Effects of Different Rare Earth Elements on the Degradation and Mechanical Properties of the ECAP Extruded Mg Alloys

Effects of different rare earth elements on the degradation and mechanical properties of the ECAP (equal channel angular pressing) extruded Mg alloys were investigated in this work. Microstructural characterization, thermodynamic calculation, a tensile test, an electrochemical test, an immersion test, a hydrogen evolution test and a cytotoxicity test were carried out. The results showed that yttrium addition was beneficial to the improvement of the alloy’s strength, and the ultimate tensile strength (UTS) and yield strength (YS) values of the ECAPed Mg-2Zn-0.5Y-0.5Zr alloy reached 315 MPa and 295 MPa, respectively. In addition, Nd was beneficial to the corrosion resistance, for which, the corrosion rate of the ECAPed Mg-2Zn-0.5Nd-0.5Zr alloy was observed to be 0.42 ± 0.04 mm/year in Hank’s solution after 14 days of immersion. Gd was moderate in improving both the corrosion resistance and mechanical properties. Moreover, after co-culturing with murine calvarial preosteoblasts (MC3T3-E1) cells, the ECAPed Mg-2Zn-0.5RE (Nd, Gd, Y)-0.5Zr alloys exhibited good cytocompatibility with a grade 1 cytotoxicity. Consequently, the ECAPed Mg-2Zn-0.5Nd-0.5Zr alloy showed the best application prospect in the field of orthopedics.

Fluoride Treatment and In Vitro Corrosion Behavior of Mg-Nd-Y-Zn-Zr Alloys Type

Fluoride conversion coatings on Mg present many advantages, among which one can find the reduction of the corrosion rate under “in vivo” or “in vitro” conditions and the promotion of the calcium phosphate deposition. Moreover, the fluoride ions released from MgF2 do not present cytotoxic effects and inhibit the biofilm formation, and thus these treated alloys are very suitable for cardiovascular stents and biodegradable orthopedic implants. In this paper, the biodegradation behavior of four new magnesium biodegradable alloys that have been developed in the laboratory conditions, before and after surface modifications by fluoride conversion (and sandblasting) coatings, are analyzed. We performed structural and surface analysis (XRD, SEM, contact angle) before and after applying different surface treatments. Furthermore, we studied the electrochemical behavior and biodegradation of all experimental samples after immersion test performed in NaCl solution. For a better evaluation, we also used LM and SEM for evaluation of the corroded samples after immersion test. The results showed an improved corrosion resistance for HF treated alloy in the NaCl solution. The chemical composition, uniformity, thickness and stability of the layers generated on the surface of the alloys significantly influence their corrosion behavior. Our study reveals that HF treatment is a beneficial way to improve the biofunctional properties required for the studied magnesium alloys to be used as biomaterials for manufacturing the orthopedic implants.

KARAKTERISTIK MARSHALL KERAMIK SEBAGAI AGREGAT HALUS DAN FILLER PADA CAMPURAN HOT ROLLER SHEET (HRS)

Penelitian ini mengenai pemanfaatan bahan sisa keramik pada pemasangan lantai rumah sebagai agregat halus dan filler dalam pembuatan lapis perkerasan aspal. Sebagai bahan agregat halus dan filler, keramik dicampur dengan Semen Portland dengan komposisi tertentu. Hal ini dilakukan untuk meningkatkan daya ikat antar butiran keramik. Penelitian ini dilakukan untuk mengetahui penggunaan keramik sebagai dan agregat halus dan filler pada campuran HRS-WC terhadap karakteristik stabilitas, flow, density, VITM, VFWA, VMA, Marshall Quotient dan Immersion Test. Tahap pertama dimulai dari pemeriksaan bahan aspal dan agregat menggunakan spesifikasi Bina Marga. Tahap kedua membuat benda uji untuk mencari kadar aspal optimum dengan filler abu batu dengan kadar aspal 4%, 4,5%, 5%, 5,5%, dan 6%. Tahap ketiga dilakukan pengujian Marshall standar dan Immersion Test pada variasi agregat halus dan filler dengan kadar yaitu 0% keramik, 25% keramik, 50% keramik, 75% keramik dan 100% keramik dengan menggunakan kadar aspal optimum. Dari hasil penelitian dapat disimpulkan bahwa semakin banyak penambahan keramik akan menurunkan nilai stabilitas, Marshall Quotient, VITM dan VMA dan menaikkan nilai flow, density dan VFWA. Keramik dapat digunakan sebagai agregat halus dan filler dalam pembuatan lapis perkerasan HRS dengan variasi kadar 25% keramik.

