  
Author(s):  
Alfreda Wei ◽  
Andrea J. Fascetti ◽  
Kyoungmi Kim ◽  
Jon J. Ramsey
Keyword(s):  
Body Weight ◽  
Retrospective Study ◽  
Weight Gain ◽  
Control Group ◽  
Controlled Environment ◽  
Housing Conditions ◽  
Wide Range ◽  
Weight Gains ◽  
Control Food ◽  
Ad Libitum

AbstractThe predisposition of cats to gain weight following neutering is well established; however, there is little information about the distribution and range of post-neutering weight gains observed in cats under a controlled environment. This retrospective study investigated 6-month post-castration weight gain and distribution of percentage body weight (BW) change in a cohort of twenty, male domestic shorthair cats relative to a control group of intact cats. Cats were matched in age (2·0–2·6 years), husbandry conditions and consumed ad libitum the same dry maintenance diet for at least 3 months prior to and 6 months following castration. All cats were castrated within 48 h of each other. All cats gained weight after castration. Mean BW was 4·67 (sd 0·70) kg at the start of the study and 5·93 (sd 1·38) kg at the end of the study, with individual weight gain ranging 3–53 % at 6 months post-neutering. The pre-conception BW of the queens of each cat was compared with the pre- and post-neutering BW of their offspring. The pre-conception BW of the queens was significantly correlated with the offspring's initial BW (ρ = 0·65, P = 0·01), final BW (ρ = 0·67, P = 0·01) and percentage BW change (ρ = 0·54, P = 0·04). A wide range of post-castration weight gains was observed among cats of similar backgrounds and housing conditions. Implementation of effective methods to control food consumption pre-conception and post-neutering may be a strategy for preventing obesity and obesity-related disorders in cats.

The effect of phytogenic feed additives on the performance, meat quality and coccidial infection rates of rabbits

2017 ◽  
Author(s):  
Stanislaw Lapiñski ◽  
Leszek Gacek ◽  
Joanna Gawroñska ◽  
Iwona Guja ◽  
Jerzy Kowal ◽  
...  
Keyword(s):  
Body Weight ◽  
Meat Quality ◽  
Food Additives ◽  
Feed Additives ◽  
Garlic Extract ◽  
Control Group ◽  
Weight Gains ◽  
Coccidial Infection ◽  
Positive Effect ◽  
Herbal Supplementation

The aim of the study was to evaluate the effect of herbal supplementation on rabbits’ health and production parameters. In experiment with herbal food additives, at 90 days of age animals fed with phytogenic additives (oregano, garlic and rosemary) had higher body weight compared to the group fed with coccidiostat. In experiment with herbal water additives (garlic extract or oregano) the phytobiotic supplementation had no effect on weight gains of animals. The highest body weight on slaughter day was obtained by rabbits drank water with garlic extract. Parasitological tests performed at 91 days of age showed that lowest average number of coccidia oocysts per gram of faeces (OPG) in  “garlic” group (48.0 OPG) and the highest in control group (308.6 OPG). The research showed that feed with herbal supplementation is willingly eaten by rabbits, contributes to faster weight gains and has a positive effect on meat quality.

scholarly journals PARTITIONING AVERAGE AND HETEROTIC COMPONENTS OF DIRECT AND MATERNAL GENETIC EFFECTS ON GROWTH IN MICE USING CROSSFOSTERING TECHNIQUES

Genetics ◽  
1976 ◽  
Vol 84 (1) ◽  
pp. 113-124
Author(s):  
J Nagai ◽  
H Bakker ◽  
E J Eisen
Keyword(s):  
Body Weight ◽  
Selection Response ◽  
Genetic Effects ◽  
Control Group ◽  
Correlated Responses ◽  
Secondary Importance ◽  
Body Weights ◽  
Weight Gains ◽  
The Individual ◽  
Linear Contrasts

