Construction of triple non-covalent interaction-based ultra-strong self-healing polymeric gels via frontal polymerization

2020 ◽  
Vol 8 (40) ◽  
pp. 14083-14091
Author(s):  
Ji-Dong Liu ◽  
Xiang-Yun Du ◽  
Cai-Feng Wang ◽  
Qing Li ◽  
Su Chen
Keyword(s):  
Frontal Polymerization ◽  
Self Healing ◽  
Smart Window ◽  
Covalent Interaction ◽  
Polymeric Gels ◽  
Non Covalent Interactions ◽  
Covalent Interactions

Robust and self-healing polymeric gels based on triple non-covalent interactions have been constructed for generation of a new self-healing thermoresponsive smart window.

Three-dimensional protein assemblies directed by orthogonal non-covalent interactions

2016 ◽  
Vol 52 (62) ◽  
pp. 9687-9690 ◽  
Author(s):  
Guang Yang ◽  
Zdravko Kochovski ◽  
Zhongwei Ji ◽  
Yan Lu ◽  
Guosong Chen ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Protein Assemblies ◽  
Covalent Interaction ◽  
Specific Recognition ◽  
Non Covalent Interactions ◽  
Interaction Strategy ◽  
Covalent Interactions

In this report, an orthogonal non-covalent interaction strategy based on specific recognition between sugar and protein, and host–guest interaction, was employed to construct artificial three dimensional (3D) protein assemblies in the laboratory.

scholarly journals Self-Healing Hydrogels: Preparation, Mechanism and Advancement in Biomedical Applications

Polymers ◽  
2021 ◽  
Vol 13 (21) ◽  
pp. 3782
Author(s):  
Anupama Devi V. K. ◽  
Rohin Shyam ◽  
Arunkumar Palaniappan ◽  
Amit Kumar Jaiswal ◽  
Tae-Hwan Oh ◽  
...  
Keyword(s):  
Composite Materials ◽  
Biomedical Applications ◽  
Cell Encapsulation ◽  
Self Healing ◽  
3D Bioprinting ◽  
Engineering Systems ◽  
Future Perspectives ◽  
Non Covalent Interactions ◽  
Polymeric Hydrogels ◽  
Covalent Interactions

Polymeric hydrogels are widely explored materials for biomedical applications. However, they have inherent limitations like poor resistance to stimuli and low mechanical strength. This drawback of hydrogels gave rise to ‘’smart self-healing hydrogels’’ which autonomously repair themselves when ruptured or traumatized. It is superior in terms of durability and stability due to its capacity to reform its shape, injectability, and stretchability thereby regaining back the original mechanical property. This review focuses on various self-healing mechanisms (covalent and non-covalent interactions) of these hydrogels, methods used to evaluate their self-healing properties, and their applications in wound healing, drug delivery, cell encapsulation, and tissue engineering systems. Furthermore, composite materials are used to enhance the hydrogel’s mechanical properties. Hence, findings of research with various composite materials are briefly discussed in order to emphasize the healing capacity of such hydrogels. Additionally, various methods to evaluate the self-healing properties of hydrogels and their recent advancements towards 3D bioprinting are also reviewed. The review is concluded by proposing several pertinent challenges encountered at present as well as some prominent future perspectives.

Robust Supramolecular Nano-Tunnels Built from Molecular Bricks

2020 ◽  
Author(s):  
Peifa Wei ◽  
Zheng Zheng ◽  
Junyi Gong ◽  
Jun Zhang ◽  
Herman H.-Y. Sung ◽  
...  
Keyword(s):  
Single Crystal ◽  
Organic Molecules ◽  
Co2 Adsorption ◽  
Linear Molecule ◽  
Self Healing ◽  
Pi Stacking ◽  
New Methods ◽  
Hydrogen Bonding Interactions ◽  
Non Covalent Interactions ◽  
Covalent Interactions

