scholarly journals Polymer encapsulated clinical ICG nanoparticles for enhanced photothermal therapy and NIR fluorescence imaging in cervical cancer

RSC Advances ◽  
2021 ◽  
Vol 11 (34) ◽  
pp. 20850-20858
Author(s):  
Shuang Chen ◽  
Lijun Zhu ◽  
Zhong Du ◽  
Rong Ma ◽  
Ting Yan ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Nir Fluorescence

PSMA encapsulated Clinical ICG to form ICG@PSMA nanoparticles. ICG@PSMA nanoparticles showed strong NIR fluorescence and excellent photothermal properties.

scholarly journals Indocyanine Green-Based Theranostic Nanoplatform for NIR Fluorescence Image-Guided Chemo/Photothermal Therapy of Cervical Cancer

2021 ◽  
Vol Volume 16 ◽  
pp. 4847-4861
Author(s):  
Rong Ma ◽  
Nuernisha Alifu ◽  
Zhong Du ◽  
Shuang Chen ◽  
Youqiang Heng ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Indocyanine Green ◽  
Photothermal Therapy ◽  
Fluorescence Image ◽  
Image Guided ◽  
Nir Fluorescence

"All-in-One" Strategy Based on Organic Molecule DCN-4CQA for Effective NIR Fluorescence Imaging guided Dual Phototherapy

2021 ◽  
Author(s):  
Tianlei Zhou ◽  
Tao Jia ◽  
Lu Li ◽  
Yanjie Liu ◽  
Tiedong Sun ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Organic Molecule ◽  
Single Treatment ◽  
Therapeutic Method ◽  
Nir Fluorescence ◽  
Single Material

Combined with dual phototherapy, photodynamic therapy (PDT) and photothermal therapy (PTT), is considered as the more effective therapeutic method of cancer than single treatment. Therefore, development of single material with...

Near-infrared fluorescence imaging with indocyanine green for quantification of changes in tissue perfusion following revascularization

Vascular ◽  
2021 ◽  
pp. 170853812110328
Author(s):  
Pim Van den Hoven ◽  
Floris S Weller ◽  
Merel Van De Bent ◽  
Lauren N Goncalves ◽  
Melissa Ruig ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Fluorescence Imaging ◽  
Fluorescence Intensity ◽  
Near Infrared ◽  
Tissue Perfusion ◽  
Control Group ◽  
Maximum Slope ◽  
Nir Fluorescence ◽  
Significant Difference ◽  
Revascularization Procedures

Objectives Current diagnostic modalities for patients with peripheral artery disease (PAD) mainly focus on the macrovascular level. For assessment of tissue perfusion, near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) seems promising. In this prospective cohort study, ICG NIR fluorescence imaging was performed pre- and post-revascularization to assess changes in foot perfusion. Methods ICG NIR fluorescence imaging was performed in 36 patients with PAD pre- and post-intervention. After intravenous bolus injection of 0.1 mg/kg ICG, the camera registered the NIR fluorescence intensity over time on the dorsum of the feet for 15 min using the Quest Spectrum Platform®. Time-intensity curves were plotted for three regions of interest (ROI): (1) the dorsum of the foot, (2) the forefoot, and (3) the hallux. Time-intensity curves were normalized for maximum fluorescence intensity. Extracted parameters were the maximum slope, area under the curve (AUC) for the ingress, and the AUC for the egress. The non-treated contralateral leg was used as a control group. Results Successful revascularization was performed in 32 patients. There was a significant increase for the maximum slope and AUC egress in all three ROIs. The most significant difference was seen for the maximum slope in ROI 3 (3.7%/s to 6.6%/s, p < 0.001). In the control group, no significant differences were seen for the maximum slope and AUC egress in all ROIs. Conclusions This study shows the potential of ICG NIR fluorescence imaging in assessing the effect of revascularization procedures on foot perfusion. Future studies should focus on the use of this technique in predicting favorable outcome of revascularization procedures.

NIR fluorescence imaging of lipid drops viscosity in liver organs of diabetic mice

2021 ◽  
Vol 187 ◽  
pp. 109120
Author(s):  
Bingli Lu ◽  
Junling Yin ◽  
Cong Liu ◽  
Weiying Lin
Keyword(s):  
Fluorescence Imaging ◽  
Diabetic Mice ◽  
Nir Fluorescence

Lanthanide-doped upconversion nanoparticles complexed with nano-oxide graphene used for upconversion fluorescence imaging and photothermal therapy

2018 ◽  
Vol 6 (4) ◽  
pp. 877-884 ◽  
Author(s):  
Po Li ◽  
Yue Yan ◽  
Binlong Chen ◽  
Pan Zhang ◽  
Siling Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Research Interest ◽  
Upconversion Nanoparticles ◽  
Multifunctional Nanoparticles ◽  
Nano Oxide

In recent years, multifunctional nanoparticles have attracted much research interest in various biomedical applications such as biosensors, diagnosis, and drug delivery systems.

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