Membrane-Membrane Interaction and Free Energy of Multilayer Membrane System

2004 ◽  
Author(s):  
Takao Yamamoto
Keyword(s):  
Free Energy ◽  
Membrane System ◽  
Membrane Interaction ◽  
Multilayer Membrane

Modelling of Drug Penetration into Human Skin Using a Multilayer Membrane System

1995 ◽  
Vol 8 (3) ◽  
pp. 119-129 ◽  
Author(s):  
Reinhard Neubert ◽  
Wolfgang Wohlrab ◽  
Christina Bendas
Keyword(s):  
Human Skin ◽  
Membrane System ◽  
Drug Penetration ◽  
Multilayer Membrane

A multilayer membrane system for modelling drug penetration into skin

1991 ◽  
Vol 75 (1) ◽  
pp. 89-94 ◽  
Author(s):  
Reinhard Neubert ◽  
Christina Bendas ◽  
Wolfgang Wohlrab ◽  
Birgit Gienau ◽  
Walter Fürst
Keyword(s):  
Membrane System ◽  
Drug Penetration ◽  
Multilayer Membrane

Release of Urea from Semisolid Formulations Using a Multilayer Membrane System

1997 ◽  
Vol 23 (3) ◽  
pp. 253-257 ◽  
Author(s):  
M. T. Knorst ◽  
R. Neubert ◽  
W. Wohlrab
Keyword(s):  
Membrane System ◽  
Multilayer Membrane

scholarly journals Fractionation of Tilapia By-Product Protein Hydrolysate Using Multilayer Configuration of Ultrafiltration Membrane

Processes ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 446
Author(s):  
Jumardi Roslan ◽  
Siti Mazlina Mustapa Kamal ◽  
Khairul Faezah Md. Yunos ◽  
Norhafizah Abdullah
Keyword(s):  
Biological Activity ◽  
Salt Concentration ◽  
Large Scale ◽  
Protein Hydrolysate ◽  
Membrane System ◽  
Feed Solution ◽  
Permeate Flux ◽  
Fractionation Process ◽  
Dead End ◽  
Multilayer Membrane

Production of small-sized peptides is significant because of their health benefits. Ultrafiltration (UF) membrane provides an effective fractionation of small-sized peptides on a large scale. Thus, the present study was aimed to evaluate the performance of multilayer UF membrane in fractionating tilapia fish by-product (TB) protein hydrolysate by observing the permeate flux, peptide transmission, and peptide distribution under different stirring speed, pH of feed solution, and salt concentration (NaCl). The fractionation process was carried out using a dead-end UF membrane system that consists of a stack of two membrane sheets with different (10/5 kDa) and similar (5/5 kDa) pore sizes in one device. The highest permeate flux (10/5 kDa–39.5 to 47.3 L/m2.h; 5/5 kDa– 15.8 to 20.3 L/m2.h) and peptide transmission (10/5 kDa–51.8 to 61.0%; 5/5 kDa–18.3 to 23.3%) for both multilayer membrane configurations were obtained at 3.0 bar, 600 rpm, pH 8, and without the addition of salt. It was also found that the permeates were enriched with small-size peptides (<500 Da) with a concentration of 0.58 g/L (10/5 kDa) and 0.65 g/L (5/5 kDa) as compared to large-sized peptides (500–1500 Da) with concentration of 0.56 g/L (10/5 kDa) and 0.36 g/L (5/5 kDa). This might indicate the enrichment of small-size peptides through the multilayer membrane which could potentially enhance the biological activity of the protein hydrolysate fraction.

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