scholarly journals The phytochemistry, pharmacology and traditional medicinal use of Glechomae Herba – a systematic review

RSC Advances ◽  
2021 ◽  
Vol 11 (31) ◽  
pp. 19221-19237
Author(s):  
Liu Yang ◽  
Jiaxu Zhang ◽  
Senwang Zheng ◽  
Ajiao Hou ◽  
Song Wang ◽  
...  

Glechomae Herba is a Chinese herb, which has been used in China for thousands of years, mainly for the treatment of nephrolithiasis.

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Rong-liang Dun ◽  
Min Yao ◽  
Long Yang ◽  
Xue-jun Cui ◽  
Jian-min Mao ◽  
...  

Objective. The objective of this study was to conduct a systematic review to assess the effectiveness and safety of traditional Chinese herb combined with surgery for male varicocele infertility compared to surgery.Methods. Randomized controlled trials (RCTs) data of traditional Chinese herbs combined with surgery for male varicocele fertility versus surgery were collected by searching the Cochrane Library, Embase, PubMed, and Chinese databases. The risk of bias was assessed using Cochrane Handbook. Study outcomes were presented as risk ratios (RRs) for dichotomous data.Results. Seventeen of 72 potentially relevant trials met the inclusion criteria. The methodological qualities of the RCTs were low. Compared with the surgery group, the traditional Chinese herb combined with surgery group had superiority in pregnancy rate at 3-month (RR=1.76, andP=0.008), 6-month (RR=1.58, andP=0.0005), and 2-year (RR=1.58, andP=0.0005) follow-ups. No RCT was found to describe the side effects.Conclusion. On considering the low methodological quality of RCTs, there was no enough evidence on traditional Chinese herb with surgery for male varicocele infertility, and more high-quality RCTs of large sample sizes are required.


2020 ◽  
Vol 14 (2) ◽  
pp. 62-72 ◽  
Author(s):  
Norma Fernandes Lima Cícera ◽  
Ferreira de Lima Luciene ◽  
Bezerra Correia Denise ◽  
Tavares de Sousa Machado Sara ◽  
Pereira de Sousa Jéssica ◽  
...  

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 948-948
Author(s):  
Tristesse Burton ◽  
James Alexander ◽  
Petar Planinic ◽  
Arpita Basu

Abstract Objectives Gestational diabetes mellitus (GDM) is one of the most common health complications during pregnancy. Medical nutrition therapy is the mainstay of treatment for GDM, however, there is no current consensus on the optimal dietary approaches for prevention and management of hyperglycemia during pregnancy. Our objective is to assess the relationship of plant-based diets, foods, and dietary supplements with GDM and maternal glycemic biomarkers in observational and clinical studies. Methods A systematic review was performed using PubMed to identify original articles from 1999–2019 following the PRISMA checklist statement. Articles were excluded if they were review articles, conference abstracts, not in English or did not meet the pre-defined PICOS (Population, Intervention/exposure, Comparison, Outcome, Study design) criteria. Articles were screened for relevance, extracted and summarized, and assessed for risk of bias and quality. Results A total of 431 articles were screened, 33 observational studies (prospective cohort: n = 26, case-control: n = 3, cross-sectional: n = 4) involving 147,576 women and 11 randomized clinical trials involving 3940 women were included. Among the observational studies, Mediterranean diet (MedDiet), fiber, and vegetable rich diets were associated with a significant decrease in GDM risk. Among the clinical trials, Dietary Approaches to Stop Hypertension (DASH) diet, MedDiet, soy, phytosterol spread, evening primrose, chili powder and a traditional Chinese herb, Artemisia scoparia Waldst. & Kit. (Asteraceae) (n = 1) exhibited improved maternal hyperglycemia, insulin resistance or sensitivity, and hypoadiponectinemia. Conclusions These findings suggest that plant-based diets may be effective in preventing and managing hyperglycemia during pregnancy. Particularly, adherence to a MedDiet may improve maternal glycemic biomarker and decrease risk of GDM. Funding Sources UNLV Faculty research start up award.


