scholarly journals A near-infrared fluorescent probe reveals decreased mitochondrial polarity during mitophagy

2020 ◽  
Vol 11 (6) ◽  
pp. 1617-1622 ◽  
Author(s):  
Xiaoyi Li ◽  
Xiaohua Li ◽  
Huimin Ma

A near-infrared mitochondria-targeting fluorescent probe has been developed to monitor the mitophagy-specific polarity dynamics in living cells.

2021 ◽  
Author(s):  
Qiaomei Yang ◽  
Liyi Zhou ◽  
Longpeng Peng ◽  
Gangqiang Yuan ◽  
Haiyuan Ding ◽  
...  

Hydrogen sulfide (H2S) is one of the important gaseous signal molecules and plays key roles in various biologically crucial processes. In this work, we report a novel two-photon near-infrared (TP-NIR)...


2017 ◽  
Vol 89 (3) ◽  
pp. 1787-1792 ◽  
Author(s):  
Xiaojun Liu ◽  
Aishan Zheng ◽  
Dongrui Luan ◽  
Xiaoting Wang ◽  
Fanpeng Kong ◽  
...  

Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 437 ◽  
Author(s):  
Ismail Ismail ◽  
Zhuoyue Chen ◽  
Xiuru Ji ◽  
Lu Sun ◽  
Long Yi ◽  
...  

Near-infrared (NIR) fluorescent probes are attractive tools for bioimaging applications because of their low auto-fluorescence interference, minimal damage to living samples, and deep tissue penetration. H2S is a gaseous signaling molecule that is involved in redox homeostasis and numerous biological processes in vivo. To this end, we have developed a new red shifted fluorescent probe 1 to detect physiological H2S in live cells. The probe 1 is based on a rhodamine derivative as the red shifted fluorophore and the thiolysis of 7-nitro 1,2,3-benzoxadiazole (NBD) amine as the H2S receptor. The probe 1 displays fast fluorescent enhancement at 660 nm (about 10-fold turn-ons, k2 = 29.8 M−1s−1) after reacting with H2S in buffer (pH 7.4), and the fluorescence quantum yield of the activated red shifted product can reach 0.29. The probe 1 also exhibits high selectivity and sensitivity towards H2S. Moreover, 1 is cell-membrane-permeable and mitochondria-targeting, and can be used for imaging of endogenous H2S in living cells. We believe that this red shifted fluorescent probe can be a useful tool for studies of H2S biology.


Talanta ◽  
2019 ◽  
Vol 197 ◽  
pp. 326-333 ◽  
Author(s):  
Xiong-jie Zhao ◽  
Yu-ting Li ◽  
Yu-ren Jiang ◽  
Bing-qing Yang ◽  
Ce Liu ◽  
...  

2021 ◽  
Author(s):  
Bochao Chen ◽  
Shumei Mao ◽  
Yanyan Sun ◽  
Liyuan Sun ◽  
Ning Ding ◽  
...  

A mitochondria-targeted near-infrared fluorescent probe NIR-V with 700 nm emission was designed to monitor cell viscosity changes, which was applied to detect the intracellular viscosity and imagine pancreatic tissue in diabetic mouse model.


2017 ◽  
Vol 468 ◽  
pp. 140-145 ◽  
Author(s):  
Jianheng Bi ◽  
Mingxi Fang ◽  
Jianbo Wang ◽  
Shuai Xia ◽  
Yibin Zhang ◽  
...  

2020 ◽  
Vol 310 ◽  
pp. 127839 ◽  
Author(s):  
Sathyadevi Palanisamy ◽  
Li-Fong Chen ◽  
Shey-Cherng Tzou ◽  
Yun-Ming Wang

2014 ◽  
Vol 175 (3) ◽  
pp. 1644-1650 ◽  
Author(s):  
Chunlong Sun ◽  
Jin Cai ◽  
Junqing Chen ◽  
Yang Wu ◽  
Peng Wang ◽  
...  

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