Comparison of human low-molecular-weight RNA from normal and Crohn's disease derived blood and mesenteric, lymph node leucocytes

1984 ◽  
Vol 12 (6) ◽  
pp. 1112-1113
Author(s):  
PHILIP D. BUTCHER ◽  
CAROLYN M. STRANGE ◽  
JOHNJOE McFADDEN ◽  
JOHN HERMON-TAYLOR
2018 ◽  
Vol 13 (1) ◽  
pp. 58-66 ◽  
Author(s):  
Miranda G Kiernan ◽  
J Calvin Coffey ◽  
Kieran McDermott ◽  
Paul D Cotter ◽  
Raul Cabrera-Rubio ◽  
...  

Gut ◽  
1980 ◽  
Vol 21 (6) ◽  
pp. 507-511 ◽  
Author(s):  
E R Richens ◽  
C M Thorp ◽  
P W Bland ◽  
K R Gough

2009 ◽  
Vol 137 (5) ◽  
pp. 1736-1745 ◽  
Author(s):  
Atsushi Sakuraba ◽  
Toshiro Sato ◽  
Nobuhiko Kamada ◽  
Mina Kitazume ◽  
Akira Sugita ◽  
...  

1987 ◽  
Vol 42 (7-8) ◽  
pp. 1006-1008 ◽  
Author(s):  
Reinhard Pechan ◽  
Hans Kunert ◽  
Hans J. Gross

Crohn’s disease/small RNAs/electrophoresis Twodimensional and bidirectional electrophoretic tech­ niques previously developed for the specific detection of circular viroids and virusoids in plant material were used to analyze preparations of low molecular weight RNA from the granulomatous bowel tissue of patients with Crohn’s disease and from corresponding tissue of healthy controls. A major and two minor RNA species of about 300 nu­ cleotides length were detected in RNA samples from eight Crohn’s disease patients and not in those from three healthy controls. It remains to be established whether these disease-associated RNAs with viroid-like electrophoretic properties play a causative role in Crohn’s disease.


1975 ◽  
Vol 148 (3) ◽  
pp. 417-423 ◽  
Author(s):  
S I Chavin ◽  
S M Johnson ◽  
A Holliman

Plasma membranes from pig mesenteric lymph-node lymphocytes contain a large number of polypeptide chains ranging in molecular weight from 20,000 to greater than 470,000, with a major component of 46,000. There are approx. 12-15 glycoproteins. The membranes contain immunoglobulin G, which comprises 0.6% of the total protein. Immunoglobulin M is also detected, but has not been accurately quantified for technical reasons. Possible origins of the membrane-associated immunoglobulin are briefly discussed. It is concluded that the immunoglobulin is probably associated with the plasma membrane in the intact cell.


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