scholarly journals Dielectrophoretic separation of platelet cells in a microfluidic channel and optimization with fuzzy logic

RSC Advances ◽  
2020 ◽  
Vol 10 (56) ◽  
pp. 33731-33738
Author(s):  
Ishak Ertugrul ◽  
Osman Ulkir
Keyword(s):  
Fuzzy Logic ◽  
Red Blood Cells ◽  
Microfluidic Chip ◽  
Blood Cells ◽  
Microfluidic Channel ◽  
Optimization Techniques

It is the aim to develop optimization techniques to separate platelets from Red Blood Cells (RBCs) after designing and analyzing a microfluidic chip in this study.

scholarly journals Correction: Cross-sectional focusing of red blood cells in a constricted microfluidic channel

Soft Matter ◽  
2020 ◽  
Vol 16 (7) ◽  
pp. 1941-1941
Author(s):  
Asena Abay ◽  
Steffen M. Recktenwald ◽  
Thomas John ◽  
Lars Kaestner ◽  
Christian Wagner
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Soft Matter ◽  
Microfluidic Channel ◽  
Cross Sectional

Correction for ‘Cross-sectional focusing of red blood cells in a constricted microfluidic channel’ by Asena Abay et al., Soft Matter, 2020, 16, 534–543.

Deformability measurement of red blood cells using a microfluidic channel array and an air cavity in a driving syringe with high throughput and precise detection of subpopulations

The Analyst ◽  
2016 ◽  
Vol 141 (1) ◽  
pp. 319-330 ◽  
Author(s):  
Yang Jun Kang ◽  
Young-Ran Ha ◽  
Sang-Joon Lee
Keyword(s):  
Red Blood Cells ◽  
High Throughput ◽  
Blood Cells ◽  
Microfluidic Channel ◽  
New Method ◽  
Air Cavity ◽  
Blood Samples ◽  
Hematological Disorders

We propose a new method to measure deformability of blood samples containing hematological disorders with high throughput and precise detection of subpopulations.

Frequency-enhanced transferrin receptor antibody-labelled microfluidic chip (FETAL-Chip) enables efficient enrichment of circulating nucleated red blood cells for non-invasive prenatal diagnosis

Lab on a Chip ◽  
2018 ◽  
Vol 18 (18) ◽  
pp. 2749-2756 ◽  
Author(s):  
Huimin Zhang ◽  
Yuanyuan Yang ◽  
Xingrui Li ◽  
Yuanzhi Shi ◽  
Bin Hu ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Red Blood Cells ◽  
Microfluidic Chip ◽  
Transferrin Receptor ◽  
Blood Cells ◽  
Receptor Antibody ◽  
Non Invasive ◽  
Nucleated Red Blood Cells

We proposed a FETAL-Chip for efficient enrichment of cNRBCs, which offers great potential for NIPD.

scholarly journals Cross-sectional focusing of red blood cells in a constricted microfluidic channel

Soft Matter ◽  
2020 ◽  
Vol 16 (2) ◽  
pp. 534-543 ◽  
Author(s):  
Asena Abay ◽  
Steffen M. Recktenwald ◽  
Thomas John ◽  
Lars Kaestner ◽  
Christian Wagner
Keyword(s):  
Density Distribution ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Microfluidic Channel ◽  
Microfluidic Devices ◽  
Cross Sectional ◽  
Strong Change

The density distribution of red blood cells in microfluidic devices reveals a strong change passing an abrupt constriction.

scholarly journals A biomimetic microfluidic chip to study the circulation and mechanical retention of red blood cells in the spleen

2015 ◽  
Vol 90 (4) ◽  
pp. 339-345 ◽  
Author(s):  
Julien Picot ◽  
Papa Alioune Ndour ◽  
Sophie D. Lefevre ◽  
Wassim El Nemer ◽  
Harvey Tawfik ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Microfluidic Chip ◽  
Blood Cells

scholarly journals Design and Simulation of a Point-of-Care Microfluidic Device for Acoustic Blood Cell Separation

2020 ◽  
Vol 2 (1) ◽  
pp. 76
Author(s):  
Fatemeh Sharifi ◽  
Armin Sedighi ◽  
Mubashar Rehman
Keyword(s):  
Blood Cell ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Cell Separation ◽  
Numerical Study ◽  
Point Of Care ◽  
Surface Acoustic Waves ◽  
White Blood Cells ◽  
Microfluidic Channel ◽  
Diagnostic Process

Hematology tests, considered as an initial step in the patient diagnostic process, require laboratory equipment and technicians which is a time- and labor-consuming procedure. Such facilities may be available in a few central laboratories in under-resourced countries. The growing need for low cost and rapid diagnostic tests contributes to point-of-care (POC) medical diagnostic devices providing convenient and rapid test tools particularly in areas with limited medical resources. In the present study, a comprehensive numerical simulation of a POC blood cell separation device (POC-BCS) has been modeled using a finite element method. Tag-less separation of blood cells, i.e., platelets, red blood cells, and white blood cells, was carried out using standing surface acoustic waves (SSAWs) generated by interdigital transducers (IDTs) located at lateral sides of the microfluidic channel. Blood sample intake along with sheath flow was introduced via two symmetrical tilted angle inlets and a middle inlet, respectively. Superposition of acoustic radiation force applied by SSAWs accompanied by drag force caused by medium flow drove the blood cells toward different path lines correlated to their size. White blood cells were sorted out in the middle outlet and red blood cells and platelets were sorted out through the separate locations of the side outlets. Each cell was then guided to their respected visualization chamber for further image processing analysis. The results of the presented numerical study would be very promising in designing and optimizing the POC blood testing device.

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