scholarly journals Role of growth factors in rabbit articular cartilage repair by chondrocytes in agarose

2001 ◽  
Vol 9 ◽  
pp. S48-S54 ◽  
Author(s):  
J. Weisser ◽  
B. Rahfoth ◽  
A. Timmermann ◽  
T. Aigner ◽  
R. Bräuer ◽  
...  
Keyword(s):  
Growth Factors ◽  
Articular Cartilage ◽  
Cartilage Repair ◽  
Articular Cartilage Repair ◽  
Rabbit Articular Cartilage

scholarly journals Insulin-like growth factor-1 in articular cartilage repair for osteoarthritis treatment

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Caining Wen ◽  
Limei Xu ◽  
Xiao Xu ◽  
Daping Wang ◽  
Yujie Liang ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Growth Factor ◽  
Cartilage Repair ◽  
Critical Issue ◽  
Delivery Systems ◽  
Chondrocyte Apoptosis ◽  
Insulin Like Growth Factor ◽  
Articular Cartilage Repair ◽  
Osteoarthritis Treatment

AbstractArticular cartilage repair is a critical issue in osteoarthritis (OA) treatment. The insulin-like growth factor (IGF) signaling pathway has been implicated in articular cartilage repair. IGF-1 is a member of a family of growth factors that are structurally closely related to pro-insulin and can promote chondrocyte proliferation, enhance matrix production, and inhibit chondrocyte apoptosis. Here, we reviewed the role of IGF-1 in cartilage anabolism and catabolism. Moreover, we discussed the potential role of IGF-1 in OA treatment. Of note, we summarized the recent progress on IGF delivery systems. Optimization of IGF delivery systems will facilitate treatment application in cartilage repair and improve OA treatment efficacy.

scholarly journals Articular cartilage repair: the role of bone morphogenetic proteins

2002 ◽  
Vol 26 (3) ◽  
pp. 131-136 ◽  
Author(s):  
Pecina M. ◽  
Jelic M. ◽  
Martinovic S. ◽  
Haspl M. ◽  
Vukicevic S.
Keyword(s):  
Articular Cartilage ◽  
Cartilage Repair ◽  
Bone Morphogenetic Proteins ◽  
Articular Cartilage Repair

scholarly journals Exogenous bFGF promotes articular cartilage repair via up-regulation of multiple growth factors

2013 ◽  
Vol 21 (10) ◽  
pp. 1567-1575 ◽  
Author(s):  
X. Li ◽  
G. Su ◽  
J. Wang ◽  
Z. Zhou ◽  
L. Li ◽  
...  
Keyword(s):  
Growth Factors ◽  
Articular Cartilage ◽  
Cartilage Repair ◽  
Articular Cartilage Repair
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