The electrophoretic analysis of low molecular weight nucleic acids from Crohn's disease tissues in the search for an unconventional small infections agent

1986 ◽  
Vol 88 (1-2) ◽  
pp. 113-120 ◽  
Author(s):  
P. D. Butcher ◽  
J. J. McFadden ◽  
J. Hermon-Taylor
Keyword(s):  
Molecular Weight ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Nucleic Acids ◽  
Electrophoretic Analysis ◽  
Low Molecular Weight

Are Small RNAs Associated with Crohn’s Disease?

1987 ◽  
Vol 42 (7-8) ◽  
pp. 1006-1008 ◽  
Author(s):  
Reinhard Pechan ◽  
Hans Kunert ◽  
Hans J. Gross
Keyword(s):  
Molecular Weight ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Small Rnas ◽  
Plant Material ◽  
Low Molecular Weight ◽  
Causative Role ◽  
Healthy Controls ◽  
Specific Detection

Crohn’s disease/small RNAs/electrophoresis Twodimensional and bidirectional electrophoretic tech­ niques previously developed for the specific detection of circular viroids and virusoids in plant material were used to analyze preparations of low molecular weight RNA from the granulomatous bowel tissue of patients with Crohn’s disease and from corresponding tissue of healthy controls. A major and two minor RNA species of about 300 nu­ cleotides length were detected in RNA samples from eight Crohn’s disease patients and not in those from three healthy controls. It remains to be established whether these disease-associated RNAs with viroid-like electrophoretic properties play a causative role in Crohn’s disease.

scholarly journals Characterization of the structure and composition of gecko adhesive setae

2005 ◽  
Vol 3 (8) ◽  
pp. 441-451 ◽  
Author(s):  
N.W Rizzo ◽  
K.H Gardner ◽  
D.J Walls ◽  
N.M Keiper-Hrynko ◽  
T.S Ganzke ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Molecular Weight ◽  
Electrophoretic Analysis ◽  
Low Molecular Weight ◽  
X Ray Diffraction ◽  
X Ray ◽  
Pattern Characteristic ◽  
Additional Protein ◽  
Adhesive Materials

The ability of certain reptiles to adhere to vertical (and hang from horizontal) surfaces has been attributed to the presence of specialized adhesive setae on their feet. Structural and compositional studies of such adhesive setae will contribute significantly towards the design of biomimetic fibrillar adhesive materials. The results of electron microscopy analyses of the structure of such setae are presented, indicating their formation from aggregates of proteinaceous fibrils held together by a matrix and potentially surrounded by a limiting proteinaceous sheath. Microbeam X-ray diffraction analysis has shown conclusively that the only ordered protein constituent in these structures exhibits a diffraction pattern characteristic of β-keratin. Raman microscopy of individual setae, however, clearly shows the presence of additional protein constituents, some of which may be identified as α-keratins. Electrophoretic analysis of solubilized setal proteins supports these conclusions, indicating the presence of a group of low-molecular-weight β-keratins (14–20 kDa), together with α-keratins, and this interpretation is supported by immunological analyses.

RNA-targeting low-molecular-weight fluorophores for nucleoli staining: synthesis, in silico modelling and cellular imaging

2021 ◽  
Author(s):  
Atanas Kurutos ◽  
Jasmina Nikodinovic Runic ◽  
Aleksandar M Veselinović ◽  
Jovana B. Veselinović ◽  
Fadhil Suliman Kamounah ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Molecular Docking ◽  
Nucleic Acids ◽  
In Silico ◽  
Photophysical Properties ◽  
Low Molecular Weight ◽  
Carbocyanine Dyes ◽  
Imaging Application ◽  
Rna Targeting ◽  
Low Molecular Weight Compounds

Herein we present our work on the synthesis, investigation on photophysical properties, interactions with nucleic acids, molecular docking, and imaging application of three carbocyanine dyes. Described low-molecular-weight compounds were found...

scholarly journals Global Role of Low Molecular Weight Nucleic Acids in Biological Systems

2020 ◽  
pp. 5-10
Author(s):  
Zemskov V.M. ◽  
Neymann V. ◽  
Zemskov A. M. ◽  
Pronko K. N.
Keyword(s):  
Molecular Weight ◽  
Nucleic Acids ◽  
Biological Systems ◽  
Consistent Pattern ◽  
Low Molecular Weight ◽  
Human Being ◽  
Entire Life ◽  
Lower Organism

Some considerations and reports are made regarding personal scientific developments carried out by author V.M. Zemskov in partnership with colleagues team and my close colleague prof. Zemskov A.M. for many years, specifically, 50 years. This is a problem, to which almost entire life has been devoted. It relates to a completely new global consistent pattern that we managed to stumble upon in those distant years, and that is implemented in any biological systems -whether it’s a higher or a lower organism, a human being, or various microbial and cellular populations. Realized by low molecular weight RNA or oligonucleotides of RNA.

Transfer of immunologic memory in man with low molecular weight nucleic acids

1966 ◽  
Vol 69 (5) ◽  
pp. 954-955 ◽  
Author(s):  
Philip Fireman ◽  
Zaky H. Haddad ◽  
Mary Boesman ◽  
David Gitlin
Keyword(s):  
Molecular Weight ◽  
Nucleic Acids ◽  
Low Molecular Weight ◽  
Immunologic Memory

scholarly journals Studies on several basic conditions of electrophoretic analysis of low molecular weight polypeptides in usine and plasma.

1985 ◽  
Vol 29 (4) ◽  
pp. 237-243
Author(s):  
Kazumi Okuyama ◽  
Nobuyuki Honma ◽  
Kazuko Hasegawa ◽  
Hiroshi Sugano ◽  
Iku Sugano ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Electrophoretic Analysis ◽  
Low Molecular Weight
Sign in / Sign up

Export Citation Format

Share Document