Synthesis of polysubstituted quinolines through promoter-regulated selective annulation and C–C bond cleavage from 2-styrylanilines and β-keto esters

2020 ◽  
Vol 7 (21) ◽  
pp. 3368-3373 ◽  
Author(s):  
Hui Xu ◽  
Fei Yu ◽  
Ronglu Huang ◽  
Mingyue Weng ◽  
Hong Chen ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Keto Esters ◽  
Chemoselective Synthesis

I2 and Mn(OAc)3 regulated annulation of 2-styrylanilines and β-keto esters is accomplished for chemoselective synthesis of 2-alkylquinolines and quinoline-2-carboxylates.

I2/TBHP-Promoted Approach to α-Keto Esters from Trifluoromethyl β-Diketones and Alcohols via C–C Bond Cleavage

Synlett ◽  
2017 ◽  
Vol 28 (15) ◽  
pp. 2018-2023 ◽  
Author(s):  
Xiang Fang ◽  
Xueyan Yang ◽  
Tongle Shao ◽  
Jun Zhou ◽  
Chen Jin ◽  
...  
Keyword(s):  
Oxidative Coupling ◽  
Bond Cleavage ◽  
Bond Formation ◽  
Coupling Reaction ◽  
Mechanistic Studies ◽  
Metal Free ◽  
Oxidation Pathway ◽  
Keto Esters ◽  
Oxidative Coupling Reaction

A metal-free oxidative coupling reaction of trifluoromethyl β-diketones with alcohols for the synthesis of α-keto esters in good to excellent yields has been developed. Preliminary mechanistic studies suggest that an I2/TBHP promoted sequential iodination, C–C bond cleavage, C–O bond formation and oxidation pathway is involved in this reaction.

Chemoselective Synthesis of Aryl Ketones from Amides and Grignard Reagents via C(O)–N Bond Cleavage under Catalyst-Free Conditions

2019 ◽  
Vol 84 (18) ◽  
pp. 11823-11838 ◽  
Author(s):  
Popuri Sureshbabu ◽  
Sadaf Azeez ◽  
Nalluchamy Muniyappan ◽  
Shahulhameed Sabiah ◽  
Jeyakumar Kandasamy
Keyword(s):  
Bond Cleavage ◽  
Grignard Reagents ◽  
Catalyst Free ◽  
Chemoselective Synthesis ◽  
Aryl Ketones

CH Functionalization/CO Bond Cleavage of Benzyl Silyl Ethers with Ynamides for the Chemoselective Synthesis of Skeletally Diverse Compounds

2016 ◽  
Vol 358 (3) ◽  
pp. 480-485 ◽  
Author(s):  
Ling Chen ◽  
Lian Yu ◽  
Yuan Deng ◽  
Zhan-Jiang Zheng ◽  
Zheng Xu ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Silyl Ethers ◽  
Chemoselective Synthesis

Scalable and Chemoselective Synthesis of γ-Keto Esters and Acids via Pd-Catalyzed Carbonylation of Cyclic β-Chloro Enones

2018 ◽  
Vol 38 (1) ◽  
pp. 85-96 ◽  
Author(s):  
Justin M. Kaplan ◽  
Damian P. Hruszkewycz ◽  
Iulia I. Strambeanu ◽  
Christopher J. Nunn ◽  
Kelsey F. VanGelder ◽  
...  
Keyword(s):  
Keto Esters ◽  
Chemoselective Synthesis

Chemoselective Synthesis of Pyrazole Derivatives via b-Enamino Keto Esters

Heterocycles ◽  
2000 ◽  
Vol 53 (12) ◽  
pp. 2775 ◽  
Author(s):  
Augusto C. Veronese ◽  
Monica Manferdini ◽  
Carlo F. Morelli
Keyword(s):  
Pyrazole Derivatives ◽  
Keto Esters ◽  
Chemoselective Synthesis

Amidic C–N bond cleavage of isatin: chemoselective synthesis of pyrrolo[2,3,4-kl]acridin-1-ones using Ag NPs decorated rGO composite as an efficient and recoverable catalyst under microwave irradiation

RSC Advances ◽  
2015 ◽  
Vol 5 (111) ◽  
pp. 91888-91902 ◽  
Author(s):  
Anshu Dandia ◽  
Amit Sharma ◽  
Vijay Parewa ◽  
Begraj Kumawat ◽  
Kuldeep S. Rathore ◽  
...  
Keyword(s):  
Microwave Irradiation ◽  
Ring Opening ◽  
Bond Cleavage ◽  
Selective Synthesis ◽  
Ag Nps ◽  
Recoverable Catalyst ◽  
Chemoselective Synthesis ◽  
Facile Route

A facile route for the chemo-selective synthesis of pyrrolo[2,3,4-kl]acridin-1-ones via ring-opening or amidic C–N bond cleavage of isatin under microwave irradiation using Ag NPs/rGO composite as an effective and robust catalyst has been described.

ChemInform Abstract: Chemoselective Synthesis of Pyrazole Derivatives via β-Enamino Keto Esters.

ChemInform ◽  
2001 ◽  
Vol 32 (12) ◽  
pp. no-no
Author(s):  
Monica Manferdini ◽  
Carlo F. Morelli ◽  
Augusto C. Veronese
Keyword(s):  
Pyrazole Derivatives ◽  
Keto Esters ◽  
Chemoselective Synthesis
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