ABSTRACT Crossfostering was performed using lines selected for increased 6-week body weight (H6) and increased 3-to 6-week postweaning gain (M16) and their reciprocal F1 crosses as nurse dams in the selected crossfostering group, and base population controls (C2, ICR) and their reciprocal F1 crosses in the control group. The offspring suckled were H6, M16 and F2 crosses in the selected group, and C2, ICR and their F2 crosses in the control group. Measurements taken on the individual offspring were body weights at birth (WB) and at 12, 21, 31, 42, and 63 days (W12, W21, W31, W42 and W63, respectively) and weight gains between adjacent ages (GB-12, G12–21, G21–31, G31–42 and G42–63, respectively). Least squares constants fitted to populations of genetic and nurse dams were used to calculate specific linear contrasts. Correlated responses to selection in average direct genetic effects were significant and positive for all traits examined in both H6 and M16, while the correlated responses in average maternal genetic effects were negative in M16 and negligible in H6. Selection response was primarily due to average direct genetic effects while the contribution of average maternal genetic effects was of secondary importance. The response in average direct genetic effects was smaller in M16 than in H6 through weaning (WB, W12 and W21), but was larger in M16 for postweaning weights (W31, W42 and W63). The correlated responses in average maternal genetic effects were consistently smaller in M16 than in H6. Direct heterosis was significant for all traits except for G12–21 and G42–63 in the control group, whereas maternal heterosis was significant for weight gains at early ages and for body weights. Direct heterosis tended to be larger than maternal heterosis in both selected and control crosses. Percent direct heterosis for body weight was larger in the selected crosses relative to the control crosses through 31 days of age, but the trend was reversed by 63 days. Percent maternal heterosis was consistently larger in the selected crosses.

scholarly journals Changes in the Urinary Metabolites in Losartan-Treated Spontaneously Hypertensive Rats

2021 ◽  
Vol 6 (1) ◽  
pp. 32-45
Author(s):  
Norasikin Ab Azis ◽  
Mohd Saleh Ahmad Kamal ◽  
Zurain Radjeni ◽  
Ahmed Mediani ◽  
Renu Agarwal
Keyword(s):  
Body Weight ◽  
Spontaneously Hypertensive Rats ◽  
Urinary Metabolites ◽  
Metabolite Profile ◽  
Proton Nuclear Magnetic Resonance ◽  
Control Group ◽  
Hypertensive Rats ◽  
Water Control ◽  
Spontaneously Hypertensive ◽  
Group 2

Introduction: This study examined the association of losartan induced changes in urinary metabolomic profile with the changes in blood pressure (BP) and renin-angiotensin- aldosterone system (RAAS) in spontaneously hypertensive rats (SHR). Methods: Male SHR were administered with either 0.5 mL of distilled water (control group, n=6) or 10 mg.kg -1 of losartan (group 2, n=6) daily by oral gavage for 4 weeks. Body weight, BP, food and water intake were measured weekly. At week 4, urine was collected for urinary electrolyte analysis and metabolite profiling, after which the animals were euthanised by decapitation and blood was collected for analysis of components of RAAS and electrolyte concentrations. Urine metabolite profile of SHR was determined using proton nuclear magnetic resonance ( 1 H-NMR) spectrometry combined with multivariate data analysis. Results: At week 4, losartan- treated SHR had significantly lower BP than non-treated SHR. There were no differences in water and food intake, body weight, serum and urinary electrolyte concentrations or in their urinary excretions between the two groups. No differences were evident in the components of RAAS except that the angiotensinogen level was significantly higher in losartan-treated SHR compared to non-treated SHR. Orthogonal partial least squares discriminant analysis (OPLS-DA) showed clear separation of urinary metabolites between control and losartan-treated SHR. Losartan-treated SHR group was separated from the control group by changes in the intermediates involved in glycine, serine and threonine metabolism. Conclusion: Antihypertensive effect of losartan in SHR seems to be associated with changes in urinary metabolite profile, particularly involving the metabolism of glycine, serine and threonine.

Studies on salt tolerance of sheep. VI. The tolerance of wethers in pens for drinking waters of the types obtained from underground sources in Australia

1966 ◽  
Vol 17 (2) ◽  
pp. 209 ◽  
Author(s):  
AW Peirce
Keyword(s):  
Sodium Chloride ◽  
Sea Water ◽  
Rain Water ◽  
Control Group ◽  
Health Food ◽  
Water Control ◽  
Underground Waters ◽  
Drinking Waters ◽  
Group 2 ◽  
Saline Solutions

