scholarly journals Protein translocation: what's the problem?

2016 ◽  
Vol 44 (3) ◽  
pp. 753-759 ◽  
Author(s):  
Robin A. Corey ◽  
William J. Allen ◽  
Ian Collinson

We came together in Leeds to commemorate and celebrate the life and achievements of Prof. Stephen Baldwin. For many years we, together with Sheena Radford and Roman Tuma (colleagues also of the University of Leeds), have worked together on the problem of protein translocation through the essential and ubiquitous Sec system. Inspired and helped by Steve we may finally be making progress. My seminar described our latest hypothesis for the molecular mechanism of protein translocation, supported by results collected in Bristol and Leeds on the tractable bacterial secretion process–commonly known as the Sec system; work that will be published elsewhere. Below is a description of the alternative and contested models for protein translocation that we all have been contemplating for many years. This review will consider their pros and cons.

2021 ◽  
Vol 46 (1) ◽  
pp. 69-79
Author(s):  
M. Blinov ◽  

Exams, being a good way to measure the academic achievement, can cause students serious psychological problems. One of the ways to eliminate stressful situations is to maximize the objectivity of students' assessment during examination testing. The article analyses the measures to reduce the subjectivity of assessment during examination testing in the context of a pandemic. Options for conducting examination testing at the university, at home and with the participation of a proctor are offered. Pros and cons of proctoring are discussed. The procedure for examination testing and the conditions for its implementation in the context of a pandemic are described in detail. The article provides a practical example of conducting an examination test in the specialty "Jurisprudence". The article considers the alternatives to examination testing. The author concludes saying that it is necessary to combine traditional and distance learning methods after the end of the pandemic period in Kazakhstan.


Author(s):  
Katina Michael ◽  
Deniz Gokyer ◽  
Samer Abbas

This chapter presents a set of scenarios involving the GoPro wearable Point of View (PoV) camera. The scenarios are meant to stimulate discussion about acceptable usage contexts with a focus on security and privacy. The chapter provides a wide array of examples of how overt wearable technologies are perceived and how they might/might not be welcomed into society. While the scenario is based at the University of Wollongong campus in Australia, the main implications derived from the fictitious events are useful in drawing out the predicted pros and cons of the technology. The scenarios are interpreted and the main thematic issues are drawn out and discussed. An in depth analysis takes place around the social implications, the moral and ethical problems associated with such technology, and possible future developments with respect to wearable devices.


2019 ◽  
Vol 25 (1) ◽  
pp. 17-36
Author(s):  
Lailatur Rahmi

AbstractThe Reference Service is one of the library services designed to assist the users of the library in meeting their information needs. The development of reference services is, especially, important in the tertiary educational institutions. The growth of incredible information and technological developments decline the number of users of the printed reference collections ; there are pros and cons when it comes to the technology that, supposedly, make things easier and practical. The study aims to describe the usefulness of communication media in virtual reference services at the University of Indonesia Library. The results of the study illustrate that the University of Indonesia library has provided communication media as access to virtual reference services through various communication media due to the influence of the development of technological sophistication  


2017 ◽  
Vol 4 (4) ◽  
pp. 107 ◽  
Author(s):  
Carmen Valero-Garcés

The University of Alcalá, Madrid, offers a 1-year Master’s Degree course in Public Service Interpreting and Translation (PSIT). The curriculum is based on the principle of cross-fertilization of the three main parameters of training, research and practice. The implementation of this principle in practice means alliances and cooperation with all stakeholders that in one way or other participate in the translation and interpreting (T&I) working environment. Special attention needs to be paid to the job market and to the real recruitment conditions, as well as to the requirements for professional translators and interpreters. In the present article the focus is on one of the main parameters of a successful curriculum, i.e. practice in training, or internships. Internships serve as an introduction to the workplace. The pros and cons of the experience are discussed from three points of view: that of trainers, institutions and students. The informatikon obtained from all three parties has revealed both strong and weak points of the process, but it helped to know what happened outside and inside the classroom for both sides—PSIT students and trainers, on the one hand, and providers of public services on the other. Conclusions serve as feedback and are taken into account when trying to improve educational aspects.


2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Patti Sherbaniuk

Hlinka, Michael.  Follow Your Money: Who Gets it, Who Spends It, Where Does it Go?  Illus. Kevin Sylvester. Annick Press, New York, 2013. Print.Follow Your Money is a fairly basic yet informative examination of the economy and its complexities, aimed at older kids and teens. The book starts off with a quick synopsis of the “spider web” of the economy and a brief rundown of the history of money and the concept of profit.  The author then breaks down the costs of various activities (a bus ride for example) and objects (baseball caps, sneakers), from raw materials to manufacturing costs, labour, transport, store markups, profits, etc. The author (a CBC commentator on business) is clever in what he has chosen, selecting objects and activities that are of interest to older kids and teens (computers, designer jeans, chocolate, cell phones, music, etc.).  There are also a couple of pages on fuel and its importance to the economy. The book then takes a brief look at banking and the pros and cons of credit and debit cards, and then finishes with resource suggestions for additional information and an index.The cost breakdowns may be too numerous and a little dry for some readers (depending on their interest and attention level), but they are a very effective method of getting the reader to think about where things come from, how various economic factors affect prices, and who gets the profits. The author includes interesting sidebars of historical facts and trivia about particular subjects- tea, for example, or disposable bags-adding a bit of humour in the process.  The illustrations are colourful and quirky and help clarify the points the author is making.Ideal for upper elementary and teen readers.Highly recommended:  4 out of 4 stars Reviewer: Patti SherbaniukPatti is a Liaison Librarian at the Winspear School of Business at the University of Alberta. She holds a BA in English and an MLIS, both from the University of Alberta. She is passionate about food, travel, the arts and reading books of all shapes and sizes.


1989 ◽  
Vol 28 (04) ◽  
pp. 281-284 ◽  
Author(s):  
D. Protti

Abstract:This paper discusses the teaching of a course which simulates what a hospital goes through when it conceptualizes the need for a Hospital Information System, identifies its goals and objectives for the system, prepares a Request for Proposal (RFP), and selects a particular system. The course is. taught entirely in simulation and role playing modes. Students are taken on site visits, vendors come to the University to demonstrate their systems, and consultants are brought in to give advice. The pros and cons of this particular style of teaching are discussed.


2020 ◽  
Vol 217 (9) ◽  
Author(s):  
Stephanie Houston

COVID-19 abruptly halted scientific conferences and seminars in mid-March, forcing the scientific community to either postpone or adapt to a virtual format. We caught up with Carla V. Rothlin, Elina I. Zúñiga, Hongbo Chi, Rino Rappuoli, and Matthew Krummel to find out about the pros and cons of virtual conferences and seminars and how these could change the nature of scientific conferences. Carla (CVR) and Elina (EIZ) established Global ImmunoTalks in April this year; Hongbo (HC) helped organize the Immunometabolism Mini-Symposia series in May and June; Rino (RR) was one of the scientific organizers of the Transforming Vaccinology Keystone, which moved to a virtual format in June; and Matthew (MK) has been organizing Eco Seminars at the University of California, San Francisco since 2019.


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