scholarly journals Temporin A as a prophylactic agent against methicillin sodium-susceptible and methicillin sodium-resistant Staphylococcus epidermidis vascular graft infection

2002 ◽  
Vol 36 (5) ◽  
pp. 1027-1030 ◽  
Author(s):  
Roberto Ghiselli ◽  
Andrea Giacometti ◽  
Oscar Cirioni ◽  
Federico Mocchegiani ◽  
Fiorenza Orlando ◽  
...  
Keyword(s):  
Staphylococcus Epidermidis ◽  
Vascular Graft ◽  
Graft Infection ◽  
Vascular Graft Infection ◽  
Prophylactic Agent ◽  
Temporin A

scholarly journals Temporin A Soaking in Combination with Intraperitoneal Linezolid Prevents Vascular Graft Infection in a Subcutaneous Rat Pouch Model of Infection with Staphylococcus epidermidis with Intermediate Resistance to Glycopeptides

2004 ◽  
Vol 48 (8) ◽  
pp. 3162-3164 ◽  
Author(s):  
Andrea Giacometti ◽  
Oscar Cirioni ◽  
Roberto Ghiselli ◽  
Fiorenza Orlando ◽  
Giuseppina D'Amato ◽  
...  
Keyword(s):  
Staphylococcus Epidermidis ◽  
Vascular Graft ◽  
Graft Infection ◽  
Prosthetic Graft ◽  
Vascular Graft Infection ◽  
Methicillin Resistant ◽  
Prosthetic Graft Infection ◽  
Intermediate Resistance ◽  
Temporin A

ABSTRACT The efficacy of linezolid and temporin A in the prevention of prosthetic graft infection due to methicillin-resistant Staphylococcus epidermidis with intermediate resistance to glycopeptides was investigated in a subcutaneous rat pouch model. Linezolid and temporin A, alone or combined, greatly reduced the bacterial numbers compared to the effect with control drugs.

Experimental Treatment of Vascular Graft Infection due to Staphylococcus epidermidis by In Situ Replacement with a Rifampin-bonded Polyester Graft

2001 ◽  
Vol 15 (4) ◽  
pp. 421-429 ◽  
Author(s):  
Marc Coggia ◽  
Olivier Goëau-Brissonnière ◽  
Véronique Leflon ◽  
Marie-Hélène Nicolas ◽  
Jean-Claude Pechère
Keyword(s):  
Staphylococcus Epidermidis ◽  
Vascular Graft ◽  
Graft Infection ◽  
Experimental Treatment ◽  
Vascular Graft Infection ◽  
In Situ Replacement

In-vivo evaluation of the effect of cyanoacrylate on prosthetic vascular graft infection – does cyanoacrylate increase the severity of infection?

VASA ◽  
2020 ◽  
Vol 49 (4) ◽  
pp. 281-284
Author(s):  
Atıf Yolgosteren ◽  
Gencehan Kumtepe ◽  
Melda Payaslioglu ◽  
Cuneyt Ozakin
Keyword(s):  
Vascular Graft ◽  
Graft Infection ◽  
Vascular Graft Infection ◽  
Group 4 ◽  
Significant Difference ◽  
Group 3 ◽  
Group 2 ◽  
Prosthetic Vascular Graft Infection ◽  
Group 1

Summary. Background: Prosthetic vascular graft infection (PVGI) is a complication with high mortality. Cyanoacrylate (CA) is an adhesive which has been used in a number of surgical procedures. In this in-vivo study, we aimed to evaluate the relationship between PVGI and CA. Materials and methods: Thirty-two rats were equally divided into four groups. Pouch was formed on back of rats until deep fascia. In group 1, vascular graft with polyethyleneterephthalate (PET) was placed into pouch. In group 2, MRSA strain with a density of 1 ml 0.5 MacFarland was injected into pouch. In group 3, 1 cm 2 vascular graft with PET piece was placed into pouch and MRSA strain with a density of 1 ml 0.5 MacFarland was injected. In group 4, 1 cm 2 vascular graft with PET piece impregnated with N-butyl cyanoacrylate-based adhesive was placed and MRSA strain with a density of 1 ml 0.5 MacFarland was injected. All rats were scarified in 96th hour, culture samples were taken where intervention was performed and were evaluated microbiologically. Bacteria reproducing in each group were numerically evaluated based on colony-forming unit (CFU/ml) and compared by taking their average. Results: MRSA reproduction of 0 CFU/ml in group 1, of 1410 CFU/ml in group 2, of 180 200 CFU/ml in group 3 and of 625 300 CFU/ml in group 4 was present. A statistically significant difference was present between group 1 and group 4 (p < 0.01), between group 2 and group 4 (p < 0.01), between group 3 and group 4 (p < 0.05). In terms of reproduction, no statistically significant difference was found in group 1, group 2, group 3 in themselves. Conclusions: We observed that the rate of infection increased in the cyanoacyrylate group where cyanoacrylate was used. We think that surgeon should be more careful in using CA in vascular surgery.

scholarly journals Surgical Management of Vascular Graft Infection in Severely Ill Patients by Partial Resection of the Infected Prosthesis

2007 ◽  
Vol 33 (5) ◽  
pp. 610-613 ◽  
Author(s):  
M. Mirzaie ◽  
J.D. Schmitto ◽  
T. Tirilomis ◽  
S. Fatehpur ◽  
O.J. Liakopoulos ◽  
...  
Keyword(s):  
Surgical Management ◽  
Vascular Graft ◽  
Graft Infection ◽  
Partial Resection ◽  
Vascular Graft Infection
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