scholarly journals A rationally designed peptoid for the selective chelation of Zn2+ over Cu2+

2020 ◽  
Vol 11 (37) ◽  
pp. 10127-10134
Author(s):  
Pritam Ghosh ◽  
Galia Maayan
Keyword(s):  
Simulated Body Fluid ◽  
Metal Ions ◽  
Body Fluid ◽  
Zinc Protein

A peptoid trimer incorporating picolyl 2,2′:6′,2′′-terpyridine can selectively bind Zn2+ ions in the presence of excess Cu2+ ions and other metal ions, in water and in simulated body fluid (SBF) and can remove Zn2+ from a natural zinc protein in SBF.

scholarly journals Metal ions leachables from fake orthodontic braces incubated in simulated body fluid

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Riyam Haleem ◽  
Noor Ayuni Ahmad Shafiai ◽  
Siti Noor Fazliah Mohd Noor
Keyword(s):  
Simulated Body Fluid ◽  
Metal Ions ◽  
Inductively Coupled Plasma ◽  
Metal Ion ◽  
Body Fluid ◽  
Atomic Emission ◽  
Analysis Data ◽  
Inductively Coupled ◽  
Significant Release ◽  
Control Samples

Abstract Background The demand for fake braces usage in Southeast Asia are increasing but lack of certification and information on fake braces as medical devices from regulated bodies raised a concern towards its safety. The aim of this study was to determine the types of metal ion leachable from removable fake braces based on heavy metal ions present in metallic materials, immersed in simulated body fluid (SBF) and analysed using inductively coupled plasma atomic emission spectroscopy. Methods Three sets of fake braces and one control were dissembled to only their brackets and archwires and immersed separately in SBF. They were placed in an incubator shaker at a temperature of 37 °C at 50 rpm. A 3.0 ml measurement of SBF was taken out from the sample containers at days 7, 14 and 28 and kept at − 20 °C for further analysis. Data were analysed using SPSS version 26.0 (IBM, Armonk, USA) (P < 0.05). Descriptive and one-way ANOVA analyses with Bonferroni post hoc tests were used to assess the significant differences between the metal ions released in SBF from the control samples and fake braces. Results All 23 elements under investigation except Si ions were detected from the control samples and fake braces. There were significant increased K ions and reduced levels of Mg ions from the fake archwires and brackets. Most ions released were less than 10 mg/L (Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Mo, Cd, Pb, Al) or 1 mg/L (Li, Ba) into the SBF medium. Conclusion There were significant release of Ca and K ions from the fake samples. Elements such as Li, Ba, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Mo, Cd and Sb had increased in concentration at day 7 and the concentration plateaued until day 28.

IN-VITRO BEHAVIOUR OF BIPHASIC CALCIUM PHOSPHATE WITH DIFFERENT RATIO OF SILICA CONTENT IN SIMULATED BODY FLUID

2015 ◽  
Vol 23 (1) ◽  
pp. 1-14
Author(s):  
Sudirman Sahid ◽  
◽  
Nor Shahida Kader Bashah ◽  
Salina Sabudin ◽  
◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Biphasic Calcium Phosphate ◽  
Silica Content

Phase evolution of hydroxapatite coatings suspension plasma sprayed using variable parameters in simulated body fluid

2010 ◽  
Vol 204 (8) ◽  
pp. 1236-1246 ◽  
Author(s):  
Romain d'Haese ◽  
Lech Pawlowski ◽  
Muriel Bigan ◽  
Roman Jaworski ◽  
Marc Martel
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Phase Evolution ◽  
Variable Parameters ◽  
Plasma Sprayed

scholarly journals Tetracalcium Phosphate/Monetite/Calcium Sulfate Hemihdrate Biocement Powder Mixtures Prepared by the One-Step Synthesis for Preparation of Nanocrystalline Hydroxyapatite Biocement-Properties and In Vitro Evaluation

Materials ◽  
2021 ◽  
Vol 14 (9) ◽  
pp. 2137
Author(s):  
Lubomir Medvecky ◽  
Maria Giretova ◽  
Radoslava Stulajterova ◽  
Lenka Luptakova ◽  
Tibor Sopcak
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Calcium Sulfate ◽  
Powder Mixtures ◽  
Liquid Component ◽  
Tetracalcium Phosphate ◽  
Nanocrystalline Hydroxyapatite ◽  
One Step ◽  
Calcium Sulfate Hemihydrate

