ChemInform Abstract: C-H Functionalization/C-O Bond Cleavage of Benzyl Silyl Ethers with Ynamides for the Chemoselective Synthesis of Skeletally Diverse Compounds.

ChemInform ◽  
2016 ◽  
Vol 47 (24) ◽  
Author(s):  
Ling Chen ◽  
Lian Yu ◽  
Yuan Deng ◽  
Zhan-Jiang Zheng ◽  
Zheng Xu ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Silyl Ethers ◽  
Chemoselective Synthesis

CH Functionalization/CO Bond Cleavage of Benzyl Silyl Ethers with Ynamides for the Chemoselective Synthesis of Skeletally Diverse Compounds

2016 ◽  
Vol 358 (3) ◽  
pp. 480-485 ◽  
Author(s):  
Ling Chen ◽  
Lian Yu ◽  
Yuan Deng ◽  
Zhan-Jiang Zheng ◽  
Zheng Xu ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Silyl Ethers ◽  
Chemoselective Synthesis

Chemoselective Synthesis of Aryl Ketones from Amides and Grignard Reagents via C(O)–N Bond Cleavage under Catalyst-Free Conditions

2019 ◽  
Vol 84 (18) ◽  
pp. 11823-11838 ◽  
Author(s):  
Popuri Sureshbabu ◽  
Sadaf Azeez ◽  
Nalluchamy Muniyappan ◽  
Shahulhameed Sabiah ◽  
Jeyakumar Kandasamy
Keyword(s):  
Bond Cleavage ◽  
Grignard Reagents ◽  
Catalyst Free ◽  
Chemoselective Synthesis ◽  
Aryl Ketones

Amidic C–N bond cleavage of isatin: chemoselective synthesis of pyrrolo[2,3,4-kl]acridin-1-ones using Ag NPs decorated rGO composite as an efficient and recoverable catalyst under microwave irradiation

RSC Advances ◽  
2015 ◽  
Vol 5 (111) ◽  
pp. 91888-91902 ◽  
Author(s):  
Anshu Dandia ◽  
Amit Sharma ◽  
Vijay Parewa ◽  
Begraj Kumawat ◽  
Kuldeep S. Rathore ◽  
...  
Keyword(s):  
Microwave Irradiation ◽  
Ring Opening ◽  
Bond Cleavage ◽  
Selective Synthesis ◽  
Ag Nps ◽  
Recoverable Catalyst ◽  
Chemoselective Synthesis ◽  
Facile Route

A facile route for the chemo-selective synthesis of pyrrolo[2,3,4-kl]acridin-1-ones via ring-opening or amidic C–N bond cleavage of isatin under microwave irradiation using Ag NPs/rGO composite as an effective and robust catalyst has been described.

Synthesis of polysubstituted quinolines through promoter-regulated selective annulation and C–C bond cleavage from 2-styrylanilines and β-keto esters

2020 ◽  
Vol 7 (21) ◽  
pp. 3368-3373 ◽  
Author(s):  
Hui Xu ◽  
Fei Yu ◽  
Ronglu Huang ◽  
Mingyue Weng ◽  
Hong Chen ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Keto Esters ◽  
Chemoselective Synthesis

I2 and Mn(OAc)3 regulated annulation of 2-styrylanilines and β-keto esters is accomplished for chemoselective synthesis of 2-alkylquinolines and quinoline-2-carboxylates.

scholarly journals Tactics for probing aryne reactivity: mechanistic studies of silicon–oxygen bond cleavage during the trapping of (HDDA-generated) benzynes by silyl ethers

2014 ◽  
Vol 5 (2) ◽  
pp. 545-550 ◽  
Author(s):  
Thomas R. Hoye ◽  
Beeraiah Baire ◽  
Tao Wang
Keyword(s):  
Bond Cleavage ◽  
Mechanistic Studies ◽  
Silyl Ethers ◽  
Oxygen Bond ◽  
Silicon Oxygen ◽  
Clock Reaction

Mechanistic features of the trapping reaction of an HDDA-generated aryne by pendant silyl ethers were probed using, e.g., an intramolecular clock reaction (cf. k2).

