"All-in-One" Strategy Based on Organic Molecule DCN-4CQA for Effective NIR Fluorescence Imaging guided Dual Phototherapy

2021 ◽  
Author(s):  
Tianlei Zhou ◽  
Tao Jia ◽  
Lu Li ◽  
Yanjie Liu ◽  
Tiedong Sun ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Organic Molecule ◽  
Single Treatment ◽  
Therapeutic Method ◽  
Nir Fluorescence ◽  
Single Material

Combined with dual phototherapy, photodynamic therapy (PDT) and photothermal therapy (PTT), is considered as the more effective therapeutic method of cancer than single treatment. Therefore, development of single material with...

scholarly journals Near-Infrared Fluorescence Imaging and Photodynamic Therapy for Liver Tumors

2021 ◽  
Vol 11 ◽  
Author(s):  
Masaki Kaibori ◽  
Hisashi Kosaka ◽  
Kosuke Matsui ◽  
Morihiko Ishizaki ◽  
Hideyuki Matsushima ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Near Infrared ◽  
Liver Tumors ◽  
Nir Fluorescence ◽  
Recent Developments ◽  
Fluorescent Agent ◽  
Stable Particles ◽  
And Function ◽  
Cancer Tissues

Surgery with fluorescence equipment has improved to treat the malignant viscera, including hepatobiliary and pancreatic neoplasms. In both open and minimally invasive surgeries, optical imaging using near-infrared (NIR) fluorescence is used to assess anatomy and function in real time. Here, we review a variety of publications related to clinical applications of NIR fluorescence imaging in liver surgery. We have developed a novel nanoparticle (indocyanine green lactosome) that is biocompatible and can be used for imaging cancer tissues and also as a drug delivery system. To date, stable particles are formed in blood and have an ~10–20 h half-life. Particles labeled with a NIR fluorescent agent have been applied to cancer tissues by the enhanced permeability and retention effect in animals. Furthermore, this article reviews recent developments in photodynamic therapy with NIR fluorescence imaging, which may contribute and accelerate the innovative treatments for liver tumors.

Double pH-sensitive Nanotheranostics of Polypeptide Nanoparticle-Encapsulated BODIPY with Both NIR Activated Fluorescence and Enhanced Photodynamic Therapy

2021 ◽  
Author(s):  
Huiping Dang ◽  
Quan Cheng ◽  
Youliang Tian ◽  
Changchang Teng ◽  
Kai Xie ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Tumor Microenvironment ◽  
Cancer Therapy ◽  
Fluorescence Imaging ◽  
Intelligent Systems ◽  
Ph Sensitive ◽  
Nir Fluorescence

To achieve accurate fluorescence imaging-guided cancer therapy, intelligent systems with specific responsiveness to the tumor microenvironment need to be designed. Here, we have achieved both enhanced NIR fluorescence and photodynamic...

Tumor microenvironment-activated NIR-II reagents for tumor imaging and therapy

2020 ◽  
Vol 8 (22) ◽  
pp. 4738-4747 ◽  
Author(s):  
Xue Zhang ◽  
Lu An ◽  
Qiwei Tian ◽  
Jiaomin Lin ◽  
Shiping Yang
Keyword(s):  
Photodynamic Therapy ◽  
Tumor Microenvironment ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Tumor Imaging ◽  
Photoacoustic Imaging ◽  
Tumor Diagnosis ◽  
Diagnosis And Treatment ◽  
Recent Advances

This review summarizes the recent advances of tumor microenvironment-activated NIR-II agents for tumor diagnosis and treatment, including smart NIR-II fluorescence imaging, photoacoustic imaging, photothermal therapy and photodynamic therapy.

Low-work-function LaB6 for realizing photodynamic-enhanced photothermal therapy

2021 ◽  
Author(s):  
Shuanglong Tang ◽  
Weicheng Huang ◽  
Yan Gao ◽  
Na An ◽  
Yadong Wu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Work Function ◽  
Photothermal Therapy ◽  
Tumor Therapy ◽  
Single Material

Photodynamic therapy (PDT) enhanced photothermal therapy (PTT) shows great significance towards tumor therapy, especially for the single material mediated process that could greatly simplify the experimental arrangements. This study presents...