Chemists are always seeking new methods to construct porous lattice frameworks using simple motifs as the impetus. Different from the extensively reported frameworks which were stabilized by extended bonding, porous crystals of discrete organic molecules is an emerging area of porous materials with dynamic and flexible conformation, consisting exclusively of non-covalent interactions. Herein we report geometrically simple linear molecule that assemble into a supramolecular nano-tunnel through synergy of anionic trident and multiple intermolecular pi-pi stacking interactions. The nano-tunnel crystal exhibit exceptional chemical stability in concentrated HCl and NaOH aqueous solutions, which is rarely been seen in supramolecular organic frameworks and often related to designed extensive hydrogen bonding interactions. Upon thermal treatment, the formed nano-tunnel crystals go through multistage single-crystal-to-single-crystal phase transformations accompanied by thermosalient effect. Aggregation-induced emission joins with the adaptive pores render the crystals with responsive fluorescent change from blue to yellow and visible self-healing porosity transformation upon being stimulated. Furthermore, the desolvated pores exhibit highly selective CO2 adsorption at ambient temperature. <br>

scholarly journals Non-covalent Interaction With SUMO Enhances the Activity of Human Cytomegalovirus Protein IE1

2021 ◽  
Vol 9 ◽  
Author(s):  
Vasvi Tripathi ◽  
Kiran Sankar Chatterjee ◽  
Ranabir Das
Keyword(s):  
Human Cytomegalovirus ◽  
Core Domain ◽  
Promyelocytic Leukemia Protein ◽  
Covalent Interaction ◽  
Transactivation Activity ◽  
Early Protein ◽  
Viral Promoters ◽  
Non Covalent Interactions ◽  
Cellular Pathways ◽  
Covalent Interactions

Viruses interact with the host cellular pathways to optimize cellular conditions for replication. The Human Cytomegalovirus (HCMV) Immediate-Early protein 1 (IE1) is the first viral protein to express during infection. It is a multifunctional and conditionally essential protein for HCMV infection. SUMO signaling regulates several cellular pathways that are also targets of IE1. Consequently, IE1 exploits SUMO signaling to regulate these pathways. The covalent interaction of IE1 and SUMO (IE1-SUMOylation) is well studied. However, the non-covalent interactions between SUMO and IE1 are unknown. We report two SUMO-Interacting Motifs (SIMs) in IE1, one at the end of the core domain and another in the C-terminal domain. NMR titrations showed that IE1-SIMs bind to SUMO1 but not SUMO2. Two critical functions of IE1 are inhibition of SUMOylation of Promyelocytic leukemia protein (PML) and transactivation of viral promoters. Although the non-covalent interaction of IE1 and SUMO is not involved in the inhibition of PML SUMOylation, it contributes to the transactivation activity. The transactivation activity of IE1 was previously correlated to its ability to inhibit PML SUMOylation. Our results suggest that transactivation and inhibition of PML SUMOylation are independent activities of IE1.

Non-covalent interactions with inverted carbon: a carbo-hydrogen bond or a new type of hydrogen bond?

2020 ◽  
Vol 22 (16) ◽  
pp. 8988-8997 ◽  
Author(s):  
Juhi Dutta ◽  
Dipak Kumar Sahoo ◽  
Subhrakant Jena ◽  
Kiran Devi Tulsiyan ◽  
Himansu S. Biswal
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bond ◽  
Quantum Chemical Calculations ◽  
Structure Analysis ◽  
Quantum Chemical ◽  
Crystal Structure Analysis ◽  
Covalent Interaction ◽  
New Type ◽  
Non Covalent Interactions ◽  
Covalent Interactions

Crystal structure analysis and quantum chemical calculations enabled us to discover a new non-covalent interaction, coined as carbo-hydrogen bond (CH-bond).

scholarly journals 3D-printable self-healing and mechanically reinforced hydrogels with host–guest non-covalent interactions integrated into covalently linked networks

2019 ◽  
Vol 6 (4) ◽  
pp. 733-742 ◽  
Author(s):  
Zhifang Wang ◽  
Geng An ◽  
Ye Zhu ◽  
Xuemin Liu ◽  
Yunhua Chen ◽  
...  
Keyword(s):  
Mechanical Strength ◽  
Self Healing ◽  
Crosslinked Networks ◽  
Non Covalent Interactions ◽  
Covalently Linked ◽  
Covalent Interactions

Novel 3D-printable hydrogels with host–guest non-covalent interactions and covalently crosslinked networks show robust mechanical strength, self-healing performance and excellent biocompatibility.

