Design and fabrication of flexible glucose sensing platform toward rapid battery-free detection of hyperglycaemia

2021 ◽  
Author(s):  
Hajime Fujita ◽  
Kento Yamagishi ◽  
Wenshen Zhou ◽  
Yu Tahara ◽  
Shao Ying Huang ◽  
...  
Keyword(s):  
Health Risks ◽  
Rapid Detection ◽  
Glucose Sensing ◽  
Glucose Sensors ◽  
Postprandial Hyperglycaemia ◽  
Promising Tool ◽  
Sensing Platform

The rapid detection of postprandial hyperglycaemia is imperative for the diagnosis of diabetes and the assessment of health risks for nondiabetics. Battery-free flexible glucose sensors are a promising tool for...

scholarly journals Recent Advances in Enzymatic and Non-Enzymatic Electrochemical Glucose Sensing

Sensors ◽  
2021 ◽  
Vol 21 (14) ◽  
pp. 4672
Author(s):  
Mohamed H. Hassan ◽  
Cian Vyas ◽  
Bruce Grieve ◽  
Paulo Bartolo
Keyword(s):  
Noble Metals ◽  
Direct Electrochemistry ◽  
Glucose Sensing ◽  
Glucose Sensors ◽  
Diabetic Patients ◽  
Past Century ◽  
Industrial Sectors ◽  
Recent Advances ◽  
Wide Range ◽  
Sensitivity And Selectivity

The detection of glucose is crucial in the management of diabetes and other medical conditions but also crucial in a wide range of industries such as food and beverages. The development of glucose sensors in the past century has allowed diabetic patients to effectively manage their disease and has saved lives. First-generation glucose sensors have considerable limitations in sensitivity and selectivity which has spurred the development of more advanced approaches for both the medical and industrial sectors. The wide range of application areas has resulted in a range of materials and fabrication techniques to produce novel glucose sensors that have higher sensitivity and selectivity, lower cost, and are simpler to use. A major focus has been on the development of enzymatic electrochemical sensors, typically using glucose oxidase. However, non-enzymatic approaches using direct electrochemistry of glucose on noble metals are now a viable approach in glucose biosensor design. This review discusses the mechanisms of electrochemical glucose sensing with a focus on the different generations of enzymatic-based sensors, their recent advances, and provides an overview of the next generation of non-enzymatic sensors. Advancements in manufacturing techniques and materials are key in propelling the field of glucose sensing, however, significant limitations remain which are highlighted in this review and requires addressing to obtain a more stable, sensitive, selective, cost efficient, and real-time glucose sensor.

scholarly journals Rapid detection of Salmonella sp. in pork samples using fluorescent in situ hybridization: a comparison with VIDAS®-SLM system and ISO 6579 cultural method

2007 ◽  
Vol 59 (6) ◽  
pp. 1388-1393 ◽  
Author(s):  
M. Vieira-Pinto ◽  
M. Oliveira ◽  
F. Bernardo ◽  
C. Martins
Keyword(s):  
In Situ Hybridization ◽  
Rapid Detection ◽  
Fluorescent In Situ Hybridization ◽  
Diagnostic Assay ◽  
Promising Tool ◽  
Cultural Method ◽  
Inner Surface ◽  
Peptone Water ◽  
Pork Samples

This study reports the use of the fluorescent in situ hybridization (FISH) with Sal3 probe for Salmonella detection in swine carcasses inner surface (swab); and in the correspondent samples of ileum, ileocolic, and mandibular lymph nodes; and tonsils, after dilution (1:10) in buffered peptone water and a pre-enrichment step (37(0)C, 18h). In order to evaluate the efficiency of FISH, 235 naturally contaminated samples were simultaneously tested by the cultural method (ISO 6579) and by the Vitek Immuno Diagnostic Assay System (VIDAS®) - Salmonella (SLM) system. The cultural method identified 39 positive samples. From these, VIDAS®- SLM only detected 23. FISH identified 115 positive samples. This difference was highly significant (P<0.001). From positive samples, 32 were also confirmed by the cultural method. The results indicate FISH as a promising tool for rapid Salmonella detection in samples of pork and swine carcasses.

Non-enzymatic flexible glucose sensing platform based on nanostructured TiO2 – Au composite

2019 ◽  
Vol 837 ◽  
pp. 230-239 ◽  
Author(s):  
Katarzyna Grochowska ◽  
Jacek Ryl ◽  
Jakub Karczewski ◽  
Gerard Śliwiński ◽  
Adam Cenian ◽  
...  
Keyword(s):  
Glucose Sensing ◽  
Nanostructured Tio2 ◽  
Sensing Platform

Cuprous Oxide Films with Hollow Cubic Cage Structure for Nonenzymatic Glucose Detection

NANO ◽  
2019 ◽  
Vol 14 (04) ◽  
pp. 1950045
Author(s):  
Fang Sun ◽  
Lehong Xing ◽  
Xihui Yang ◽  
Hailiang Huang ◽  
Lina Ning
Keyword(s):  
Electrode Materials ◽  
Glucose Sensor ◽  
High Sensitivity ◽  
Fast Response ◽  
Glucose Sensing ◽  
Glucose Sensors ◽  
Cage Structure ◽  
Active Materials ◽  
Nonenzymatic Glucose Sensor ◽  
Step Procedure

In this study, CuO films with hollow cubic cages were prepared by a facile two-step procedure consisting of electrodeposition synthesis and subsequent direct calcination. First, Cu2O nanocubes were fabricated on ITO substrate through a simple electrodeposition procedure. Then, Cu2O nanocubes were converted to CuO hollow cubic cages without obvious morphological change through direct calcination. The obtained CuO cubic cages serving as active materials illustrated a favorable performance for nonenzymatic glucose sensing with high sensitivity of [Formula: see text]A[Formula: see text]mM[Formula: see text][Formula: see text]cm[Formula: see text] at a low applied potential of 0.50[Formula: see text]V, fast-response time (less than 3[Formula: see text]s), low detection limit of 1.0[Formula: see text][Formula: see text]M and wide linear range up from 2.0[Formula: see text][Formula: see text]M to 1.0[Formula: see text]mM ([Formula: see text]). Moreover, the good selectivity of the CuO cubic cages-based nonenzymatic glucose sensor against electroactive compounds such as ascorbic acid, uric acid and dopamine were also demonstrated. These good features indicate that the as-prepared CuO cubic cages can be used as promising electrode materials, which have a great potential in the development of sensitive and selective nonenzymatic glucose sensors.

