Molecular biology in respiratory disease

1989 ◽  
Vol 76 (4) ◽  
pp. 343-352
Author(s):  
R. A. Stockley
Keyword(s):  
Molecular Biology ◽  
Respiratory Disease

scholarly journals Molecular biology and respiratory disease. I-- Basic principles.

Thorax ◽  
1990 ◽  
Vol 45 (1) ◽  
pp. 52-56
Author(s):  
C A Owen ◽  
R A Stockley
Keyword(s):  
Molecular Biology ◽  
Respiratory Disease ◽  
Basic Principles

Molecular Biology of PCR Testing for COVID-19 Diagnostics

2021 ◽  
Author(s):  
Vinita Chittoor-Vinod
Keyword(s):  
Molecular Biology ◽  
Respiratory Disease ◽  
Diagnostic Tests ◽  
Genetic Material ◽  
Molecular Diagnostic ◽  
Basic Principles ◽  
Asymptomatic Carriers ◽  
Diagnostic Assays ◽  
Global Pandemic ◽  
Asymptomatic Individuals

COVID-19 cases were first reported in December 2019, and since then it has spread quickly to create a global pandemic. This respiratory disease is caused by the SARS-CoV-2 virus. A major contributing factor for the fast spread of this virus is that the infectivity by the asymptomatic carriers is similar to symptomatic patients. Thus, to identify the asymptomatic individuals and to provide the essential treatment and care to COVID-19 patients, we rely heavily on diagnostic assays. Efficient, reproducible and accessible diagnostic tests are crucial in combatting a pandemic. Currently, there are few key detection tests which have been successfully employed to field-use. However, there are constant efforts to enhance their efficacy and accessibility. This chapter aims at explaining the basic principles of the current molecular diagnostic tests, which determine the presence of the virus through the detection of its genetic material. This chapter will aid the readers in understanding the basic workings of these molecular diagnostic tests.

Vaccination for respiratory immunity: latest developments

2009 ◽  
Vol 10 (2) ◽  
pp. 155-158
Author(s):  
Richard Harland
Keyword(s):  
Immune Response ◽  
Molecular Biology ◽  
Immune Responses ◽  
Respiratory Disease ◽  
Dna Immunization ◽  
Optimal Method ◽  
Deletion Mutations

AbstractAdvances over the last 20 years in immunology and molecular biology have provided many new tools for identifying the important antigens and new ways to achieve the appropriate immune responses to these antigens. These provide many more options to achieve the best immune response from deletion mutations, subunit antigens, vectors or DNA immunization. These tools are being adopted to screen, discover and produce the appropriate antigens and to deliver them by the optimal method and with novel adjuvants to achieve the appropriate immune response. These developments will result in vaccines for respiratory disease that are safer and more efficacious, and provide greater flexibility for use and administration.

scholarly journals Molecular biology and respiratory disease. 4. Cancer genes.

Thorax ◽  
1990 ◽  
Vol 45 (5) ◽  
pp. 409-413
Author(s):  
K Sikora ◽  
G Ong
Keyword(s):  
Molecular Biology ◽  
Respiratory Disease ◽  
Cancer Genes
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