In situ and non-cytotoxic cross-linking strategy for 3D printable biomaterials

Soft Matter ◽  
2021 ◽  
Author(s):  
Yiğitcan Sümbelli ◽  
Sibel Emir Diltemiz ◽  
Mehmet Girayhan Say ◽  
Özlem Biçen Ünlüer ◽  
Arzu Ersöz ◽  
...  

A new cross-linking method maintaining structural stability and elastic properties.

2020 ◽  
Vol 11 (22) ◽  
pp. 3654-3672 ◽  
Author(s):  
Wen-Jian Zhang ◽  
Jamshid Kadirkhanov ◽  
Chang-Hui Wang ◽  
Sheng-Gang Ding ◽  
Chun-Yan Hong ◽  
...  

This review discusses the strategies of core-cross-linking in most of the PISA literatures (including post-polymerization cross-linking, photo-cross-linking and in situ cross-linking) and the applications of the cross-linked nano-objects.


2016 ◽  
Vol 22 (6) ◽  
pp. 947-955 ◽  
Author(s):  
Yigong Liu ◽  
Qudus Hamid ◽  
Jessica Snyder ◽  
Chengyang Wang ◽  
Wei Sun

Purpose This paper aims to present a solid freeform fabrication-based in situ three-dimensional (3D) printing method. This method enables simultaneous cross-linking alginate at ambient environmental conditions (temperature and pressure) for 3D-laden construct fabrication. The fabrication feasibility and potentials in biomedical applications were evaluated. Design/methodology/approach Fabrication feasibility was evaluated as the investigation of fabrication parameters on strut formability (the capability to fabricate a cylindrical strut in the same diameter as dispensing tip) and structural stability (the capability to hold the fabricated 3D-laden construct against mechanical disturbance). Potentials in biomedical application was evaluated as the investigation on structural integrity (the capability to preserve the fabricated 3D-laden construct in cell culture condition). Findings Strut formability can be achieved when the flow rate of alginate suspension and nozzle travel speed are set according to the dispensing tip size, and extruded alginate was cross-linked sufficiently. A range of cross-linking-related fabrication parameters was determined for sufficient cross-link. The structural stability and structural integrity were found to be controlled by alginate composition. An optimized setting of the alginate composition and the fabrication parameters was determined for the fabrication of a desired stable scaffold with structural integrity for 14 days. Originality/value This paper reports that in situ 3D printing is an efficient method for 3D-laden construct fabrication and its potentials in biomedical application.


Author(s):  
М. Раранський ◽  
В. Балазюк ◽  
М. Мельник ◽  
О. Горда ◽  
М. Гунько

InfoMat ◽  
2021 ◽  
Author(s):  
Ramin Rojaee ◽  
Samuel Plunkett ◽  
Md Golam Rasul ◽  
Meng Cheng ◽  
Vahid Jabbari ◽  
...  

2012 ◽  
Vol 12 (9) ◽  
pp. 1220-1231 ◽  
Author(s):  
Adrian Sulistio ◽  
Anton Blencowe ◽  
Jiapei Wang ◽  
Gary Bryant ◽  
Xiaoqing Zhang ◽  
...  
Keyword(s):  

2018 ◽  
Vol 42 (13) ◽  
pp. 11023-11030 ◽  
Author(s):  
Lulu Liang ◽  
Li Nie ◽  
Minjuan Jiang ◽  
Fusheng Bie ◽  
Linjun Shao ◽  
...  

Chitosan composite superfine fibers with a diameter of 321 ± 99 nm were prepared by electrospinning with PEO as the co-spinning polymer and itaconic acid as the in situ cross-linking agent.


2014 ◽  
Vol 126 (1) ◽  
pp. 66-67
Author(s):  
S. Michalik ◽  
J. Bednarcik ◽  
P. Pawlik ◽  
R. Matija ◽  
P. Sovak

2018 ◽  
Vol 57 (50) ◽  
pp. 17048-17057 ◽  
Author(s):  
Yanping Huang ◽  
Nianhua Dan ◽  
Weihua Dan ◽  
Weifeng Zhao ◽  
Zhongxiang Bai ◽  
...  

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