Effect of brass interlayer on microstructure, mechanical and corrosion behaviour of friction stir welded AA6061-T6 alloy

In this study, friction stir welding (FSW) was performed on AA6061-T6 with and without brass interlayer. The FSW with interlayer was performed for various tool rotational speeds (600–1000 r/min) and at constant travel speed (25 mm/min). The defect-free joint with uniform distribution of brass particles in the stir zone (SZ) and formation of the uniform composite structure was observed at an intermediate optimized tool rotational speed of 800 r/min due to the proper material flow. A strong metallurgical bond between brass particles with aluminium alloy resulted in the formation of Al2Cu and Al4Cu9 strengthening intermetallic compounds (IMCs). The average grain size obtained for the weld with interlayer is smaller than weld without interlayer. The presence of the interlayer enhanced the hardness and the tensile strength compared to the weld without interlayer. This improvement in mechanical properties with interlayer is attributed to the formation and uniform distribution of strengthening IMCs. The corrosion analysis was carried out in 3.5% NaCl solution using immersion test and electrochemical polarization test. The weld with interlayer showed enhanced corrosion resistance than the weld without interlayer which is attributed to the formation of major Al2Cu IMC which has less activation energy for the corrosion process.

Facile Fabrication and Properties of Super-hydrophobic MgAl-LDH Films With Excellent Corrosion Resistance on AZ31 Magnesium Alloy

A super-hydrophobic anti-corrosion film was facilely prepared via in situ growth of layered double hydroxides (LDHs) on the etched AZ31 magnesium alloy and then modification by 1H, 1H, 2H, 2H-perfluorooctyltrimethoxysilane (PFOTMS) in this work. The morphology, structure, composition, surface roughness and water contact angles (WCA), and the anti-corrosion performance of the samples were investigated. The results revealed that the micro/nano hierarchical surface morphology of the films was composed of island structures obtained after chemical etching and MgAl-LDH nanowalls grown in situ. The best hydrophobicity (CA = 163°) was obtained on the MgAl-LDHs with the maximum surface roughness. Additionally, the potentiodynamic polarization, electrochemical impedance spectroscopy, and immersion test indicated that the super-hydrophobic LDH films provided better corrosion resistance to AZ31 magnesium alloy due to the double-protection derived from the LDHs and super-hydrophobic properties. Furthermore, the contact angle could be kept at above 140° after dipped in 3.5 wt% NaCl solution for 6 days.

Investigation on Corrosion Behaviour of Polymeric Coatings on Weathering Steel Under 3.5% NaCl Solution

Weathering steel, a low carbon alloy steel, most widely used in marine transportation and construction fields like bridges, sculptures where corrosion resistance is the main concern. Weathering steel creates an adhering protective coating on its surface in the right environmental conditions. The protective layer which is formed on the surface weathering steel known as patina. It protects the structure from further corrosion to occur. When these weathering steels are continuously exposed to moisture environment its corrosion resistance decreases. So, our investigation deals about the studies of the coatings used on weathering steel to increase its corrosion resistance in marine conditions. The coatings applied on the substrate were poly urea, polyurethane, epoxy and black enamel. Corrosion tests were performed on these coated samples to evaluate their corrosion behaviour in different environments. Corrosion tests that were performed are immersion test, salt spray test and potentio-dynamic test. The profilometry test is investigated and it confirmed the depth of the corrosion on the coatings. Based on the corrosion studies, we conclude that poly urea is the excellent coating followed by polyurethane, black enamel and epoxy.

Focusing on the relationship between the precipitated phases and the pitting corrosion of ZL101A aluminum alloy

The pitting corrosion behavior of ZL101A aluminum alloy in simulated marine environment was investigated for guiding the composition design. The Volta potential of the precipitated phases was mainly characterized via the in-situ SKPFM technique. The obtained results indicated that the precipitated phases of ZL101A were composed of Al-Si phase, Si-Mg-Fe phase and Si-rich/Al-poor phase, accelerating the formation of corrosion pits during immersion test. Both Al-Si phase and Si-Mg-Fe phase accelerated the corrosion process through the self-dissolution and the galvanic effect, respectively, which can be contributed to the high corrosion sensitivity of the two phases. Si-rich/Al-poor phase presented high corrosion resistance, which should be related to the deficiency of impure elements such as Mg and Fe.

COMPARACIÓN ENTRE EL MODELO PROBIT Y EL MODELO DE HILL PARA DETERMINAR LA EFICACIA DE IVERMECTINA SOBRE LARVAS DE Rhipicephalus (Boophilus) microplus (ACARI, IXODIDA: IXODIDAE) MEDIANTE LA TÉCNICA DE INMERSIÓN.

