scholarly journals Analysis of rabbit articular cartilage repair after chondrocyte implantation using optical coherence tomography

2003 ◽  
Vol 11 (2) ◽  
pp. 111-121 ◽  
Author(s):  
C.W Han ◽  
C.R Chu ◽  
N Adachi ◽  
A Usas ◽  
F.H Fu ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Articular Cartilage ◽  
Cartilage Repair ◽  
Optical Coherence ◽  
Articular Cartilage Repair ◽  
Chondrocyte Implantation ◽  
Rabbit Articular Cartilage

A Systematic Review of Reporting of Rehabilitation in Articular-Cartilage-Repair Studies of Third-Generation Autologous Chondrocyte Implantation in the Knee

2014 ◽  
Vol 23 (3) ◽  
pp. 182-191 ◽  
Author(s):  
Philip Bright ◽  
Karen Hambly
Keyword(s):  
Articular Cartilage ◽  
Cartilage Repair ◽  
Autologous Chondrocyte Implantation ◽  
Evidence Synthesis ◽  
Third Generation ◽  
Articular Cartilage Repair ◽  
U Statistics ◽  
Chondrocyte Implantation ◽  
The Individual ◽  
Autologous Chondrocyte

Context:Autologous chondrocyte implantation (ACI) is a tissue-engineered surgical technique initially developed for articular cartilage repair of isolated chondral lesions of the knee. Third-generation techniques (ACI3) are now available that deliver autologous cultured chondrocytes into the defect using cell scaffolds. The successful outcomes of these techniques have some dependency on presurgical and postsurgical patient rehabilitation.Objectives:To determine if the standard of reporting for rehabilitation has improved in ACI3 studies; previous reviews in this field recommended describing the detail of this rehabilitation and patient compliance as integral elements.Evidence Acquisition:A computerized search was performed in March 2013. Criteria for inclusion were any studies that evaluated or described the process of ACI3 in the knee and subsequent rehabilitation. The modified Coleman Methodology Score (CMS) was used to rate the standard of reporting of rehabilitation and surgical procedures; review articles were also evaluated for quality using the Strength of Recommendation Taxonomy (SORT). Mean scores, odds ratios, 95% confidence intervals, and Mann-Whitney U statistics were calculated.Evidence Synthesis:An improvement in mean CMS was seen compared with previous reviews, but rehabilitation reporting scores were lower than their surgical equivalent; significant association was seen between studies with rehabilitator involvement and high scores in the individual CMS rehabilitation element. Predominant SORT scores of 2A indicated medium strength of recommendation.Conclusions:The CMS provides a general overview of methodological quality, but a more specialized tool to report on the quantitative and qualitative aspects of the rehabilitation process would help raise the standards. It is recommended that rehabilitation therapists be included as key members of research teams and be involved in the design, implementation, and reporting of future studies.

scholarly journals Role of growth factors in rabbit articular cartilage repair by chondrocytes in agarose

2001 ◽  
Vol 9 ◽  
pp. S48-S54 ◽  
Author(s):  
J. Weisser ◽  
B. Rahfoth ◽  
A. Timmermann ◽  
T. Aigner ◽  
R. Bräuer ◽  
...  
Keyword(s):  
Growth Factors ◽  
Articular Cartilage ◽  
Cartilage Repair ◽  
Articular Cartilage Repair ◽  
Rabbit Articular Cartilage

scholarly journals Exogenous collagen-enhanced recruitment of mesenchymal stem cells during rabbit articular cartilage repair

2007 ◽  
Vol 78 (6) ◽  
pp. 845-855 ◽  
Author(s):  
Mitsuhiko Kubo ◽  
Shinji Imai ◽  
Mineko Fujimiya ◽  
Eiji Isoya ◽  
Kosei Ando ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Articular Cartilage ◽  
Cartilage Repair ◽  
Articular Cartilage Repair ◽  
Rabbit Articular Cartilage

scholarly journals The Functions of BMP3 in Rabbit Articular Cartilage Repair

2015 ◽  
Vol 16 (11) ◽  
pp. 25934-25946 ◽  
Author(s):  
Zhe Zhang ◽  
Wenyu Yang ◽  
Yiting Cao ◽  
Yanping Shi ◽  
Chen Lei ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Cartilage Repair ◽  
Articular Cartilage Repair ◽  
Rabbit Articular Cartilage
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