Cancer cell membrane-coated magnetic nanoparticles for MR/NIR fluorescence dual-modal imaging and photodynamic therapy

2018 ◽  
Vol 6 (7) ◽  
pp. 1834-1845 ◽  
Author(s):  
Jiong Li ◽  
Xuandong Wang ◽  
Dongye Zheng ◽  
Xinyi Lin ◽  
Zuwu Wei ◽  
...  

A photosensitizer-loaded magnetic nanobead with surface coated with a cancer cell membrane to enhance MR/NIR fluorescence imaging and PDT efficacy.

RSC Advances ◽  
2014 ◽  
Vol 4 (107) ◽  
pp. 62153-62159 ◽  
Author(s):  
Xueling Zhao ◽  
Zongyan Chen ◽  
Hongli Zhao ◽  
Denghao Zhang ◽  
Liang Tao ◽  
...  

In this work, a multifunctional drug delivery system was developed for potential application in NIR fluorescence imaging and targeting PDT.


2021 ◽  
Vol 11 ◽  
Author(s):  
Masaki Kaibori ◽  
Hisashi Kosaka ◽  
Kosuke Matsui ◽  
Morihiko Ishizaki ◽  
Hideyuki Matsushima ◽  
...  

Surgery with fluorescence equipment has improved to treat the malignant viscera, including hepatobiliary and pancreatic neoplasms. In both open and minimally invasive surgeries, optical imaging using near-infrared (NIR) fluorescence is used to assess anatomy and function in real time. Here, we review a variety of publications related to clinical applications of NIR fluorescence imaging in liver surgery. We have developed a novel nanoparticle (indocyanine green lactosome) that is biocompatible and can be used for imaging cancer tissues and also as a drug delivery system. To date, stable particles are formed in blood and have an ~10–20 h half-life. Particles labeled with a NIR fluorescent agent have been applied to cancer tissues by the enhanced permeability and retention effect in animals. Furthermore, this article reviews recent developments in photodynamic therapy with NIR fluorescence imaging, which may contribute and accelerate the innovative treatments for liver tumors.


Author(s):  
Huiping Dang ◽  
Quan Cheng ◽  
Youliang Tian ◽  
Changchang Teng ◽  
Kai Xie ◽  
...  

To achieve accurate fluorescence imaging-guided cancer therapy, intelligent systems with specific responsiveness to the tumor microenvironment need to be designed. Here, we have achieved both enhanced NIR fluorescence and photodynamic...


The Analyst ◽  
2021 ◽  
Author(s):  
Pengxiang Lin ◽  
Liangliang Zhang ◽  
Dongxia Chen ◽  
Jiayao Xu ◽  
Yulong Bai ◽  
...  

A DNA-functionalized biomass nanoprobe was developed for the targeted photodynamic therapy of tumor and ratiometric fluorescence imaging-based visual cancer cell identification/antitumor drug screening.


Biomaterials ◽  
2017 ◽  
Vol 142 ◽  
pp. 149-161 ◽  
Author(s):  
Shi-Ying Li ◽  
Hong Cheng ◽  
Wen-Xiu Qiu ◽  
Lu Zhang ◽  
Shuang-Shuang Wan ◽  
...  

Nanoscale ◽  
2018 ◽  
Vol 10 (38) ◽  
pp. 18124-18130 ◽  
Author(s):  
Mingyue Xue ◽  
Jingjin Zhao ◽  
Zhihua Zhan ◽  
Shulin Zhao ◽  
Chuanqing Lan ◽  
...  

Dual functionalized natural biomass carbon dots from lychee exocarp were fabricated for cancer cell targetable near-infrared fluorescence imaging and photodynamic therapy.


2020 ◽  
Vol 11 (37) ◽  
pp. 10279-10286 ◽  
Author(s):  
Yingcui Bu ◽  
Tianren Xu ◽  
Xiaojiao Zhu ◽  
Jie Zhang ◽  
Lianke Wang ◽  
...  

A NIR-I light initiated theranostic system based on photosensitizer EBD-1 with cancer cell membrane targeting ability, which can self-report cell viability.


ACS Nano ◽  
2017 ◽  
Vol 11 (7) ◽  
pp. 7006-7018 ◽  
Author(s):  
Shi-Ying Li ◽  
Hong Cheng ◽  
Bo-Ru Xie ◽  
Wen-Xiu Qiu ◽  
Jing-Yue Zeng ◽  
...  

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