The aim of this study was to propose an alternative statistic treatment for the results obtained by testing the in vitro efficacy of ivermectin (IVM) against R. microplus using the larval immersion test in order to detect the emergence of resistant strains. The statistical analysis of the results obtained by this technique is standardized by the FAO who proposes the use of the Probit model. However there are alternative mathematical models that allow a more precise analysis of experimental data generating more information as nonlinear logistic equation, also called the Hill model. The results of the IVM efficacy against a sensible strain of R. microplus were analysed whit both model. A comparison between the results obtained with PROBIT and Hill model showed that the last one was able to make a more precise fit of the experimental data, generating more information about small IVM concentrations. The C50 (13.58 ppm) obtained with Probit model result smaller than the obtained with the Hill model (14.24 ppm), however the C90, C99 and the discriminant dose (19.31 ppm, 25.74 ppm, 51.48 ppm) obtained with de Hill model were bigger than the obtained with the Probit model (17.50 ppm, 21.98 ppm, 43.96 ppm).

Aggressiveness of Different Ageing Conditions for Three Thick Marine Epoxy Systems

Three different coated steel systems were aged in natural or artificial seawater, in neutral salt spray (NSS), and using alternate immersion tests in order to evaluate the aggressiveness of the different ageing conditions. Commercial epoxy coatings were applied onto steel (S355NL), hot-galvanized steel (HDG), and Zn-Al15 thermal spraying coated steel. The defect-free systems were immersed in artificial seawater at 35 °C for 1085 days and in natural seawater for 1200 days and were characterized by electrochemical impedance spectroscopy (EIS). Panels with artificial defects were immersed for 180 days in artificial seawater and, regarding adhesion, were evaluated according to ISO 16276-2. In parallel, the three coated systems were submitted to cyclic neutral salt spray (NSS) for 1440 h: defect-free panels were regularly evaluated by EIS, while the degree or corrosion was measured onto panels with artificial defect. After NSS, defect-free panels were immersed in artificial seawater at 35 °C for further EIS investigations. Finally, alternate immersion tests were performed for 860 days for the three defect-free coated systems and for 84 days for panels with a defect. The results showed that, for defect-free panels, immersions in natural or artificial seawater and NSS did not allowed us to distinguish the three different systems that show excellent anticorrosion properties. However, during the alternate immersion test, the organic coating system applied onto HDG presented blisters, showing a greater sensitivity to this test than the two other systems. For panels with a defect, NSS allowed to age the coatings more rapidly than monotone conditions, and the coating system applied onto steel presented the highest degree of corrosion. Meanwhile, the coating systems applied onto HDG and the thermal spray metallic coating showed similar behavior. During the alternate immersion test, the three coated systems with a defect showed clearly different behaviors, therefore it was possible to rank the three systems. Finally, it appeared that the alternate immersion test was the most aggressive condition. It was then proposed that a realistic thermal cycling and an artificial defect are needed when performing ageing tests of thick marine organic coating systems in order to properly rank/evaluate the different systems.

An in vivo evaluation of anti-inflammatory, analgesic and anti-pyretic activities of newly synthesized 1, 2, 4 Triazole derivatives

Background In recent years, 1, 2, 4-triazole and its derivatives have been reported to be pharmacologically significant scaffolds. They possess analgesic, anti-tubercular, anti-inflammatory, anti-convulsant, anti-oxidant, anti-fungal, anti-cancer, anxiolytic and anti-depressant activity. This study was designed and conducted to evaluate the potential anti-inflammatory, analgesic and antipyretic activities of Triazole derivatives. Methods Swiss albino (male and female) mice weighing 20-30 g (10-24 weeks female), (5-14 weeks male) and Wister Kyoto rats (male and female) weighing 200-300 g (8-10 weeks old) were used for the present study. Anti-inflammatory activity was checked using Lambda carrageenan (λ) and egg albumin-induced paw edema models. Analgesic via Writhing Reflex induced by acetic acid and formalin, furthermore anti-pyretic activity was assessed by yeast induced pyrexia. Results Both of the test compounds exhibited encouraging anti-inflammatory analgesic and antipyretic results when compared with standard drug ibuprofen. The maximum inhibition of edema for the compound (S)-1-(4-Amino-5-mercapto-4H-1,2,4-triazole-3-yl) ethanol [3] was found to be (91)% as compared to reference drug ibuprofen (82)%, while (S)-1-(6-Phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-yl)ethanol [5e] showed equipotent results to ibuprofen (81)%. The derivatives were also screened for their anti-nociceptive activity by Acetic acid writhing and tail immersion test. Compound 3 showed a significant reduction in wriths (83)% as compared to standard drug ibuprofen 71.5% and [5] showed comparable results to ibuprofen by exhibiting 70% reduction in writh at the same dose as that of standard drug, moreover, there were no signs of toxicity being observed after administration of high doses of test compounds to mice. Conclusions It is evident from the results that compounds 3(compound A) and 5(compound B) are a potential candidate for anti-inflammatory, analgesic and anti-pyretic and the scaffold could be used for further structural modifications. Further studies would help to evaluate their molecular mechanism of action regarding these beneficial activities.