Plant cytokinin signalling

2015 ◽  
Vol 58 ◽  
pp. 13-27 ◽  
Author(s):  
Erika A. Keshishian ◽  
Aaron M. Rashotte
Keyword(s):  
Signalling Pathway ◽  
Plant Responses ◽  
Response Regulators ◽  
Embryo Patterning ◽  
Wide Range ◽  
Isopentenyl Adenine ◽  
Almost All ◽  
Crucial Part ◽  
Signalling Process

Cytokinin is an essential plant hormone that is involved in a wide range of plant growth and developmental processes which are controlled through its signalling pathway. Cytokinins are a class of molecules that are N6-substituted adenine derivatives, such as isopentenyl adenine, and trans- and cis-zeatin, which are common in most plants. The ability to perceive and respond to cytokinin occurs through a modified bacterial two-component pathway that functions via a multi-step phosphorelay. This cytokinin signalling process is a crucial part of almost all stages of plant life, from embryo patterning to apical meristem regulation, organ development and eventually senescence. The cytokinin signalling pathway involves the co-ordination of three types of proteins: histidine kinase receptors to perceive the signal, histidine phosphotransfer proteins to relay the signal, and response regulators to provide signal output. This pathway contains both positive and negative elements that function in a complex co-ordinated manner to control cytokinin-regulated plant responses. Although much is known about how this cytokinin signal is perceived and initially regulated, there are still many avenues that need to be explored before the role of cytokinin in the control of plant processes is fully understood.

Potential Role of Endophytes for Sustainable Environment

2019 ◽  
pp. 78-95
Author(s):  
Zubair A. Dar ◽  
Bhat Rifat ◽  
Javeed I. A. Bhat ◽  
Asma Absar Bhatti ◽  
Shamsul Haq ◽  
...  
Keyword(s):  
Plant Growth ◽  
Organic Contaminants ◽  
Plant Stress ◽  
Plant Responses ◽  
Sustainable Environment ◽  
Plant Growth Promoting ◽  
Plant Stress Tolerance ◽  
Growth Promoting ◽  
Almost All

Endophytes are symptomless fungal and bacterial microorganisms found in almost all living plants. They are vital components of plant microbiomes. Endophytes affect plant growth and plant responses to pathogens, herbivores, and environmental change by producing a range of natural products having antifungal, antibacterial, and insecticidal properties. Endophytes have shown particular promise in agriculture particularly as beneficial crop inoculants and are known to enhance abiotic and biotic plant stress tolerance by increasing tolerance to drought and water stress, as well as tolerance to high temperature and high salinity. A better understanding of their plant growth-promoting mechanisms could simplify higher production of energy crops in a more sustainable manner even on marginal land and feed stocks for industrial processes, thus contribute to avoiding conflicts between food and energy production Many endophytes can be exploited to improve the efficiency of phytoremediation as they are found to be resistant to heavy metals and capable of detoxifying organic contaminants.

scholarly journals Host-microbiome coevolution promotes cooperation in a rock-paper-scissor dynamic

2019 ◽  
Author(s):  
Ohad Lewin-Epstein ◽  
Lilach Hadany
Keyword(s):  
Computational Modeling ◽  
Potential Role ◽  
Evolution Of Cooperation ◽  
Host Behavior ◽  
Wide Range ◽  
Forms Of Life ◽  
New Perspective ◽  
Almost All ◽  
And Behavior

AbstractCooperation is a fundamental behavior observed in all forms of life. The evolution of cooperation has been widely studied, but almost all theories focused on the cooperating individual and its genes. We suggest a different approach, taking into account the microbes carried by the interacting individuals. Accumulating evidence reveal that microbes can affect their host wellbeing and behavior, yet hosts can evolve mechanisms to resist the manipulations of their microbes. We thus propose that coevolution of microbes with their hosts may favor microbes that induce their host to cooperate. Using computational modeling, we show that microbe-induced cooperation can evolve and be maintained in a wide range of conditions, including when facing hosts’ resistance to the microbial effect. We find that host-microbe coevolution leads the population to a rock-paper-scissors dynamic, that enables maintenance of cooperation in a polymorphic state. This theory may help explain occurrences of cooperation in a wide variety of organisms, including in cases that are difficult to explain by current theories. In addition, this study provides a new perspective on the coevolution of hosts and their microbiome, emphasizing the potential role of microbes in shaping their host behavior.

