scholarly journals PLGA-coated methylene blue nanoparticles for photoacoustic imaging and photodynamic/photothermal cascaded precisely synergistic therapy of tumor

RSC Advances ◽  
2022 ◽  
Vol 12 (3) ◽  
pp. 1543-1549
Author(s):  
Xiaomu Xu ◽  
Haiyan Wu ◽  
Yue Yang ◽  
Bo Liu ◽  
Jijing Tian ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Photodynamic Therapy ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Treatment Strategies ◽  
Anticancer Efficacy

Photodynamic therapy (PDT) and photothermal therapy (PTT) are synergetic treatment strategies in antitumor treatment to achieve the best anticancer efficacy.

Tumor microenvironment-activated NIR-II reagents for tumor imaging and therapy

2020 ◽  
Vol 8 (22) ◽  
pp. 4738-4747 ◽  
Author(s):  
Xue Zhang ◽  
Lu An ◽  
Qiwei Tian ◽  
Jiaomin Lin ◽  
Shiping Yang
Keyword(s):  
Photodynamic Therapy ◽  
Tumor Microenvironment ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Tumor Imaging ◽  
Photoacoustic Imaging ◽  
Tumor Diagnosis ◽  
Diagnosis And Treatment ◽  
Recent Advances

This review summarizes the recent advances of tumor microenvironment-activated NIR-II agents for tumor diagnosis and treatment, including smart NIR-II fluorescence imaging, photoacoustic imaging, photothermal therapy and photodynamic therapy.

scholarly journals Antimicrobial Capacity and Surface Alterations Using Photodynamic Therapy and Light Activated Disinfection on Polymer-Infiltrated Ceramic Material Contaminated with Periodontal Bacteria

2020 ◽  
Vol 13 (11) ◽  
pp. 350
Author(s):  
Elzahraa Eldwakhly ◽  
Selma Saadaldin ◽  
Alhanoof Aldegheishem ◽  
Marwa Salah Mostafa ◽  
Mai Soliman
Keyword(s):  
Methylene Blue ◽  
Photodynamic Therapy ◽  
Diode Laser ◽  
Bacterial Species ◽  
Treatment Strategies ◽  
Visual Assessment ◽  
Dead Cell ◽  
Contact Mode ◽  
Antimicrobial Efficiency ◽  
Periodontal Bacteria

This study determined the antimicrobial efficiency of light-activated disinfection (LAD) and photodynamic therapy (PDT) on polymer-infiltrated ceramic network (PICN) material contaminated with three periodontal bacteria and explored if PDT and LAD cause PICN surface alterations. Sixty PICN discs were contaminated with Tannerella forsythia, Porphyromonas gingivalis, and Treponema denticola and randomly divided into five groups (n = 12 samples/each) according to the treatment groups: Group PDT—PDT (630 ± 10 nm diode laser) with methylene blue; Group DL—808 nm diode laser in contact mode without photosensitizer; Group MB–methylene blue without light application; Group CHX—0.12% chlorhexidine digluconate solution and; Group NT—no treatment. Each disc was then placed in tubes containing phosphate buffered saline (PBS) and vortexed for 30 s to remove the remaining bacteria from the discs. A total of 10× serial dilutions were performed followed by plating of 30 μL of suspension on Brucella agar plates. The colony forming units (CFU) were calculated after 72 h. PICN discs with the attached biofilms were used for confocal microscopy investigation for live/dead bacterial viability. A random single sample from each group was selected to study the bacterial adherence and topographical alterations on PICN discs under scanning electron microscope (SEM). The PDT group showed higher reduction for each bacterial species and total counts of bacteria assessed followed by the DL group (p < 0.05). When compared with MB group, the two laser groups were significantly superior (p < 0.05). The MB group did not show significant differences for any bacteria when compared to NT. The bacteria with the CHX group and DL groups appeared dead with few areas of surviving green stained bacteria. The PDT group showed the highest dead cell count (p < 0.05). PDT and DL groups indicate no significant changes on the surface compared to the sterile PICN discs on visual assessment. Photodynamic therapy produced superior periodontal bacteria reduction over the surface of PICN surface. PDT group showed higher reduction for each bacterial species and total counts of bacteria assessed followed by the DL group. Both PDT and DL treatment strategies are effective without producing surface alterations on PICN.

Biocompatible nitrogen-doped carbon dots: synthesis, characterization, and application

2020 ◽  
Vol 8 (39) ◽  
pp. 8935-8951
Author(s):  
Yoonsang Park ◽  
Yujin Kim ◽  
Heemin Chang ◽  
Sungyeon Won ◽  
Hyemin Kim ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Carbon Dots ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Photoacoustic Imaging ◽  
Carbon Nanomaterial ◽  
Nitrogen Doped ◽  
Doped Carbon Dots ◽  
Nitrogen Doped Carbon

Nitrogen-doped carbon dots have emerged as a biocompatible functional carbon nanomaterial for a variety of biomedical applications such as optical imaging, photoacoustic imaging, drug delivery, photothermal therapy, and photodynamic therapy.

Ce6-Conjugated and polydopamine-coated gold nanostars with enhanced photoacoustic imaging and photothermal/photodynamic therapy to inhibit lung metastasis of breast cancer

Nanoscale ◽  
2020 ◽  
Vol 12 (43) ◽  
pp. 22173-22184
Author(s):  
Ziwei Li ◽  
Fan Yang ◽  
Di Wu ◽  
Yanhong Liu ◽  
Yang Gao ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Photodynamic Therapy ◽  
Lung Metastasis ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Chlorin E6 ◽  
Gold Nanostars ◽  
Gold Nanostar

Chlorin e6 (Ce6)-conjugated and polydopamine (PDA)-coated gold nanostar (AuNS) nanocomposites (AuNSs@PDA-Ce6) with enhanced photoacoustic (PA) imaging, photothermal therapy (PTT) and photodynamic therapy (PDT) to inhibit lung metastasis of breast cancer.

scholarly journals Artificial Cell-Mediated Photodynamic Therapy Enhanced Anticancer Efficacy through Combination of Tumor Disruption and Immune Response Stimulation

ACS Omega ◽  
2019 ◽  
Vol 4 (7) ◽  
pp. 12727-12735 ◽  
Author(s):  
Jiang Ni ◽  
Ying Sun ◽  
Jinfang Song ◽  
Yiqing Zhao ◽  
Qiufang Gao ◽  
...  
Keyword(s):  
Immune Response ◽  
Photodynamic Therapy ◽  
Anticancer Efficacy ◽  
Artificial Cell

Pyrazino[2,3-g]quinoxaline-Based Nanoparticles as Near-Infrared Phototheranostic Agents for Efficient Photoacoustic-Imaging-Guided Photothermal Therapy

2021 ◽  
Vol 4 (2) ◽  
pp. 2019-2029
Author(s):  
Li-Peng Zhang ◽  
Lin Kang ◽  
Xianqiang Li ◽  
Shiyang Liu ◽  
Tianlong Liu ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Near Infrared ◽  
Photoacoustic Imaging
Sign in / Sign up

Export Citation Format

Share Document