The structure–property relationship in LAPONITE® materials: from Wigner glasses to strong self-healing hydrogels formed by non-covalent interactions

Soft Matter ◽  
2019 ◽  
Vol 15 (6) ◽  
pp. 1278-1289 ◽  
Author(s):  
Tiago B. Becher ◽  
Carolyne B. Braga ◽  
Diego L. Bertuzzi ◽  
Miguel D. Ramos ◽  
Ayaz Hassan ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Self Healing ◽  
Structure Property ◽  
Potential Measurement ◽  
Absorbance Spectroscopy ◽  
Structure Property Relationship ◽  
Non Covalent Interactions ◽  
Covalent Interactions ◽  
Scanning Electron

Rheology, SAXS, and dynamic light scattering (DLS) analysis, zeta potential measurement, scanning electron microscopy (SEM), and micro-FTIR and absorbance spectroscopy were used to enlighten the controversial literature about LAPONITE® materials.

The role of non-covalent interactions in the self-healing mechanism of disulfide-based polymers

2017 ◽  
Vol 19 (28) ◽  
pp. 18461-18470 ◽  
Author(s):  
Elena Formoso ◽  
José M. Asua ◽  
Jon M. Matxain ◽  
Fernando Ruipérez
Keyword(s):  
The Self ◽  
Self Healing ◽  
Non Covalent Interactions ◽  
Covalent Interactions

We have established a theoretical protocol with the aim of predicting the self-healing capacity of disulfides and related materials.

Biocompatible double network poly(acrylamide-co-acrylic acid)–Al3+/poly(vinyl alcohol)/graphene oxide nanocomposite hydrogels with excellent mechanical properties, self-recovery and self-healing ability

2020 ◽  
Vol 44 (25) ◽  
pp. 10390-10403
Author(s):  
Zhanxin Jing ◽  
Xueying Xian ◽  
Qiuhong Huang ◽  
Qiurong Chen ◽  
Pengzhi Hong ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Graphene Oxide ◽  
Acrylic Acid ◽  
Poly Vinyl Alcohol ◽  
Self Healing ◽  
Double Network ◽  
Nanocomposite Hydrogels ◽  
Non Covalent Interactions ◽  
Covalent Interactions ◽  
Poly Acrylamide

Biocompatible double network PAmAA–Al3+/PVA/GO nanocomposite hydrogels based on non-covalent interactions were synthesized, and the non-covalent interactions endow the materials with good self-recovery and self-healing performances.

Self-healing and shape-memory properties of polymeric materials cross-linked by hydrogen bonding and metal–ligand interactions

2019 ◽  
Vol 10 (33) ◽  
pp. 4519-4523 ◽  
Author(s):  
Yuichiro Kobayashi ◽  
Tomohiro Hirase ◽  
Yoshinori Takashima ◽  
Akira Harada ◽  
Hiroyasu Yamaguchi
Keyword(s):  
Hydrogen Bonding ◽  
Shape Memory ◽  
Polymeric Materials ◽  
Cross Linking ◽  
Self Healing ◽  
Shape Memory Properties ◽  
Ligand Interactions ◽  
Non Covalent Interactions ◽  
Covalent Interactions ◽  
Metal Ligand

Polymeric materials were prepared by cross-linking them with two independent non-covalent interactions, namely hydrogen bonding and metal–ligand interactions.

Sign in / Sign up

Export Citation Format

Share Document