SuFExable Polymers with Helical Structures Derived from Thionyl Tetrafluoride (SOF4)

2019 ◽  
Author(s):  
Suhua Li ◽  
Gencheng Li ◽  
Bing Gao ◽  
Sidharam P. Pujari ◽  
Xiaoyan Chen ◽  
...  
Keyword(s):  
Functional Polymers ◽  
Polymer Chains ◽  
New Materials ◽  
Helical Structures ◽  
Polymer Backbone ◽  
Silyl Ethers ◽  
Helical Polymer ◽  
Key Characteristics ◽  
Post Modification ◽  
Individual Polymer

The first SuFEx click chemistry synthesis of SOF<sub>4</sub>-derived copolymers based upon the polymerization of bis(iminosulfur oxydifluorides) and bis(aryl silyl ethers) is described. This novel class of SuFEx polymer presents two key characteristics: First, the newly created [-N=S(=O)F-O-] polymer backbone linkages are themselves SuFExable and primed to undergo further high-yielding and precise SuFEx-based post-modification with phenols or amines to yield branched functional polymers. Second, studies of individual polymer chains of several of these new materials indicate the presence of helical polymer structures, which itself suggests a preferential approach of new monomers onto the growing polymer chain upon the formation of the stereogenic linking moiety.

Metal-Metal Cooperative Bond Activation by Heterobimetallic Alkyl, Aryl, and Acetylide PtII/CuI Complexes

2020 ◽  
Author(s):  
Shubham Deolka ◽  
Orestes Rivada Wheelaghan ◽  
Sandra Aristizábal ◽  
Robert Fayzullin ◽  
Shrinwantu Pal ◽  
...  
Keyword(s):  
Alkyl Group ◽  
Bond Activation ◽  
Bond Cleavage ◽  
Terminal Alkyne ◽  
Alkyl Aryl ◽  
Metal Metal ◽  
The Stability ◽  
Selective Formation ◽  
Organoplatinum Compounds

We report selective formation of heterobimetallic PtII/CuI complexes that demonstrate how facile bond activation processes can be achieved by altering reactivity of common organoplatinum compounds through their interaction with another metal center. The interaction of the Cu center with Pt center and with a Pt-bound alkyl group increases the stability of PtMe2 towards undesired rollover cyclometalation. The presence of the CuI center also enables facile transmetalation from electron-deficient tetraarylborate [B(ArF)4]- anion and mild C-H bond cleavage of a terminal alkyne, which was not observed in the absence of an electrophilic Cu center. The DFT study indicates that the role of Cu center acts as a binding site for alkyne substrate, while activating its terminal C-H bond.

Room Temperature Alkali Metal Reduction of Carbon Dioxide

2020 ◽  
Author(s):  
Lucas A. Freeman ◽  
Akachukwu D. Obi ◽  
Haleigh R. Machost ◽  
Andrew Molino ◽  
Asa W. Nichols ◽  
...  
Keyword(s):  
Alkali Metal ◽  
Alkali Metals ◽  
Room Temperature ◽  
Chemical Reduction ◽  
Bond Cleavage ◽  
Open Shell ◽  
Metal Reduction ◽  
One Pot ◽  
Earth Abundant ◽  
Electron Reduction

The reduction of the relatively inert carbon–oxygen bonds of CO<sub>2</sub> to access useful CO<sub>2</sub>-derived organic products is one of the most important fundamental challenges in synthetic chemistry. Facilitating this bond-cleavage using earth-abundant, non-toxic main group elements (MGEs) is especially arduous because of the difficulty in achieving strong inner-sphere interactions between CO<sub>2</sub> and the MGE. Herein we report the first successful chemical reduction of CO<sub>2</sub> at room temperature by alkali metals, promoted by a cyclic(alkyl)(amino) carbene (CAAC). One-electron reduction of CAAC-CO<sub>2</sub> adduct (<b>1</b>) with lithium, sodium or potassium metal yields stable monoanionic radicals clusters [M(CAAC–CO<sub>2</sub>)]<sub>n</sub>(M = Li, Na, K, <b> 2</b>-<b>4</b>) and two-electron alkali metal reduction affords open-shell, dianionic clusters of the general formula [M<sub>2</sub>(CAAC–CO<sub>2</sub>)]<sub>n </sub>(<b>5</b>-<b>8</b>). It is notable that these crystalline clusters of reduced CO<sub>2</sub> may also be isolated via the “one-pot” reaction of free CO<sub>2</sub> with free CAAC followed by the addition of alkali metals – a reductive process which does not occur in the absence of carbene. Each of the products <b>2</b>-<b>8</b> were investigated using a combination of experimental and theoretical methods.<br>

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