Seven groups, each of six wether sheep, were fed in pens for 15 months on a ration of chaffed lucerne and wheaten hays and were offered various solutions as drinking waters. These comprised: (1) rain-water (control group); (2) 1.30% sodium chloride; (3) and (4) synthetic waters containing salts in the proportions found in many underground waters in South and Western Australia (referred to in this paper as "chloride waters"), with total concentrations of 0.65 and 1.30% respectively; (5) and (6) synthetic waters resembling those obtained in Queensland from the Great Artesian Basin ("bicarbonate waters"), with total salt concentrations of 0.20 and 0.50% respectively; and (7) sea-water diluted with rain-water to a total salt concentration of 1.30%The intake of all saline solutions, except that of the bicarbonate water with a concentration of 0.20% salts, was higher than that of rain-water, the increases ranging from 80% for 1.30% sodium chloride to 15% for the more concentrated bicarbonate water. The intake also increased in all groups with temperature, being 40-90 % higher in the hottest months than in the coldest months.Compared with the control group a significant decrease in wool production was observed only in the group receiving bicarbonate water with 0.50% total salts. These sheep also produced significantly less wool, for at least a portion of the experiment, than did those receiving the other synthetic mixtures of salts.The concentrations of potassium, calcium, and chloride in the blood plasma were not affected by the saline drinking waters. The concentrations of sodium at times were higher in the plasma of the control group and lower in the plasma of group 2 (1.30% sodium chloride) than in that of the remaining groups. Magnesium concentrations at times were higher in group 7 (diluted sea-water) and lower in group 2 than in the remaining groups. None of the solutions used in the experiment had any adverse effect on general health, food consumption, or weight increase.

L-Ascorbic Acid Addition to Chitosan Reduces Body Weight in Overweight Women

2014 ◽  
Vol 84 (1-2) ◽  
pp. 5-11 ◽  
Author(s):  
Eun Y. Jung ◽  
Sung C. Jun ◽  
Un J. Chang ◽  
Hyung J. Suh
Keyword(s):  
Ascorbic Acid ◽  
Body Weight ◽  
Fat Body ◽  
Body Weight Gain ◽  
Skinfold Thickness ◽  
The Body ◽  
Control Group ◽  
Percentage Body Fat ◽  
Overweight Women ◽  
Body Weights

Previously, we have found that the addition of L-ascorbic acid to chitosan enhanced the reduction in body weight gain in guinea pigs fed a high-fat diet. We hypothesized that the addition of L-ascorbic acid to chitosan would accelerate the reduction of body weight in humans, similar to the animal model. Overweight subjects administered chitosan with or without L-ascorbic acid for 8 weeks, were assigned to three groups: Control group (N = 26, placebo, vehicle only), Chito group (N = 27, 3 g/day chitosan), and Chito-vita group (N = 27, 3 g/day chitosan plus 2 g/day L-ascorbic acid). The body weights and body mass index (BMI) of the Chito and Chito-vita groups decreased significantly (p < 0.05) compared to the Control group. The BMI of the Chito-vita group decreased significantly compared to the Chito group (Chito: -1.0 kg/m2 vs. Chito-vita: -1.6 kg/m2, p < 0.05). The results showed that the chitosan enhanced reduction of body weight and BMI was accentuated by the addition of L-ascorbic acid. The fat mass, percentage body fat, body circumference, and skinfold thickness in the Chito and Chito-vita groups decreased more than the Control group; however, these parameters were not significantly different between the three groups. Chitosan combined with L-ascorbic acid may be useful for controlling body weight.

Tryptophan-Niacin Metabolism in Rat with Puromycin Aminonucleoside-Induced Nephrosis

2006 ◽  
Vol 76 (1) ◽  
pp. 28-33 ◽  
Author(s):  
Yukari Egashira ◽  
Shin Nagaki ◽  
Hiroo Sanada
Keyword(s):  
Body Weight ◽  
Urinary Excretion ◽  
Enzyme Activities ◽  
Treated Group ◽  
Control Group ◽  
Puromycin Aminonucleoside ◽  
Low Level ◽  
Key Enzyme

