scholarly journals Optimization of synthetic parameters of high-purity trifunctional mercaptoesters and their curing behavior for the thiol–epoxy click reaction

RSC Advances ◽  
2021 ◽  
Vol 11 (54) ◽  
pp. 34263-34268
Author(s):  
Seung-Mo Hong ◽  
Oh Young Kim ◽  
Seok-Ho Hwang
Keyword(s):  
High Purity ◽  
Click Reaction ◽  
Esterification Reaction ◽  
Synthetic Route ◽  
Curing Behavior ◽  
Direct Esterification ◽  
Mercaptopropionic Acid

The direct esterification reaction between 3-mercaptopropionic acid and trimethylolpropane was conducted in the presence of various catalyst concentrations to find a synthetic route for high-purity trimethylolpropane-tris(3-mercaptopropionate).

Multiply functionalized dendrimers: protective-group-free synthesis through sequential thiol-epoxy ‘click’ chemistry and esterification reaction

RSC Advances ◽  
2015 ◽  
Vol 5 (55) ◽  
pp. 43961-43964 ◽  
Author(s):  
Ikhlas Gadwal ◽  
Anzar Khan
Keyword(s):  
Click Chemistry ◽  
Esterification Reaction ◽  
Synthetic Route ◽  
Protective Group

A protective-group-free synthetic route to multiply functionalized dendrimers is presented.

scholarly journals Design and simulation of high purity biodiesel reactive distillation process

2019 ◽  
Vol 21 (3) ◽  
pp. 1-7 ◽  
Author(s):  
Syed Sadiq Ali ◽  
Mohammad Asif ◽  
Avijit Basu
Keyword(s):  
High Purity ◽  
Fossil Fuels ◽  
Distillation Column ◽  
Reactive Distillation ◽  
Aspen Plus ◽  
Esterification Reaction ◽  
Distillation Process ◽  
Water Composition ◽  
Product Stream ◽  
Process Simulator

Abstract Biodiesel is a promising energy substitute of fossil fuels since it is produced from renewable and biodegradable sources. In the present work, reactive distillation (RD) process is designed and simulated using Aspen Plus process simulator to produce biodiesel of high purity through esterification reaction. The simultaneous reaction and separation in same unit enhances the biodiesel yield and composition in RD process. Two flowsheets are proposed in present work. In the first flowsheet, the unreacted methanol is recycled back to reactive distillation column. Biodiesel with 99.5 mol% purity is obtained in product stream while the byproduct stream comprises 95.2 mol% water, which has to be treated further. In the second flowsheet, a part of methanol recycle is split and purged. In this case, the biodiesel composition in product stream is 99.7 mol% whereas water composition is 99.9 mol% in byproduct stream, which can be reused for other process without treatment.

scholarly journals Synthesis of Novel N-Heterocyclic Compounds Containing 1,2,3-Triazole Ring System via Domino, “Click” and RDA Reactions

Molecules ◽  
2019 ◽  
Vol 24 (4) ◽  
pp. 772 ◽  
Author(s):  
Márta Palkó ◽  
Mohamed El Haimer ◽  
Zsanett Kormányos ◽  
Ferenc Fülöp
Keyword(s):  
Heterocyclic Compounds ◽  
Click Reaction ◽  
Triazole Ring ◽  
Heterocyclic Ring ◽  
Ring System ◽  
Diels Alder ◽  
Ring Closure ◽  
Synthetic Route ◽  
13C Nuclear Magnetic Resonance ◽  
Nmr Methods

An uncomplicated, high-yielding synthetic route has been developed to constitute complicated heterocycles, applying domino, click and retro-Diels–Alder (RDA) reaction sequences. Starting from 2-aminocarboxamides, a new set of isoindolo[2,1-a]quinazolinones was synthesized with domino ring closure. A click reaction was performed to create the 1,2,3-triazole heterocyclic ring, followed by an RDA reaction resulting in dihydropyrimido[2,1-a]isoindole-2,6-diones. The absolute configuration, concluded by the norbornene structure that served as a chiral source, remained constant throughout the transformations. The structure of the synthesized compounds was examined by 1H and 13C Nuclear Magnetic Resonance (NMR) methods.

