Nanoemulsion Delivery Systems for Enhanced Efficacy of Antimicrobials and Essential Oils

2022 ◽  
Author(s):  
Celine Renea Garcia ◽  
Muhammad H. Malik ◽  
Sujit Biswas ◽  
Vincent H. Tam ◽  
Kendra P Rumbaugh ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Antimicrobial Resistance ◽  
Infectious Diseases ◽  
Essential Oils ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Optimal Drug

The ever-growing threat of new and existing infectious diseases in combination with antimicrobial resistance requires the need for innovative and effective forms of drug delivery. Optimal drug delivery systems for...

Drug delivery systems designed to overcome antimicrobial resistance

2019 ◽  
Vol 39 (6) ◽  
pp. 2343-2396 ◽  
Author(s):  
Thanh‐Nhat Pham ◽  
Pauline Loupias ◽  
Alexandra Dassonville‐Klimpt ◽  
Pascal Sonnet
Keyword(s):  
Drug Delivery ◽  
Antimicrobial Resistance ◽  
Drug Delivery Systems ◽  
Delivery Systems

scholarly journals Recent trends on hydrogel based drug delivery systems for infectious diseases

2016 ◽  
Vol 4 (11) ◽  
pp. 1535-1553 ◽  
Author(s):  
Arti Vashist ◽  
Ajeet Kaushik ◽  
Atul Vashist ◽  
Rahul Dev Jayant ◽  
Asahi Tomitaka ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Infectious Diseases ◽  
Targeted Drug Delivery ◽  
Drug Delivery Systems ◽  
Therapeutic Agents ◽  
Delivery Systems ◽  
Recent Trends ◽  
Targeted Drug ◽  
Targeted Drug Delivery Systems

Hydrogel based drug delivery systems owe excellent potential as targeted drug delivery systems for the delivery of therapeutic agents and diagnostics for major infectious diseases.

scholarly journals Drug Delivery Systems for Infectious Diseases

Drug Delivery ◽  
2017 ◽  
pp. 349-372
Author(s):  
Maximiliano L. Cacicedo ◽  
Germán A. Islan ◽  
Pablo Gurman ◽  
Guillermo R. Castro
Keyword(s):  
Drug Delivery ◽  
Infectious Diseases ◽  
Drug Delivery Systems ◽  
Delivery Systems

scholarly journals Incorporation of Antibiotics into Solid Lipid Nanoparticles: A Promising Approach to Reduce Antibiotic Resistance Emergence

Nanomaterials ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1251
Author(s):  
Lide Arana ◽  
Lucia Gallego ◽  
Itziar Alkorta
Keyword(s):  
Drug Delivery ◽  
Antibiotic Resistance ◽  
Antimicrobial Resistance ◽  
Solid Lipid Nanoparticles ◽  
Drug Delivery Systems ◽  
Lipid Nanoparticles ◽  
Resistance Mechanisms ◽  
Delivery Systems ◽  
Solid Lipid Nanoparticle ◽  
Solid Lipid

Antimicrobial resistance is one of the biggest threats to global health as current antibiotics are becoming useless against resistant infectious pathogens. Consequently, new antimicrobial strategies are urgently required. Drug delivery systems represent a potential solution to improve current antibiotic properties and reverse resistance mechanisms. Among different drug delivery systems, solid lipid nanoparticles represent a highly interesting option as they offer many advantages for nontoxic targeted drug delivery. Several publications have demonstrated the capacity of SLNs to significantly improve antibiotic characteristics increasing treatment efficiency. In this review article, antibiotic-loaded solid lipid nanoparticle-related works are analyzed to summarize all information associated with applying these new formulations to tackle the antibiotic resistance problem. The main antimicrobial resistance mechanisms and relevant solid lipid nanoparticle characteristics are presented to later discuss the potential of these nanoparticles to improve current antibiotic treatment characteristics and overcome antimicrobial resistance mechanisms. Moreover, solid lipid nanoparticles also offer new possibilities for other antimicrobial agents that cannot be administrated as free drugs. The advantages and disadvantages of these new formulations are also discussed in this review. Finally, given the progress of the studies carried out to date, future directions are discussed.