Black phosphorus nanosheets for rapid microRNA detection

Nanoscale ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 5060-5064 ◽  
Author(s):  
Jie Zhou ◽  
Zhongjun Li ◽  
Ming Ying ◽  
Maixian Liu ◽  
Xiaomei Wang ◽  
...  
Keyword(s):  
Fluorescence Quenching ◽  
Rapid Detection ◽  
Black Phosphorus ◽  
Sensing Platform ◽  
Microrna Detection ◽  
First Time

Herein, for the first time, a sensitive sensing platform for rapid detection of microRNA was developed by employing black phosphorus nanosheets as the fluorescence quenching material.

scholarly journals Red-Emissive Carbon Dots for “Switch-On” Dual Function Sensing Platform Rapid Detection of Ferric Ions and l-Cysteine in Living Cells

ACS Omega ◽  
2019 ◽  
Vol 4 (7) ◽  
pp. 12575-12583 ◽  
Author(s):  
Xingxing Yang ◽  
Fangchao Cui ◽  
Rong Ren ◽  
Jiadi Sun ◽  
Jian Ji ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Rapid Detection ◽  
Living Cells ◽  
Dual Function ◽  
Ferric Ions ◽  
Sensing Platform

scholarly journals Synthesis of Ni-Co Hydroxide Nanosheets Constructed Hollow Cubes for Electrochemical Glucose Determination

Sensors ◽  
2019 ◽  
Vol 19 (13) ◽  
pp. 2938 ◽  
Author(s):  
Fengchao Sun ◽  
Shutao Wang ◽  
Yuqi Wang ◽  
Jingtong Zhang ◽  
Xinping Yu ◽  
...  
Keyword(s):  
Electrode Materials ◽  
High Efficiency ◽  
Particle Morphology ◽  
Glucose Sensing ◽  
Glucose Sensors ◽  
Molar Ratio ◽  
Glucose Determination ◽  
Lamellar Morphology ◽  
Transmission Electron ◽  
Double Transition

Hierarchical Ni-Co double transition metal hydroxide nanosheets have been explored as an effective strategy for the design of nonenzymatic glucose sensors. Ni-Co hydroxide nanosheets constructed hollow cubes were successfully synthesized by using Cu2O cubes as templates and subsequently etched by Na2S2O3 to achieve a hollow cubic structure. The molar ratio between Ni and Co was tuned by varying the precursor ratio of NiCl2 and CoCl2. It was observed by transmission electron microscopy (TEM) that the increasing Ni precursor resulted in particle morphology, and the increasing ratio of the Co precursor resulted in more lamellar morphology. The sample with the composition of Ni0.7Co0.3(OH)2 displayed the best performance for glucose sensing with high selectivity (1541 μA mM–1 cm–2), low detection limit (3.42 µM with S/N = 3), and reasonable selectivity. Similar strategies could be applied for the design of other electrode materials with high efficiency for nonenzymatic glucose determination.

Advances in Noninvasive Glucose Sensing Enabled by Photonics, Acoustics, and Microwaves

2018 ◽  
Vol 12 (1) ◽  
pp. 64-72
Author(s):  
Takuro Tajima ◽  
◽  
Masahito Nakamura ◽  
Yujiro Tanaka ◽  
Michiko Seyama
Keyword(s):  
Near Infrared ◽  
Diabetes Management ◽  
Glucose Sensing ◽  
Glucose Sensors ◽  
Optical Absorption Spectroscopy ◽  
High Quality ◽  
Broadband Dielectric Spectroscopy ◽  
Initial Clinical Trial ◽  
Infrared Photoacoustic Spectroscopy ◽  
Increasing Demand

More than two decades have passed since the initial clinical trial of noninvasive glucose sensing using optical absorption spectroscopy. Today, noninvasive sensing technologies are expected to meet the increasing demand for high-quality diabetes management. Here, we review the latest advances in noninvasive glucose sensing research, focusing on how photonics-, acoustic- and electronics-based sensing technologies have played key roles in the development of the first noninvasive glucose sensors. We also present our recent work on multiphysics-based glucose sensing using near-infrared photoacoustic spectroscopy and broadband dielectric spectroscopy and a comparison with other competitive technologies.

Hierarchical ZnO nanorods/Ni(OH)2 nanoflakes for room-temperature, cheap fabrication of non-enzymatic glucose sensors

RSC Advances ◽  
2016 ◽  
Vol 6 (112) ◽  
pp. 111374-111379 ◽  
Author(s):  
V. Strano ◽  
S. Mirabella
Keyword(s):  
Room Temperature ◽  
Zno Nanorods ◽  
Glucose Sensing ◽  
Glucose Sensors ◽  
Hierarchical Nanostructures ◽  
Sensing Applications

Optimization of hierarchical nanostructures composed of Ni(OH)2 nanoflakes on ZnO nanorods (NRs) for inexpensive amperometric glucose sensing applications.

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