The facile and efficient synthesis of novel monocyclic cis-β-lactams conjugates having 1-methyl-1H-imidazole-2-thio nucleus

2021 ◽  
Author(s):  
Vedeshwar Narayan Singh ◽  
Sitaram Sharma

In this paper, the facile and efficient synthesis of novel monocyclic cis-β-lactam conjugates having 1-methyl-1H-imidazole-2-thiol nucleus has been developed through ketene-imine [2+2] cyclo-addition reaction of acyl chloride and different Schiff’s...

2021 ◽  
pp. 130140
Author(s):  
Liangliang Xie ◽  
Tao Zhang ◽  
Emad Karrar ◽  
Dan Xie ◽  
Liyou Zheng ◽  
...  

Author(s):  
Yong Wang ◽  
Yu-Jiao Wang ◽  
Xian-Cheng Liang ◽  
Mei-Hua Shen ◽  
Hua-Dong Xu ◽  
...  

The addition reaction of thiol to vinyl azide has been extensively studied. Variously substituted aryl thiols are all viable for this coupling process. The scope of the other partner is...


Synlett ◽  
2017 ◽  
Vol 28 (10) ◽  
pp. 1183-1186 ◽  
Author(s):  
Nobuhiro Obara ◽  
Takeshi Watanabe ◽  
Tomohiro Asakawa ◽  
Toshiyuki Kan ◽  
Takao Tanaka

A convenient method for synthesizing 3-amino-1,5-benzodiazepine-2-one via the Michael addition reaction of o-phenylenediamine with dehydroalanine ester derivatives, followed by cyclization, was developed. This simple method was used to obtain a variety of N-substituted 3-amino-1,5-benzodiazepine-2-ones in one pot with good yields.


RSC Advances ◽  
2012 ◽  
Vol 2 (30) ◽  
pp. 11215 ◽  
Author(s):  
Min Zhang ◽  
Erhong Hao ◽  
Yajun Xu ◽  
Shengzhou Zhang ◽  
Hongnian Zhu ◽  
...  

2018 ◽  
Vol 8 (4) ◽  
pp. 671-676
Author(s):  
Shrikant Anpat ◽  
Vijay V. Dabholkar ◽  
Sandip Gulve ◽  
Karthik Krishnan

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