Nanomaterial: A Sustainable Way to Fight against COVID-19

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Atish K. Maldhure
Keyword(s):  
Infectious Disease ◽  
Materials Science ◽  
Review Article ◽  
Causative Pathogen ◽  
Science And Engineering ◽  
Engineering Sciences ◽  
Wide Range ◽  
Materials Science And Engineering ◽  
Almost All

Abstract:: Nanotechnology is multidisciplinary science which deals with physics, chemistry, materials science, and engineering sciences. The applications of Nanotechnology cover almost all the branches of science and technology. In late 2019, SARS-CoV-2 virus becomes caused to infection of coronavirus infectious disease (COVID-19). The outbreak of 2019 coronavirus disease (COVID-19) becomes challenge to Hospitals and laboratories, due to the large number samples comes for testing the presence of the causative pathogen. Many Scientist and researchers are devotedly working on to find out rapid immunodiagnostic methods to find positive cases. Nano based drugs offer a new therapeutic scheme against the wide range of bacterial pathogens. In this review article, I try to focus on the role of nanomaterial fighting against COVID-19.

The function of S-nitrosothiols during abiotic stress in plants

2019 ◽  
Vol 70 (17) ◽  
pp. 4429-4439 ◽  
Author(s):  
Juan C Begara-Morales ◽  
Mounira Chaki ◽  
Raquel Valderrama ◽  
Capilla Mata-Pérez ◽  
Maria N Padilla ◽  
...  
Keyword(s):  
Abiotic Stress ◽  
Current Knowledge ◽  
Stomatal Closure ◽  
Cysteine Residue ◽  
Detection Methods ◽  
Plant Responses ◽  
Wide Range ◽  
Signaling Events

Abstract Nitric oxide (NO) is an active redox molecule involved in the control of a wide range of functions integral to plant biology. For instance, NO is implicated in seed germination, floral development, senescence, stomatal closure, and plant responses to stress. NO usually mediates signaling events via interactions with different biomolecules, for example the modulation of protein functioning through post-translational modifications (NO-PTMs). S-nitrosation is a reversible redox NO-PTM that consists of the addition of NO to a specific thiol group of a cysteine residue, leading to formation of S-nitrosothiols (SNOs). SNOs are more stable than NO and therefore they can extend and spread the in vivo NO signaling. The development of robust and reliable detection methods has allowed the identification of hundreds of S-nitrosated proteins involved in a wide range of physiological and stress-related processes in plants. For example, SNOs have a physiological function in plant development, hormone metabolism, nutrient uptake, and photosynthesis, among many other processes. The role of S-nitrosation as a regulator of plant responses to salinity and drought stress through the modulation of specific protein targets has also been well established. However, there are many S-nitrosated proteins that have been identified under different abiotic stresses for which the specific roles have not yet been identified. In this review, we examine current knowledge of the specific role of SNOs in the signaling events that lead to plant responses to abiotic stress, with a particular focus on examples where their functions have been well characterized at the molecular level.

scholarly journals Muramyldipeptide - based compounds in current medicine: focus on glucosaminylmuramyl dipeptide

2019 ◽  
Vol 91 (12) ◽  
pp. 122-127 ◽  
Author(s):  
E A Ushkalova ◽  
S K Zyryanov ◽  
K E Zatolochina
Keyword(s):  
High Efficiency ◽  
Biological Effects ◽  
Immunosuppressive Drugs ◽  
Trade Name ◽  
Wide Range ◽  
Oncological Diseases ◽  
Adults And Children ◽  
Almost All ◽  
Based Medicine

