A metformin-based nanoreactor alleviates hypoxia and reduces ATP for cancer synergistic therapy

2021 ◽  
Author(s):  
Xiangyu Meng ◽  
Jia Song ◽  
Yunfeng Lei ◽  
Xuezhong Zhang ◽  
Zhixin Chen ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Photothermal Therapy ◽  
Tumor Therapy

A metformin-based smart responsive gelatin nanoreactor enhances hypoxia-limited photodynamic therapy and amplifies ATP-inhibited photothermal therapy for synergistic tumor therapy.

Low-work-function LaB6 for realizing photodynamic-enhanced photothermal therapy

2021 ◽  
Author(s):  
Shuanglong Tang ◽  
Weicheng Huang ◽  
Yan Gao ◽  
Na An ◽  
Yadong Wu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Work Function ◽  
Photothermal Therapy ◽  
Tumor Therapy ◽  
Single Material

Photodynamic therapy (PDT) enhanced photothermal therapy (PTT) shows great significance towards tumor therapy, especially for the single material mediated process that could greatly simplify the experimental arrangements. This study presents...

Palladium Cube with Pt Shell Deposition for Localized Surface Plasmon Resonance Enhanced Photodynamic and Photothermal Therapy of Hypoxic Tumor

2021 ◽  
Author(s):  
Wenxiang Gu ◽  
Zhiyuan Hua ◽  
Zheng Li ◽  
Zhiheng Cai ◽  
Wandong Wang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Surface Plasmon Resonance ◽  
Tumor Microenvironment ◽  
Localized Surface Plasmon Resonance ◽  
Photothermal Therapy ◽  
Tumor Therapy ◽  
Localized Surface Plasmon ◽  
Shell Deposition ◽  
Hypoxic Tumor ◽  
Solid Tumor Therapy

Multifunctional phototherapy nanoagents for imaging-guided synergistic photothermal therapy (PTT) and photodynamic therapy (PDT) are highly desirable in the field of solid tumor therapy. Nevertheless, the tumor microenvironment (TME) inherently charactered...

Photoactive conjugated polymer/graphdiyne nanocatalyst for CO2 reduce into CO in living cells for hypoxia tumor treatment

2021 ◽  
Author(s):  
Endong Zhang ◽  
Zicheng Zuo ◽  
Wen Yu ◽  
Hao Zhao ◽  
Shengpeng Xia ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Photodynamic Therapy ◽  
Tumor Microenvironment ◽  
Conjugated Polymer ◽  
Tumor Therapy ◽  
Living Cells ◽  
Tumor Treatment ◽  
Treatment Efficiency ◽  
Therapy Strategy ◽  
Co Gas

Carbon monoxide (CO) gas therapy has grown to be an emerging tumor therapy strategy to avoid low treatment efficiency of photodynamic therapy (PDT) caused by the hypoxia tumor microenvironment. However,...

scholarly journals Organic dots (O-dots) for theranostic applications: preparation and surface engineering

RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2253-2291
Author(s):  
Amin Shiralizadeh Dezfuli ◽  
Elmira Kohan ◽  
Sepand Tehrani Fateh ◽  
Neda Alimirzaei ◽  
Hamidreza Arzaghi ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Photodynamic Therapy ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Surface Engineering ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Cargo Delivery ◽  
Bio Imaging ◽  
Theranostic Applications

Organic dots is a term used to represent materials including graphene quantum dots and carbon quantum dots because they rely on the presence of other atoms (O, H, and N) for their photoluminescence or fluorescence properties. Cargo delivery, bio-imaging, photodynamic therapy and photothermal therapy are major biomedical applications of organic dots.

Phototherapy and multimodal imaging of cancers based on perfluorocarbon nanomaterials

2021 ◽  
Author(s):  
Zhaoguo Han ◽  
xianshuang tu ◽  
Lina Qiao ◽  
Yige Sun ◽  
Zibo Li ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Side Effects ◽  
Cancer Treatment ◽  
Photothermal Therapy ◽  
Multimodal Imaging

Phototherapy, such as photodynamic therapy (PDT) and photothermal therapy (PTT) possesses unique characteristics of non-invasiveness and minimal side effects in cancer treatment, compared with conventional therapies. However, the ubiquitous tumor...

scholarly journals Photo-Based Nanomedicines Using Polymeric Systems in the Field of Cancer Imaging and Therapy

Biomedicines ◽  
2020 ◽  
Vol 8 (12) ◽  
pp. 618
Author(s):  
Patihul Husni ◽  
Yuseon Shin ◽  
Jae Chang Kim ◽  
Kioh Kang ◽  
Eun Seong Lee ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Optical Imaging ◽  
Photothermal Therapy ◽  
Cancer Imaging ◽  
Polymeric Systems ◽  
Therapeutic Applications ◽  
Shed Light

The use of photo-based nanomedicine in imaging and therapy has grown rapidly. The property of light in converting its energy into different forms has been exploited in the fields of optical imaging (OI) and phototherapy (PT) for diagnostic and therapeutic applications. The development of nanotechnology offers numerous advantages to overcome the challenges of OI and PT. Accordingly, in this review, we shed light on common photosensitive agents (PSAs) used in OI and PT; these include fluorescent and bioluminescent PSAs for OI or PT agents for photodynamic therapy (PDT) and photothermal therapy (PTT). We also describe photo-based nanotechnology systems that can be used in photo-based diagnostics and therapies by using various polymeric systems.

Cascade Tumor Therapy Platform for Sensitized Chemotherapy and Penetration Enhanced Photothermal Therapy

2021 ◽  
pp. 2100429
Author(s):  
Sen Liu ◽  
Can Shen ◽  
Dongsheng Jiang ◽  
Cheng Qian ◽  
Zhongmei Yang ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Tumor Therapy

scholarly journals Recent progress in the development of near-infrared organic photothermal and photodynamic nanotherapeutics

2018 ◽  
Vol 6 (4) ◽  
pp. 746-765 ◽  
Author(s):  
Houjuan Zhu ◽  
Penghui Cheng ◽  
Peng Chen ◽  
Kanyi Pu
Keyword(s):  
Photodynamic Therapy ◽  
Side Effects ◽  
Spatial Resolution ◽  
Photothermal Therapy ◽  
Normal Tissue ◽  
Recent Progress ◽  
Near Infrared ◽  
Tumor Ablation ◽  
Ablation Efficiency ◽  
Excellent Spatial Resolution

Phototherapies including photothermal therapy (PTT) and photodynamic therapy (PDT) have gained considerable attention due to their high tumor ablation efficiency, excellent spatial resolution and minimal side effects on normal tissue.

scholarly journals A covalent organic framework as a nanocarrier for synergistic phototherapy and immunotherapy

2020 ◽  
Vol 8 (25) ◽  
pp. 5451-5459 ◽  
Author(s):  
Ying Zhou ◽  
Sainan Liu ◽  
Chunling Hu ◽  
Lihan Cai ◽  
Maolin Pang
Keyword(s):  
Photodynamic Therapy ◽  
Local Recurrence ◽  
Cancer Treatment ◽  
Photothermal Therapy ◽  
Tumor Metastasis ◽  
Primary Tumors ◽  
Treatment Methods ◽  
Covalent Organic Framework ◽  
Organic Framework

As traditional cancer treatment methods, photodynamic therapy (PDT) and photothermal therapy (PTT) can eliminate primary tumors, but they cannot inhibit extensive tumor metastasis and local recurrence.

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