Synthesis of Acridines through Alkyne Addition to Diarylamines

A new synthesis of substituted acridines is achieved by palladium-catalyzed addition of terminal acetylenes between the aryl rings of bis(2-bromophenyl)amine. By including a diamine base and elevating the temperature, the reaction pathway favors the formation of acridine over a double Sonogashira reaction to form bis(tolan)amine. This method is demonstrated with several aryl-alkynes and alkyl-alkynes.

Selective formation of heterocyclic trans-cycloalkenes by alkyne addition to a biphenylene-based phosphane/borane frustrated Lewis pair

A biphenylene based P/B FLP reacts with 1-alkynes through trans-1,2-addition to give heterocyclic E-cycloalkene products.

Additive-modulated switchable reaction pathway in the addition of alkynes with organosilanes catalyzed by supported Pd nanoparticles: hydrosilylation versus semihydrogenation

A supported Pd nanoparticles on N,O-doped hierarchical porous carbon enabled additive-modulated reaction pathway for alkyne addition with organosilanes between hydrosilylation and semihydrogenation.