scholarly journals One-step synthesis of polyethyleneimine-coated magnetite nanoparticles and their structural, magnetic and power absorption study

RSC Advances ◽  
2020 ◽  
Vol 10 (68) ◽  
pp. 41807-41815
Author(s):  
Lizbet León Félix ◽  
Marco Antonio Rodriguez Martínez ◽  
David Gregorio Pacheco Salazar ◽  
José Antonio Huamani Coaquira

Magnetic nanoparticles (NPs) are especially interesting for several biomedical applications due to their chemical surface, especially for targeted cancer imaging and therapeutics.

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Christian Chapa Gonzalez ◽  
Carlos A. Martínez Pérez ◽  
Alejandro Martínez Martínez ◽  
Imelda Olivas Armendáriz ◽  
Oscar Zavala Tapia ◽  
...  

Magnetic nanoparticles (MNPs) have great potential in biomedical applications because of their magnetic response offers the possibility to direct them to specific areas and target biological entities. Magnetic separation of biomolecules is one of the most important applications of MNPs because their versatility in detecting cancer biomarkers. However, the effectiveness of this method depends on many factors, including the type of functionalization onto MNPs. Therefore, in this study, magnetite nanoparticles have been developed in order to separate the 5′-nucleotidase enzyme (5eNT). The 5eNT is used as a bio-indicator for diagnosing diseases such as hepatic ischaemia, liver tumor, and hepatotoxic drugs damage. Magnetic nanoparticles were covered in a core/shell type with silica, aminosilane, and a double shell of silica-aminosilane. A ScFv (fragment antibody) and anti-CD73 antibody were attached to the coated nanoparticles in order to separate the enzyme. The magnetic separation of this enzyme with fragment antibody was found to be 28% higher than anti-CD73 antibody and the enzyme adsorption was improved with the double shell due to the increased length of the polymeric chain. Magnetite nanoparticles with a double shell (silica-aminosilane) were also found to be more sensitive than magnetite with a single shell in the detection of biomarkers.


2015 ◽  
Vol 21 (42) ◽  
pp. 6038-6054 ◽  
Author(s):  
Dragoș Gudovan ◽  
Paul Balaure ◽  
Dan Mihăiescu ◽  
Adrian Fudulu ◽  
Bogdan Purcăreanu ◽  
...  

2020 ◽  
Vol 16 (1) ◽  
pp. 1-10
Author(s):  
Tomáš Solný ◽  
Petr Ptáček ◽  
Tomáš Opravil ◽  
Lucie Dlabajová ◽  
Matěj Březina ◽  
...  

Nanoscale ◽  
2021 ◽  
Author(s):  
Frederik Laust Durhuus ◽  
Lau Halkier Wandall ◽  
Mathias Hoeg Boisen ◽  
Mathias Kure ◽  
Marco Beleggia ◽  
...  

Magnetically guided self-assembly of nanoparticles is a promising bottom-up method to fabricate novel materials and superstructures, such as, for example, magnetic nanoparticle clusters for biomedical applications. The existence of assembled...


Materials ◽  
2021 ◽  
Vol 14 (15) ◽  
pp. 4300
Author(s):  
Marta Multigner ◽  
Irene Morales ◽  
Marta Muñoz ◽  
Victoria Bonache ◽  
Fernando Giacomone ◽  
...  

To modulate the properties of degradable implants from outside of the human body represents a major challenge in the field of biomaterials. Polylactic acid is one of the most used polymers in biomedical applications, but it tends to lose its mechanical properties too quickly during degradation. In the present study, a way to reinforce poly-L lactic acid (PLLA) with magnetic nanoparticles (MNPs) that have the capacity to heat under radiofrequency electromagnetic fields (EMF) is proposed. As mechanical and degradation properties are related to the crystallinity of PLLA, the aim of the work was to explore the possibility of modifying the structure of the polymer through the heating of the reinforcing MNPs by EMF within the biological limit range f·H < 5·× 109 Am−1·s−1. Composites were prepared by dispersing MNPs under sonication in a solution of PLLA. The heat released by the MNPs was monitored by an infrared camera and changes in the polymer were analyzed with differential scanning calorimetry and nanoindentation techniques. The crystallinity, hardness, and elastic modulus of nanocomposites increase with EMF treatment.


Author(s):  
Shane Harstad ◽  
Shivakumar Hunagund ◽  
Zoe Boekelheide ◽  
Zainab A. Hussein ◽  
Ahmed A. El-Gendy ◽  
...  

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