A lysosome-targeting viscosity-sensitive fluorescent probe based on a novel functionalised near-infrared xanthene-indolium dye and its application in living cells

2020 ◽  
Vol 8 (38) ◽  
pp. 8838-8844
Author(s):  
Chang Liu ◽  
Tong Zhao ◽  
Song He ◽  
Liancheng Zhao ◽  
Xianshun Zeng

The viscosity of lysosomes plays a significant role in modulating biological processes and reflects the status and function of this kind of organelle, e.g., locations, morphologies, and components.

2021 ◽  
Author(s):  
Bochao Chen ◽  
Shumei Mao ◽  
Yanyan Sun ◽  
Liyuan Sun ◽  
Ning Ding ◽  
...  

A mitochondria-targeted near-infrared fluorescent probe NIR-V with 700 nm emission was designed to monitor cell viscosity changes, which was applied to detect the intracellular viscosity and imagine pancreatic tissue in diabetic mouse model.


2021 ◽  
Author(s):  
Qiaomei Yang ◽  
Liyi Zhou ◽  
Longpeng Peng ◽  
Gangqiang Yuan ◽  
Haiyuan Ding ◽  
...  

Hydrogen sulfide (H2S) is one of the important gaseous signal molecules and plays key roles in various biologically crucial processes. In this work, we report a novel two-photon near-infrared (TP-NIR)...


2017 ◽  
Vol 468 ◽  
pp. 140-145 ◽  
Author(s):  
Jianheng Bi ◽  
Mingxi Fang ◽  
Jianbo Wang ◽  
Shuai Xia ◽  
Yibin Zhang ◽  
...  

2020 ◽  
Vol 310 ◽  
pp. 127839 ◽  
Author(s):  
Sathyadevi Palanisamy ◽  
Li-Fong Chen ◽  
Shey-Cherng Tzou ◽  
Yun-Ming Wang

2014 ◽  
Vol 175 (3) ◽  
pp. 1644-1650 ◽  
Author(s):  
Chunlong Sun ◽  
Jin Cai ◽  
Junqing Chen ◽  
Yang Wu ◽  
Peng Wang ◽  
...  

2018 ◽  
Vol 6 (27) ◽  
pp. 4466-4473 ◽  
Author(s):  
Junfeng Miao ◽  
Yingying Huo ◽  
Hu Shi ◽  
Junru Fang ◽  
Juanjuan Wang ◽  
...  

An aromatic tertiary amine-functionalized Si-rhodamine dye has been exploited as a near-infrared fluorescent probe for visualizing endogenous peroxynitrite in living cells, tissues, and mice.


The Analyst ◽  
2019 ◽  
Vol 144 (24) ◽  
pp. 7390-7397 ◽  
Author(s):  
Hefang Ji ◽  
Xiuxuan Zhang ◽  
Yanpeng Dai ◽  
Tianzi Xue ◽  
Saima Misal ◽  
...  

Real-time monitoring of the cytochrome P450 1A1 (CYP1A1) activity in complex biological systems via a practical tool is highly sought after because of its significant role in the metabolism and bioactivation of various xenobiotics.


2020 ◽  
Vol 11 (6) ◽  
pp. 1617-1622 ◽  
Author(s):  
Xiaoyi Li ◽  
Xiaohua Li ◽  
Huimin Ma

A near-infrared mitochondria-targeting fluorescent probe has been developed to monitor the mitophagy-specific polarity dynamics in living cells.


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