The role of immune mechanisms in the pathogenesis of almost all human diseases shown in recent decades, increase in antibiotic resistance and secondary immunodeficiency, aging of the population and widespread use of immunosuppressive drugs and procedures suggest a wider use of immunomodulators in current clinical practice, but the use of most of them limits the lack of knowledge. The most promising compounds for the development as immunomodulating agents and adjuvants for a wide range of vaccines are low molecular weight fragments of peptidoglycan - muramylpeptides. The article describes the mechanisms of action of muramylpeptides, their biological effects and properties of medicines developed on their basis. Special emphasis is placed to glucosaminylmuramyl dipeptide registered in the Russian Federation under the trade name Likopid, which is currently the best - studied drug in its group. The results of Likopid studies when used as a prophylactic and therapeutic agent for infections of various localization in adults and children, for oncological diseases and complications of chemotherapy and radiation therapy, psoriasis, atopic and other diseases are presented. It is emphasized that in diseases associated with human papillomavirus and plaque psoriasis, according to current criteria of evidence - based medicine, Likopid should be classified as drug with level A efficacy (high efficiency in 80-100% of patients). High safety of Likopid in adults and children, including newborns, is noted.

scholarly journals About the issue of the “Population and Economics” devoted to interaction of population and the economy in geographical space

2019 ◽  
Vol 3 (1) ◽  
pp. 1-3
Author(s):  
Tatyana Nefedova
Keyword(s):  
Wide Range ◽  
Almost All ◽  
Geographical Space

This issue was prepared mainly by geographers. Almost all of the articles are one way or another devoted to the role of space in the development of society, or rather, a wide range of relations between the population and the economy through space.

scholarly journals Activin/Nodal signalling before implantation: setting the stage for embryo patterning

2014 ◽  
Vol 369 (1657) ◽  
pp. 20130539 ◽  
Author(s):  
Costis Papanayotou ◽  
Jérôme Collignon
Keyword(s):  
Transforming Growth Factor Beta ◽  
Target Genes ◽  
Transforming Growth Factor ◽  
Embryonic Stem ◽  
Signalling Pathway ◽  
Loss Of Function ◽  
Embryo Patterning ◽  
Developmental Progression ◽  
Growth Factor Beta

Activins and Nodal are members of the transforming growth factor beta (TGF-β) family of growth factors. Their Smad2/3-dependent signalling pathway is well known for its implication in the patterning of the embryo after implantation. Although this pathway is active early on at preimplantation stages, embryonic phenotypes for loss-of-function mutations of prominent components of the pathway are not detected before implantation. It is only fairly recently that an understanding of the role of the Activin/Nodal signalling pathway at these stages has started to emerge, notably from studies detailing how it controls the expression of target genes in embryonic stem cells. We review here what is currently known of the TGF-β-related ligands that determine the activity of Activin/Nodal signalling at preimplantation stages, and recent advances in the elucidation of the Smad2/3-dependent mechanisms underlying developmental progression.

scholarly journals Exosomes: A Key Piece in Asthmatic Inflammation

2021 ◽  
Vol 22 (2) ◽  
pp. 963
Author(s):  
José A. Cañas ◽  
José M. Rodrigo-Muñoz ◽  
Marta Gil-Martínez ◽  
Beatriz Sastre ◽  
Victoria del Pozo
Keyword(s):  
Cell Types ◽  
Donor Cells ◽  
Wide Range ◽  
Spherical Structures ◽  
Multiple Cell ◽  
Extracellular Microenvironment ◽  
Almost All ◽  
Multiple Cells ◽  
Different Sources