A modified one-step process was used to prepare tetracalcium phosphate/monetite/calcium sulfate hemihydrate powder cement mixtures (CAS). The procedure allowed the formation of monetite and calcium sulfate hemihydrate (CSH) in the form of nanoparticles. It was hypothesized that the presence of nanoCSH in small amounts enhances the in vitro bioactivity of CAS cement in relation to osteogenic gene markers in mesenchymal stem cells (MSCs). The CAS powder mixtures with 15 and 5 wt.% CSH were prepared by milling powder tetracalcium phosphate in an ethanolic solution of both orthophosphoric and sulfuric acids. The CAS cements had short setting times (around 5 min). The fast setting of the cement samples after the addition of the liquid component (water solution of NaH2PO4) was due to the partial formation of calcium sulfate dihydrate and hydroxyapatite before soaking in SBF with a small change in the original phase composition in cement powder samples after milling. Nanocrystalline hydroxyapatite biocement was produced by soaking of cement samples after setting in simulated body fluid (SBF). The fast release of calcium ions from CAS5 cement, as well as a small rise in the pH of SBF during soaking, were demonstrated. After soaking in SBF for 7 days, the final product of the cement transformation was nanocrystalline hydroxyapatite. The compressive strength of the cement samples (up to 30 MPa) after soaking in simulated body fluid (SBF) was comparable to that of bone. Real time polymerase chain reaction (RT-PCR) analysis revealed statistically significant higher gene expressions of alkaline phosphatase (ALP), osteonectin (ON) and osteopontin (OP) in cells cultured for 14 days in CAS5 extract compared to CSH-free cement. The addition of a small amount of nanoCSH (5 wt.%) to the tetracalcium phosphate (TTCP)/monetite cement mixture significantly promoted the over expression of osteogenic markers in MSCs. The prepared CAS powder mixture with its enhanced bioactivity can be used for bone defect treatment and has good potential for bone healing.

Surface-Directed Mineralization of Fibrous Collagen Scaffolds in Simulated Body Fluid for Tissue Engineering Applications

2021 ◽  
Vol 4 (3) ◽  
pp. 2514-2522
Author(s):  
Odair Bim-Júnior ◽  
Fabiana Curylofo-Zotti ◽  
Mariana Reis ◽  
Yvette Alania ◽  
Paulo N. Lisboa-Filho ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Collagen Scaffolds ◽  
Engineering Applications

scholarly journals Preparation and Degradation Characteristics of MAO/APS Composite Bio-Coating in Simulated Body Fluid

Coatings ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 667
Author(s):  
Zexin Wang ◽  
Fei Ye ◽  
Liangyu Chen ◽  
Weigang Lv ◽  
Zhengyi Zhang ◽  
...  
Keyword(s):  
Simulated Body Fluid ◽  
Composite Coating ◽  
Body Fluid ◽  
Composite Coatings ◽  
Degradation Process ◽  
Ceramic Coatings ◽  
Immersion Test ◽  
Substrate Material ◽  
Atmospheric Plasma

In this work, ZK60 magnesium alloy was employed as a substrate material to produce ceramic coatings, containing Ca and P, by micro-arc oxidation (MAO). Atmospheric plasma spraying (APS) was used to prepare the hydroxyapatite layer (HA) on the MAO coating to obtain a composite coating for better biological activity. The coatings were examined by various means including an X-ray diffractometer, a scanning electron microscope and an energy spectrometer. Meanwhile, an electrochemical examination, immersion test and tensile test were used to evaluate the in vitro performance of the composite coatings. The results showed that the composite coating has a better corrosion resistance. In addition, this work proposed a degradation model of the composite coating in the simulated body fluid immersion test. This model explains the degradation process of the MAO/APS coating in SBF.

scholarly journals Development of Adhesive, Bioactive and Antibacterial Titania Sol-Gel Coating on Titanium Substrate by Dip-Coating Technique

Coatings ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 243
Author(s):  
Diana Horkavcová ◽  
Quentin Doubet ◽  
Gisèle Laure Lecomte-Nana ◽  
Eva Jablonská ◽  
Aleš Helebrant
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Sol Gel ◽  
Titanium Substrate ◽  
Dip Coating ◽  
Coating Technique ◽  
Metal Implants ◽  
Excellent Adhesion ◽  
Titania Sol ◽  
Dip Coating Technique

The sol-gel method provides a wide variety of applications in the medical field. One of these applications is the formation of coatings on the metal implants. The coatings containing specific additive can enhance or improve the existing surface properties of the substrate. In this work, titania sol-gel coatings were doped with two forms of silver (AgNO3, Ag3PO4) and synthetic hydroxyapatite and applied on the titanium samples by dip-coating technique. After drying and slow firing, all coatings were characterized with scanning electron microscopy. Thin coatings were successfully prepared with excellent adhesion to the substrate (measured by ASTM D 3359-2), despite cracks. Coatings containing silver and hydroxyapatite demonstrated a 100% antibacterial effect against Escherichia coli after 24 h. The bioactivity of the coatings containing hydroxyapatite tested in modified simulated body fluid under static-dynamic conditions was confirmed by bone-like hydroxyapatite precipitation. To better understand the interaction of the coatings with simulated body fluid (SBF), changes of Ca2+ and (PO4)3− ions concentrations and pH values were studied.

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