Antimicrobial Resistance and Antimicrobial Nanomaterials

2021 ◽  
pp. 1-28
Author(s):  
Muthupandian Saravanan ◽  
Melaku Ashagrie Belete ◽  
Selam Niguse ◽  
Ephrem Tsegay ◽  
Tadele Araya ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Antimicrobial Resistance ◽  
Drug Delivery Systems ◽  
New Technology ◽  
Modern Medicine ◽  
Delivery Systems ◽  
Inorganic Nanoparticles ◽  
Social Burden ◽  
Conventional Drug ◽  
Global Issue

Back in the mid-nineties, the discovery of antimicrobials denoted a profound and remarkable achievement in medicine which was capable of saving lives. However, recently, antimicrobial resistance became a major global issue facing modern medicine and significantly increased among bacteria, fungi, and viruses which results in reduced efficacy of many clinically important and lifesaving antimicrobials. The growing rise of antimicrobial resistance inflicts a remarkable economic and social burden on the health care system globally. The replacement of conventional antimicrobials by new technology to counteract and lessen antimicrobial resistance is currently ongoing. Nanotechnology is an advanced approach to overcome challenges of such resisted conventional drug delivery systems mainly based on the development and fabrication of nanoparticulate structures. Numerous forms of nanoparticulate systems have been discovered and tried as prospective drug delivery systems, comprising organic and inorganic nanoparticles.

scholarly journals Emerging Applications of Drug Delivery Systems in Oral Infectious Diseases Prevention and Treatment

Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 516 ◽  
Author(s):  
Jingou Liang ◽  
Xinyu Peng ◽  
Xuedong Zhou ◽  
Jing Zou ◽  
Lei Cheng
Keyword(s):  
Drug Delivery ◽  
Infectious Diseases ◽  
Drug Delivery Systems ◽  
Oral Drug Delivery ◽  
Oral Candidiasis ◽  
Delivery Systems ◽  
Oral Drug ◽  
Oral Microbiota ◽  
Stimuli Responsive

The oral cavity is a unique complex ecosystem colonized with huge numbers of microorganism species. Oral cavities are closely associated with oral health and sequentially with systemic health. Many factors might cause the shift of composition of oral microbiota, thus leading to the dysbiosis of oral micro-environment and oral infectious diseases. Local therapies and dental hygiene procedures are the main kinds of treatment. Currently, oral drug delivery systems (DDS) have drawn great attention, and are considered as important adjuvant therapy for oral infectious diseases. DDS are devices that could transport and release the therapeutic drugs or bioactive agents to a certain site and a certain rate in vivo. They could significantly increase the therapeutic effect and reduce the side effect compared with traditional medicine. In the review, emerging recent applications of DDS in the treatment for oral infectious diseases have been summarized, including dental caries, periodontitis, peri-implantitis and oral candidiasis. Furthermore, oral stimuli-responsive DDS, also known as “smart” DDS, have been reported recently, which could react to oral environment and provide more accurate drug delivery or release. In this article, oral smart DDS have also been reviewed. The limits have been discussed, and the research potential demonstrates good prospects.

Design of smart targeted and responsive drug delivery systems with enhanced antibacterial properties

Nanoscale ◽  
2018 ◽  
Vol 10 (45) ◽  
pp. 20946-20962 ◽  
Author(s):  
Hao Chen ◽  
Yingying Jin ◽  
Jingjie Wang ◽  
Yuqin Wang ◽  
Wenya Jiang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Infectious Diseases ◽  
Drug Delivery Systems ◽  
Antibacterial Properties ◽  
Delivery Systems ◽  
The Past

The use of antibiotics has been an epoch-making invention in the past few decades for the treatment of infectious diseases.

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