Asthma is a chronic disease of the airways that has an important inflammatory component. Multiple cells are implicated in asthma pathogenesis (lymphocytes, eosinophils, mast cells, basophils, neutrophils), releasing a wide variety of cytokines. These cells can exert their inflammatory functions throughout extracellular vesicles (EVs), which are small vesicles released by donor cells into the extracellular microenvironment that can be taken up by recipient cells. Depending on their size, EVs can be classified as microvesicles, exosomes, or apoptotic bodies. EVs are heterogeneous spherical structures secreted by almost all cell types. One of their main functions is to act as transporters of a wide range of molecules, such as proteins, lipids, and microRNAs (miRNAs), which are single-stranded RNAs of approximately 22 nucleotides in length. Therefore, exosomes could influence several physiological and pathological processes, including those involved in asthma. They can be detected in multiple cell types and biofluids, providing a wealth of information about the processes that take account in a pathological scenario. This review thus summarizes the most recent insights concerning the role of exosomes from different sources (several cell populations and biofluids) in one of the most prevalent respiratory diseases, asthma.

scholarly journals Ultrasonography in the diagnosis of ovarian and endometrial carcinoma

2011 ◽  
Vol 152 (47) ◽  
pp. 1887-1893
Author(s):  
Sándor Valent ◽  
Orsolya Oláh ◽  
Levente Sára ◽  
Attila Pajor ◽  
Zoltán Langmár
Keyword(s):  
Endometrial Carcinoma ◽  
Significant Role ◽  
Transvaginal Ultrasound ◽  
Three Dimensional ◽  
Transvaginal Sonography ◽  
Gynecological Diseases ◽  
Set Up ◽  
Almost All ◽  
Crucial Part

Transvaginal sonography has become a crucial part of the routine gynecologic examination. It offers now a great help in the diagnosis of almost all gynecological diseases. Transvaginal ultrasound means the first step in the diagnosis of the first two most common gynecological malignancies, and in many cases we are able to set up a diagnosis of its own. The purpose of this article is to emphasize the significant role of transvaginal ultrasonography in the diagnosis of these two dieseases mentioned above, with summarizing the latest developments regarding the capabilities of sonography (Doppler-technique, three-dimensional ultrasonograpy). Orv. Hetil., 2011, 152, 1887–1893.

scholarly journals Observational Study to evaluate the role of Ultrasonography and X-Ray in Urinary Disease

2020 ◽  
Vol 11 (1) ◽  
pp. 1206-1209
Author(s):  
Amit Kumar Singh ◽  
Mishra S.S. ◽  
Arun Kumar Dwivedi
Keyword(s):  
Urine Analysis ◽  
Histopathological Examination ◽  
Radiological Examination ◽  
Urinary System ◽  
X Ray ◽  
Physical Problems ◽  
Wide Range ◽  
Contrast Ultrasonography ◽  
Almost All

Urinary diseases are very common in our society which system constitutes kidneys ureters urinary bladder and urethra various abnormalities occur in these organs due to many reasons like infection inflammation metabolic abnormalities neoplastic changes trauma etc. these abnormalities lead to various physical problems ending into death many times the abnormalities of urinary system can be diagnosed by hematological examination urine analysis radiological examination and histopathological examination especially radiological examination provide wide range of diagnosis of disease of urinary system of almost all origin although various radiological technique like X-ray (plain and contrast) Ultrasonography CT scan MRI and many others are available but in present study X-ray (plain and contrast ) and ultrasonography were used for diagnosis of disease of urinary system because of its easy availability and affordability the diseases of urinary system has been described under the name of Mutrakrichha and Mutraghata  in ayurveda these two conditions are in fact group of clinical entities in which urination is difficult and retention is present respectively further they are divided into various subtypes these conditions resembles clinically with various types of urinary diseases early diagnosis has been the always advocated by ayurveda by virtue of this prevention and management becomes easy in the present study written informed consent has been taken from all the patients early detection of these conditions facilitates the management otherwise renal failure may complicate the condition

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