Author(s):  
Abha Shukla ◽  
Amanpreet Kaur

 The plants of the genus Ehretia composed of about 150 species mainly distributed in tropical Asia, Africa, Australia, and North America. They have been used as traditional and folk medicines to treat various ailments in Japan, India, and China for a long time. Previous phytochemical screenings demonstrated that the Ehretia plants mainly contain fatty acids, phenolic acids, flavonoids, cyanogenetic glycosides, and benzoquinones and other constituents from different chemical classes. The pharmacological studies confirmed that the crude extracts or individual compounds from the genus showed antioxidant, anti-inflammatory, antibacterial, antiarthritic, antitubercular, and antiallergic activities, as well as anti-snake venom property. In this review, we presented a summary of the secondary metabolites isolated from different species of Ehretia based on the published literatures up to March 2017. In addition to the traditional medicinal use of Ehretia plants, we focused on the known biological activities of the plants and discussed them in detail here.


Medicina ◽  
2020 ◽  
Vol 56 (6) ◽  
pp. 309 ◽  
Author(s):  
Lourdes Poyatos ◽  
Ana Pilar Pérez-Acevedo ◽  
Esther Papaseit ◽  
Clara Pérez-Mañá ◽  
Soraya Martin ◽  
...  

Background and objective: Changes in cannabis legalization regimes in several countries have influenced the diversification of cannabis use. There is an ever-increasing number of cannabis forms available, which are gaining popularity for both recreational and therapeutic use. From a therapeutic perspective, oral cannabis containing Δ-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) is a promising route of administration but there is still little information about its pharmacokinetics (PK) effects in humans. The purpose of this systematic review is to provide a general overview of the available PK data on cannabis and THC after oral administration. Materials and Methods: A search of the published literature was conducted using the PubMed database to collect available articles describing the PK data of THC after oral administration in humans. Results: The literature search yielded 363 results, 26 of which met our inclusion criteria. The PK of oral THC has been studied using capsules (including oil content), tablets, baked goods (brownies and cookies), and oil and tea (decoctions). Capsules and tablets, which mainly correspond to pharmaceutical forms, were found to be the oral formulations most commonly studied. Overall, the results reflect the high variability in the THC absorption of oral formulations, with delayed peak plasma concentrations compared to other routes of administration. Conclusions: Oral THC has a highly variable PK profile that differs between formulations, with seemingly higher variability in baked goods and oil forms. Overall, there is limited information available in this field. Therefore, further investigations are required to unravel the unpredictability of oral THC administration to increase the effectiveness and safety of oral formulations in medicinal use.


2010 ◽  
Vol 25 (5) ◽  
pp. 787-788 ◽  
Author(s):  
Stijn Van de Velde ◽  
Emmy De Buck ◽  
Tessa Dieltjens ◽  
Bert Aertgeerts

2021 ◽  
Vol 6 (3) ◽  
pp. 018-021
Author(s):  
Corrêa Leonardo Tibiriçá ◽  
Peña Muñoz Juliana Weckx ◽  
Pacca Faria Beatriz do Prado ◽  
Santana Jeferson ◽  
Rocha Leandro Yanase ◽  
...  

Marijuana is considered illicit in much of the world, and is classified as a drug for recreational use, in recent decades the medicinal use of Cannabis sativa L. has grown and diversified, being considered the only therapeutic alternative in the control of serious and incurable diseases such as syndrome of Dravet. The world panorama has shown a more liberal position, since in several countries such as the United States of America, Holland, Australia, Italy, and more recently in Canada, the use of medications, or even the recreational use of this plant, have been regulated. In this context, the investigation of the modifying effects on physical activity of empirically used cannabinoids is fundamental nowadays, mainly due to the regulatory recognition of Cannabis sativa L. as a medicinal plant in a large part of the world. Therefore, the objective of this review was to verify the evidence related to the effect of cannabis on physical performance and to identify and highlight the challenges in the interpretation of information regarding the performance of practitioners of physical activity, as well as athletes, presenting new trends in this area of research to be addressed. To carry out the systematic review, a bibliographic survey of case reports was obtained through Pubmed, Science Direct and Google Academic databases. The following keywords were used to perform the research: cannabis, performance, pain, competition. The following filters were used as inclusion criteria a languages used english; species: humans; types of articles: original articles and reviews and period of publication of articles: 1981 to 2021.


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