A new procedure for the synthesis of 2-[(4-dodecyloxyphenyl)sulfonyl]butanoic acid

2015 ◽  
Vol 69 (9) ◽  
Author(s):  
Yun-Long Shi ◽  
Ling Wang ◽  
Chao Qian ◽  
Ming Tao ◽  
Zu-Tai Liao ◽  
...  
Keyword(s):  
High Purity ◽  
Cost Effective ◽  
Target Product ◽  
Synthetic Route ◽  
Butanoic Acid ◽  
Nucleophilic Reaction ◽  
Synthetic Strategy ◽  
Scalable Synthesis ◽  
Optimized Conditions ◽  
Important Objective

AbstractA new, practical and cost-effective route for scalable synthesis of 2-[(4-dodecyloxyphenyl)sulfonyl] butanoic acid, a key intermediate of a new cyan dye-forming coupler containing a sulfone group, was developed by adopting phenol as the starting material. The synthesis was accomplished in five steps with etherification, chlorosulfonation, reduction, nucleophilic reaction by C-S coupling and hydrolyzation. An important objective of the new synthetic route was the synthesis of 2-[4- (dodecyloxyphenyl)sulfonyl]butanoate. Overall yield obtained at optimized conditions increased to 66 %. The synthetic strategy was proven to be a process enabling rapid delivery of the target product with high purity.

scholarly journals An Improved, Highly Efficient Method for the Synthesis of Bisphenols

2011 ◽  
Vol 8 (4) ◽  
pp. 2016-2019 ◽  
Author(s):  
L. S. Patil ◽  
V. S. Suryawanshi ◽  
O. B. Pawar ◽  
N. D. Shinde
Keyword(s):  
Efficient Method ◽  
High Purity ◽  
Cetyltrimethylammonium Chloride ◽  
Efficient Synthesis ◽  
Cyclic Ketones ◽  
Substituted Phenols ◽  
Mercaptopropionic Acid ◽  
Highly Efficient

An efficient synthesis of bisphenols is described by condensation of substituted phenols with corresponding cyclic ketones in presence of cetyltrimethylammonium chloride and 3-mercaptopropionic acid as a catalyst in extremely high purity and yields.

scholarly journals Synthesis of Carvone-Derived 1,2,3-Triazoles Study of Their Antioxidant Properties and Interaction with Bovine Serum Albumin

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2991 ◽  
Author(s):  
Armen Galstyan ◽  
Armen Martiryan ◽  
Karine Grigoryan ◽  
Armine Ghazaryan ◽  
Melanya Samvelyan ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Serum Albumin ◽  
Hydrophobic Interactions ◽  
Click Reaction ◽  
Antioxidant Properties ◽  
Synthetic Route ◽  
Efficient Synthesis ◽  
Solubility In Water ◽  
Reversible Binding ◽  
High Antioxidant Activity

Natural L-carvone was utilized as a starting material for an efficient synthesis of some terpenyl-derived 1,2,3-triazoles. Chlorination of carvone, followed by nucleophilic substitution with sodium azide resulted in the preparation of 10-azidocarvone. Subsequent CuAAC click reaction with propargylated derivatives provided an efficient synthetic route to a set of terpenyl-derived conjugates with increased solubility in water. All investigated compounds exhibit high antioxidant activity, which is comparable with that of vitamin C. It was also found that serum albumin and the terpenyl-1,2,3-triazoles hybrids spontaneously undergo reversible binding driven by hydrophobic interactions, suggesting that serum albumin can transport the target triazoles.

Sign in / Sign up

Export Citation Format

Share Document