Experimental Treatment of Vascular Graft Infection due to Staphylococcus epidermidis by In Situ Replacement with a Rifampin-bonded Polyester Graft

2001 ◽  
Vol 15 (4) ◽  
pp. 421-429 ◽  
Author(s):  
Marc Coggia ◽  
Olivier Goëau-Brissonnière ◽  
Véronique Leflon ◽  
Marie-Hélène Nicolas ◽  
Jean-Claude Pechère
Keyword(s):  
Staphylococcus Epidermidis ◽  
Vascular Graft ◽  
Graft Infection ◽  
Experimental Treatment ◽  
Vascular Graft Infection ◽  
In Situ Replacement

scholarly journals Treatment of vascular graft infection by in situ replacement with cryopreserved aortic allografts: An experimental study

1998 ◽  
Vol 27 (4) ◽  
pp. 689-698 ◽  
Author(s):  
Christoph Knosalla ◽  
Olivier Goëau-Brissonnière ◽  
Véronique Leflon ◽  
Patrick Bruneval ◽  
Michel Eugène ◽  
...  
Keyword(s):  
Experimental Study ◽  
Vascular Graft ◽  
Graft Infection ◽  
Vascular Graft Infection ◽  
In Situ Replacement

scholarly journals Treatment of vascular graft infection by in situ replacement with a rifampin-bonded gelatin-sealed Dacron graft

1994 ◽  
Vol 19 (4) ◽  
pp. 739-744 ◽  
Author(s):  
Olivier Goëau-Brissonnière ◽  
Frédéric Mercier ◽  
Marie Hélène Nicolas ◽  
François Bacourt ◽  
Marc Coggia ◽  
...  
Keyword(s):  
Vascular Graft ◽  
Graft Infection ◽  
Dacron Graft ◽  
Vascular Graft Infection ◽  
In Situ Replacement

scholarly journals Temporin A Soaking in Combination with Intraperitoneal Linezolid Prevents Vascular Graft Infection in a Subcutaneous Rat Pouch Model of Infection with Staphylococcus epidermidis with Intermediate Resistance to Glycopeptides

2004 ◽  
Vol 48 (8) ◽  
pp. 3162-3164 ◽  
Author(s):  
Andrea Giacometti ◽  
Oscar Cirioni ◽  
Roberto Ghiselli ◽  
Fiorenza Orlando ◽  
Giuseppina D'Amato ◽  
...  
Keyword(s):  
Staphylococcus Epidermidis ◽  
Vascular Graft ◽  
Graft Infection ◽  
Prosthetic Graft ◽  
Vascular Graft Infection ◽  
Methicillin Resistant ◽  
Prosthetic Graft Infection ◽  
Intermediate Resistance ◽  
Temporin A

ABSTRACT The efficacy of linezolid and temporin A in the prevention of prosthetic graft infection due to methicillin-resistant Staphylococcus epidermidis with intermediate resistance to glycopeptides was investigated in a subcutaneous rat pouch model. Linezolid and temporin A, alone or combined, greatly reduced the bacterial numbers compared to the effect with control drugs.

scholarly journals Silver-coated dacron prosthesis in the treatment of infection in arterial surgery: Case reports

2008 ◽  
Vol 136 (7-8) ◽  
pp. 410-413 ◽  
Author(s):  
Dragoslav Nenezic ◽  
Predrag Matic ◽  
Predrag Gajin ◽  
Nenad Ilijevski ◽  
Petar Popov ◽  
...  
Keyword(s):  
Conservative Treatment ◽  
Vascular Graft ◽  
Graft Infection ◽  
Artery Aneurysm ◽  
Ptfe Graft ◽  
Vascular Graft Infection ◽  
Left Groin ◽  
Anastomotic Pseudoaneurysm ◽  
Number Of Patients

INTRODUCTION Although the incidence is low, infection of prosthetic vascular graft bears a high incidence of serious complications including 25-75% mortality rate and 40-75% limb loss. The standard treatment of vascular graft infection consists of excision of the prosthesis, wound debridement and extraanatomic revascularization. Conservative treatment might be an option in a limited number of patients. We present three cases of surgical and conservative treatment of vascular graft infection. CASE OUTLINE Case 1: A patient developed silver-coated graft infection after femorodistal arterial reconstruction performed because of critical limb ischemia. In the early postoperative period, massive skin and subcutaneous tissue necrosis developed, with the graft being exposed. After two months of persistent debridement and wound toilette, the defect was covered with a Thiersch skin graft. Case 2: PTFE graft infection in the right groin followed reconstruction of the isolated common femoral artery aneurysm. This graft was replaced with a silver-coated graft in situ. Reinfection of the proximal end of the implanted silver-coated graft occurred and the graft was exposed. After repeated debridement and wound toilette, the exposed prosthesis was covered with granulomatous tissue, and the wound healed. Case 3: A year after anastomotic pseudoaneurysm resection in the left groin, prosthesis was exposed following wound infection. This graft was substituted with a silver-coated graft in situ. The wound healed primarily. CONCLUSION These three cases demonstrate that under some circumstances vascular prosthesis infection can be successfully treated conservatively without graft removal, and also by in situ replacement using silver-coated graft.

scholarly journals Temporin A as a prophylactic agent against methicillin sodium-susceptible and methicillin sodium-resistant Staphylococcus epidermidis vascular graft infection

2002 ◽  
Vol 36 (5) ◽  
pp. 1027-1030 ◽  
Author(s):  
Roberto Ghiselli ◽  
Andrea Giacometti ◽  
Oscar Cirioni ◽  
Federico Mocchegiani ◽  
Fiorenza Orlando ◽  
...  
Keyword(s):  
Staphylococcus Epidermidis ◽  
Vascular Graft ◽  
Graft Infection ◽  
Vascular Graft Infection ◽  
Prophylactic Agent ◽  
Temporin A
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