We investigated the change of tryptophan-niacin metabolism in rats with puromycin aminonucleoside PAN-induced nephrosis, the mechanisms responsible for their change of urinary excretion of nicotinamide and its metabolites, and the role of the kidney in tryptophan-niacin conversion. PAN-treated rats were intraperitoneally injected once with a 1.0% (w/v) solution of PAN at a dose of 100 mg/kg body weight. The collection of 24-hour urine was conducted 8 days after PAN injection. Daily urinary excretion of nicotinamide and its metabolites, liver and blood NAD, and key enzyme activities of tryptophan-niacin metabolism were determined. In PAN-treated rats, the sum of urinary excretion of nicotinamide and its metabolites was significantly lower compared with controls. The kidneyα-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) activity in the PAN-treated group was significantly decreased by 50%, compared with the control group. Although kidney ACMSD activity was reduced, the conversion of tryptophan to niacin tended to be lower in the PAN-treated rats. A decrease in urinary excretion of niacin and the conversion of tryptophan to niacin in nephrotic rats may contribute to a low level of blood tryptophan. The role of kidney ACMSD activity may be minimal concerning tryptophan-niacin conversion under this experimental condition.

Systemic Thrombin Generation and Activity Resistant to Low Molecular Weight Heparin Administered Prior to Streptokinase in Patients with Acute Myocardial Infarction

1997 ◽  
Vol 77 (01) ◽  
pp. 057-061 ◽  
Author(s):  
Dennis W T Nilsen ◽  
Lasse Gøransson ◽  
Alf-Inge Larsen ◽  
Øyvind Hetland ◽  
Peter Kierulf
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Molecular Weight ◽  
Body Weight ◽  
Low Molecular Weight Heparin ◽  
Troponin T ◽  
Bleeding Complications ◽  
Control Group ◽  
Low Molecular Weight ◽  
Creatine Kinase Mb

SummaryOne hundred patients were included in a randomized open trial to assess the systemic factor Xa (FXa) and thrombin inhibitory effect as well as the safety profile of low molecular weight heparin (LMWH) given subcutaneously in conjunction with streptokinase (SK) in patients with acute myocardial infarction (MI). The treatment was initiated prior to SK, followed by repeated injections every 12 h for 7 days, using a dose of 150 anti-Xa units per kg body weight. The control group received unfractionated heparin (UFH) 12,500 IU subcutaneously every 12 h for 7 days, initiated 4 h after start of SK infusion. All patients received acetylsalicylic acid (ASA) initiated prior to SK.Serial blood samples were collected prior to and during the first 24 h after initiation of SK infusion for determination of prothrombin fragment 1+2 (Fl+2), thrombin-antithrombin III (TAT) complexes, fibrinopeptide A (FPA) and cardiac enzymes. Bleeding complications and adverse events were carefully accounted for.Infarct characteristics, as judged by creatine kinase MB isoenzyme (CK-MB) and cardiac troponin T (cTnT), were similar in both groups of patients.A comparable transient increase in Fl+2, TAT and FPA was noted irrespective of heparin regimen. Increased anti-Xa activity in patients given LMWH prior to thrombolytic treatment had no impact on indices of systemic thrombin activation.The incidence of major bleedings was significantly higher in patients receiving LMWH as compared to patients receiving UFH. However, the occurrence of bleedings was modified after reduction of the initial LMWH dose to 100 anti-Xa units per kg body weight.In conclusion, systemic FXa- and thrombin activity following SK-infusion in patients with acute MI was uninfluenced by conjunctive LMWH treatment.

Overtraining of aerobic physical exercise reduce rats (Rattus norvegicus) memory

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Ni Made Ridla Parwata
Keyword(s):  
Body Weight ◽  
Physical Exercise ◽  
Rattus Norvegicus ◽  
Research Method ◽  
Male Rat ◽  
Control Group ◽  
Adult Male Rat ◽  
The Subject ◽  
Heavy Training

Overtraining syndrome is a decrease in physical capacity, emotions and immunity due to training that is too often without adequate periods of rest. Overtraining is often experienced by athletes who daily undergo heavy training with short break periods. This research aims to look at the effect of overtraining aerobic physical exercise on memory in mice. The research method was experimental in vivo with the subject of adult male rat (Rattus Norvegicus) Winstar strain aged 8-10 weeks, body weight 200-250 gr. Divided into three groups, namely the control group, aerobic group and overtraining group. The results of memory tests with water E Maze showed an increase in the duration of travel time and the number of animal errors made by the overtraining group (p = 0.003). This study concludes that overtraining aerobic physical exercise can reduce memory in rat hippocampus.

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