Cancer cell membrane-coated magnetic nanoparticles for MR/NIR fluorescence dual-modal imaging and photodynamic therapy

2018 ◽  
Vol 6 (7) ◽  
pp. 1834-1845 ◽  
Author(s):  
Jiong Li ◽  
Xuandong Wang ◽  
Dongye Zheng ◽  
Xinyi Lin ◽  
Zuwu Wei ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Magnetic Nanoparticles ◽  
Cell Membrane ◽  
Fluorescence Imaging ◽  
Cancer Cell ◽  
Nir Fluorescence

A photosensitizer-loaded magnetic nanobead with surface coated with a cancer cell membrane to enhance MR/NIR fluorescence imaging and PDT efficacy.

Multifunctional magnetic nanoparticles for simultaneous cancer near-infrared imaging and targeting photodynamic therapy

RSC Advances ◽  
2014 ◽  
Vol 4 (107) ◽  
pp. 62153-62159 ◽  
Author(s):  
Xueling Zhao ◽  
Zongyan Chen ◽  
Hongli Zhao ◽  
Denghao Zhang ◽  
Liang Tao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Magnetic Nanoparticles ◽  
Fluorescence Imaging ◽  
Drug Delivery System ◽  
Delivery System ◽  
Potential Application ◽  
Near Infrared ◽  
Infrared Imaging ◽  
Nir Fluorescence

In this work, a multifunctional drug delivery system was developed for potential application in NIR fluorescence imaging and targeting PDT.

scholarly journals A Review on (Hydro)Porphyrin-Loaded Polymer Micelles: Interesting and Valuable Platforms for Enhanced Cancer Nanotheranostics

Pharmaceutics ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 81
Author(s):  
Bruno Nascimento ◽  
Nelson Pereira ◽  
Artur Valente ◽  
Teresa Pinho e Melo ◽  
Marta Pineiro
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Polymeric Micelles ◽  
Therapeutic Agents ◽  
Imaging Agents ◽  
Full Potential ◽  
Polymer Micelles ◽  
Photodynamic Therapy Of Cancer ◽  
Nir Fluorescence ◽  
Theranostic Agents

Porphyrins are known therapeutic agents for photodynamic therapy of cancer and also imaging agents for NIR fluorescence imaging, MRI, or PET. A combination of interesting features makes tetrapyrrolic macrocycles suitable for use as theranostic agents whose full potential can be achieved using nanocarriers. This review provides an overview on nanotheranostic agents based on polymeric micelles and porphyrins developed so far.

scholarly journals Polymer encapsulated clinical ICG nanoparticles for enhanced photothermal therapy and NIR fluorescence imaging in cervical cancer

RSC Advances ◽  
2021 ◽  
Vol 11 (34) ◽  
pp. 20850-20858
Author(s):  
Shuang Chen ◽  
Lijun Zhu ◽  
Zhong Du ◽  
Rong Ma ◽  
Ting Yan ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Nir Fluorescence

PSMA encapsulated Clinical ICG to form ICG@PSMA nanoparticles. ICG@PSMA nanoparticles showed strong NIR fluorescence and excellent photothermal properties.

Near‐Infrared‐II Nanomaterials for Fluorescence Imaging and Photodynamic Therapy

2021 ◽  
pp. 2002177
Author(s):  
Hongxin Lin ◽  
Zexi Lin ◽  
Konghua Zheng ◽  
Chenlu Wang ◽  
Lisheng Lin ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Near Infrared

Lysosomal targeted NIR photosensitizer for photodynamic therapy and two-photon fluorescent imaging

2021 ◽  
Author(s):  
Ruiyuan Liu ◽  
Yuping Zhou ◽  
Di Zhang ◽  
Genghan He ◽  
Chuang Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Near Infrared ◽  
Fluorescent Imaging ◽  
High Fidelity ◽  
Design And Synthesis ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

Design and synthesis of near-infrared (NIR) emissive fluorophore for imaging of organelle and photodynamic therapy has received enormous attention. Hence, NIR emissive fluorophore of high-fidelity lysosome targeting, two-photon fluorescence imaging,...

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