Multiply functionalized dendrimers: protective-group-free synthesis through sequential thiol-epoxy ‘click’ chemistry and esterification reaction

RSC Advances ◽  
2015 ◽  
Vol 5 (55) ◽  
pp. 43961-43964 ◽  
Author(s):  
Ikhlas Gadwal ◽  
Anzar Khan
Keyword(s):  
Click Chemistry ◽  
Esterification Reaction ◽  
Synthetic Route ◽  
Protective Group

A protective-group-free synthetic route to multiply functionalized dendrimers is presented.

A synthetic route to 2,6-bis-triazolyl purine deoxynucleosides via click chemistry

2014 ◽  
Author(s):  
Dace Cīrule ◽  
Kristers Ozols ◽  
Irina Novosjolova ◽  
Māris Turks ◽  
Ērika Bizdēna
Keyword(s):  
Click Chemistry ◽  
Synthetic Route

Precise synthesis of thermoresponsive polyvinylphosphonate-biomolecule conjugatesviathiol–ene click chemistry

2018 ◽  
Vol 9 (3) ◽  
pp. 284-290 ◽  
Author(s):  
Christina Schwarzenböck ◽  
Andreas Schaffer ◽  
Philipp Pahl ◽  
Peter J. Nelson ◽  
Ralf Huss ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Synthetic Route

Herein we present the first smart polyvinylphosphonate-bioconjugates obtainedviaan efficient modular synthetic route.

Click Chemistry on a Ruthenium Polypyridine Complex. An Efficient and Versatile Synthetic Route for the Synthesis of Photoactive Modular Assemblies

2012 ◽  
Vol 51 (11) ◽  
pp. 5985-5987 ◽  
Author(s):  
Aurélie Baron ◽  
Christian Herrero ◽  
Annamaria Quaranta ◽  
Marie-France Charlot ◽  
Winfried Leibl ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Synthetic Route ◽  
Ruthenium Polypyridine

Thiol–ene click chemistry: a modular approach to solid-state triplet–triplet annihilation upconversion

2018 ◽  
Vol 6 (15) ◽  
pp. 3876-3881 ◽  
Author(s):  
Abagail K. Williams ◽  
Brad J. Davis ◽  
Erin R. Crater ◽  
Joseph R. Lott ◽  
Yoan C. Simon ◽  
...  
Keyword(s):  
Solid State ◽  
Click Chemistry ◽  
Modular Approach ◽  
Synthetic Route ◽  
On Demand ◽  
Host Materials ◽  
Triplet Triplet Annihilation

Thiol–ene click chemistry can be used as a facile cure-on-demand synthetic route to access robust host materials for solid-state upconversion.

scholarly journals Optimization of synthetic parameters of high-purity trifunctional mercaptoesters and their curing behavior for the thiol–epoxy click reaction

RSC Advances ◽  
2021 ◽  
Vol 11 (54) ◽  
pp. 34263-34268
Author(s):  
Seung-Mo Hong ◽  
Oh Young Kim ◽  
Seok-Ho Hwang
Keyword(s):  
High Purity ◽  
Click Reaction ◽  
Esterification Reaction ◽  
Synthetic Route ◽  
Curing Behavior ◽  
Direct Esterification ◽  
Mercaptopropionic Acid

The direct esterification reaction between 3-mercaptopropionic acid and trimethylolpropane was conducted in the presence of various catalyst concentrations to find a synthetic route for high-purity trimethylolpropane-tris(3-mercaptopropionate).

PEMBUATAN SURFAKTAN DARI ASAM OLEAT

2019 ◽  
Vol 1 (3) ◽  
pp. 68
Author(s):  
Puguh Setyopratomo ◽  
Edy Purwanto ◽  
H. Yefrico ◽  
H. Yefrico
Keyword(s):  
Oleic Acid ◽  
Optimum Condition ◽  
Reaction Temperature ◽  
Catalyst Concentration ◽  
Acid Number ◽  
Esterification Reaction ◽  
Number Density ◽  
Sample Analysis ◽  
Reaction Conversion ◽  
Glycerol Mono

The synthesis of glycerol mono oleic from oleic acid and glycerol is classified as an esterification reaction. This research is aimed to study the influent of reaction temperature and catalyst concentration on reaction conversion. During the experiment the temperature of reaction mixture was varied as 110 oC, 130 oC, and 150 oC, while the catalyst concentration of 1%, 3 %, and 5% was used. The batch experiment was conducted in a glass reactor equipped with termometer, agitator, and reflux condensor. The oleic acid – glycerol mol ratio of 1 : 2 was used as a mixture feed. To maintain the reaction temperature at certain level, the oil bath was used. After the temperature of reaction mixture was reached the expected value, then H2SO4 catalyst was added to the reactor.  To measure the extent of the reaction, every 30 minutes the sample was drawn out from the reactor vessel. The sample analysis include acid number, density, and viscosity measurement. From this research the optimum condition which is the temperature of reaction of 150 oC and 1% catalyst concentration was obtained. At this optimum condition the convertion reach 86% and the analysis of other physical properties of the product show the acid number of 24.12, the density of 0.922 g/cc, and the viscosity of 118.4 cp.

A General Convergent Strategy for the Synthesis of Tetrasubstituted Furan Fatty Acids (FuFAs)

2019 ◽  
Author(s):  
Yamin Wang ◽  
Gareth Pritchard ◽  
Marc Kimber
Keyword(s):  
Fatty Acids ◽  
Spectral Data ◽  
Synthetic Route ◽  
Furan Fatty Acids

Synthetic route for the synthesis of tetrasubstituted furan fatty acids; including experimental details, characterisation, and spectral data of all intermediates.

Click Chemistry Expedited Radiosynthesis: Sulfur [18F]fluoride Exchange of Aryl Fluorosulfates

2019 ◽  
Author(s):  
Qinheng Zheng ◽  
Hongtao Xu ◽  
Hua Wang ◽  
Wen-Ge Han Du ◽  
Nan Wang ◽  
...  
Keyword(s):  
Click Chemistry ◽  
High Performance ◽  
Isotopic Exchange ◽  
Tumor Imaging ◽  
Radiochemical Yield ◽  
Exchange Method ◽  
Molar Activity ◽  
Positron Emission ◽  
Sulfur Fluoride

The lack of simple, efficient [<sup>18</sup>F]fluorination processes and new target-specific organofluorine probes remains the major challenge of fluorine-18-based positron emission tomography (PET). We report here a fast isotopic exchange method for the radiosynthesis of aryl [<sup>18</sup>F]fluorosulfate based PET agents enabled by the emerging sulfur fluoride exchange (SuFEx) click chemistry. The method has been applied to the fully-automated <sup>18</sup>F-radiolabeling of twenty-five structurally diverse aryl fluorosulfates with excellent radiochemical yield (83–100%) and high molar activity (up to 281 GBq µmol<sup>–1</sup>) at room temperature in 30 seconds. The purification of radiotracers requires no time-consuming high-performance liquid chromatography (HPLC), but rather a simple cartridge filtration. The utility of aryl [<sup>18</sup>F]fluorosulfate is demonstrated by the <i>in vivo</i> tumor imaging by targeting poly(ADP-ribose) polymerase 1 (PARP1).

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