scholarly journals Morphological analysis of articular cartilage biopsies from a randomized, clinical study comparing the effects of 500–730kDa sodium hyaluronate (Hyalgan®) and methylprednisolone acetate on primary osteoarthritis of the knee

2001 ◽  
Vol 9 (4) ◽  
pp. 371-381 ◽  
Author(s):  
D.D. Guidolin ◽  
I.Pasquali Ronchetti ◽  
E. Lini ◽  
D. Guerra ◽  
L. Frizziero
2014 ◽  
Vol 32 (1) ◽  
pp. 10-16 ◽  
Author(s):  
Umberto Romeo ◽  
Fabrizio Libotte ◽  
Gaspare Palaia ◽  
Alexandros Galanakis ◽  
Gianfranco Gaimari ◽  
...  

2005 ◽  
Vol 66 (1) ◽  
pp. 48-53 ◽  
Author(s):  
Aimie J. Doyle ◽  
Allison A. Stewart ◽  
Peter D. Constable ◽  
Jo Ann C. Eurell ◽  
David E. Freeman ◽  
...  

2019 ◽  
Vol 72 (11-12) ◽  
pp. 339-345
Author(s):  
Natasa Zdravkovic ◽  
Jovana Bradic ◽  
Jelena Zivic ◽  
Berislav Vekic ◽  
Sergey Bolevich ◽  
...  

Introduction. Despite the high incidence of hemorrhoidal disease and the widespread use of numerous topical preparations, there is still a lack of information regarding their efficacy. Therefore, the aim of this study was to assess the efficacy and tolerability of a new topical medical preparation containing sodium hyaluronate, calendula extract, hamamelis extract and mentha piperita essential oil as major components. Material and Methods. This prospective double-blind randomized clinical study included 49 patients with a diagnosis of hemorrhoidal disease. The patients were randomly assigned to two groups: Avaricon? group that included patients who applied 0.20% Avaricon? Hemor and a placebo group who applied placebo during 2 weeks. The effects of Avaricon? Hemor on the symptoms of hemorrhoidal disease, its safety, tolerability as well as compliance and adherence of study patients were analyzed. Results. Our results showed that Avaricon? Hemor was significantly superior to placebo in controlling most symptoms of hemorrhoidal disease. Conclusion. The tested medical agent showed to be effective with good tolerability and safety profile indicating its possible use in various therapeutic protocols in the management of hemorrhoidal disease.


1993 ◽  
Vol 42 (2) ◽  
pp. 653-657
Author(s):  
Yasuhide Taniguchi ◽  
Kunio Tomonaga ◽  
Nobuhisa Uematsu ◽  
Yoshihiro Yabe ◽  
Masahiko Okumura ◽  
...  

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