scholarly journals Tuneable manganese oxide nanoparticle based theranostic agent for potential diagnosis and drug delivery

2021 ◽  
Author(s):  
Kingsley Won-ching Poon ◽  
Zufu Lu ◽  
Yves De Deene ◽  
Yogambha Ramaswamy ◽  
Hala Zreiqat ◽  
...  
Keyword(s):  
Manganese Oxide ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Preclinical Research ◽  
Manganese Oxide Nanoparticles ◽  
Mri Contrast ◽  
Theranostic Agent ◽  
Oxide Nanoparticle ◽  
Magnetic Resonance Imaging Mri

Among various magnetic nanoparticles, manganese oxide nanoparticles are considered as an established T1 magnetic resonance imaging (MRI) contrast agents for preclinical research. The implications of their degradation property and use...

Biocompatible dextran-coated gadolinium-doped cerium oxide nanoparticles as MRI contrast agents with high T1 relaxivity and selective cytotoxicity to cancer cells

2021 ◽  
Author(s):  
Anton Popov ◽  
Maxim Artemovich Abakumov ◽  
Irina Savintseva ◽  
Artem Ermakov ◽  
Nelly Popova ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Selective Cytotoxicity ◽  
Magnetic Resonance Imaging Mri

Gd-based complexes are widely used as magnetic resonance imaging (MRI) contrast agents. The safety of previously approved contrast agents is questionable and is being re-assessed. The main causes of concern...

Stem cell tracking using effective self-assembled peptide-modified superparamagnetic nanoparticles

Nanoscale ◽  
2018 ◽  
Vol 10 (34) ◽  
pp. 15967-15979 ◽  
Author(s):  
Lei Gu ◽  
Xue Li ◽  
Jing Jiang ◽  
Gang Guo ◽  
Haoxing Wu ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Tracking ◽  
Superparamagnetic Iron Oxide ◽  
Mri Contrast Agents ◽  
Superparamagnetic Nanoparticles ◽  
Cell Labeling ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Magnetic Resonance Imaging Mri

Peptide modified superparamagnetic iron oxide nanoparticles (SPIONs) have been developed as excellent magnetic resonance imaging (MRI) contrast agents for stem cell labeling and tracking due to their biocompatibility.

scholarly journals L-DOPA-Coated Manganese Oxide Nanoparticles as Dual MRI Contrast Agents and Drug-Delivery Vehicles

Small ◽  
2015 ◽  
Vol 12 (3) ◽  
pp. 301-306 ◽  
Author(s):  
Birgitte Hjelmeland McDonagh ◽  
Gurvinder Singh ◽  
Sjoerd Hak ◽  
Sulalit Bandyopadhyay ◽  
Ingrid Lovise Augestad ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Contrast Agents ◽  
Manganese Oxide ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Manganese Oxide Nanoparticles ◽  
Mri Contrast ◽  
Drug Delivery Vehicles ◽  
Delivery Vehicles

scholarly journals Highly water-dispersible calcium lignosulfonate-capped MnO nanoparticles as a T1 MRI contrast agent with exceptional colloidal stability, low toxicity and remarkable relaxivity

RSC Advances ◽  
2019 ◽  
Vol 9 (69) ◽  
pp. 40498-40506
Author(s):  
Mahdi Arian ◽  
Ali Zamanian ◽  
Salman Taheri
Keyword(s):  
Colloidal Stability ◽  
Mri Contrast Agent ◽  
Oxide Nanoparticles ◽  
Potential Candidate ◽  
Resonance Imaging ◽  
Manganese Oxide Nanoparticles ◽  
Mri Contrast ◽  
Water Dispersible ◽  
Low Toxicity ◽  
Magnetic Resonance Imaging Mri

A simple and efficient method to synthesize highly water-dispersible calcium lignosulfonate-coated manganese oxide nanoparticles as a potential candidate for the current magnetic resonance imaging (MRI) T1 contrast agents was reported.

Iron oxide nanoparticles for targeted imaging of liver tumors with ultralow hepatotoxicity

2018 ◽  
Vol 6 (40) ◽  
pp. 6413-6423 ◽  
Author(s):  
Juanjuan Li ◽  
Ruitao Cha ◽  
Yulong Zhang ◽  
Hongbo Guo ◽  
Keying Long ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Liver Tumors ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Targeted Imaging ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Magnetic Resonance Imaging Mri

Even though iron oxide (Fe3O4) nanoparticles are promising materials for magnetic resonance imaging (MRI) contrast agents, their biocompatibility and targeting efficacy still need to be improved.

Silica-coated super-paramagnetic iron oxide nanoparticles (SPIONPs): a new type contrast agent of T1 magnetic resonance imaging (MRI)

2015 ◽  
Vol 3 (26) ◽  
pp. 5172-5181 ◽  
Author(s):  
M. Zubair Iqbal ◽  
Xuehua Ma ◽  
Tianxiang Chen ◽  
Ling'e Zhang ◽  
Wenzhi Ren ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
New Type ◽  
Magnetic Resonance Imaging Mri

Silica-coated-SPIONPs-T1 enhanced MRI contrast agents.

scholarly journals Manganese Oxide Nanoparticles As MRI Contrast Agents In Tumor Multimodal Imaging And Therapy

2019 ◽  
Vol Volume 14 ◽  
pp. 8321-8344 ◽  
Author(s):  
Xiaoxia Cai ◽  
Qingxia Zhu ◽  
Yun Zeng ◽  
Qi Zeng ◽  
Xueli Chen ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Manganese Oxide ◽  
Multimodal Imaging ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Manganese Oxide Nanoparticles ◽  
Mri Contrast

EDTMP ligand-enhanced water interaction endowing iron oxide nanoparticles with dual-modal MRI contrast ability

2021 ◽  
Author(s):  
Lili Hao ◽  
Peng Wang ◽  
Zhenxu Wu ◽  
Zongliang Wang ◽  
Yu Wang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Iron Oxide Nanoparticles ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Water Interaction ◽  
Magnetic Resonance Imaging Mri

Single-modal magnetic resonance imaging (MRI) contrast agents sometimes causes signal confusion in clinical diagnosis. Utilizing ligands to endow iron oxide nanoparticles (IO NPs) with excellent dual-modal MRI contrast efficiency might...

scholarly journals Magnetism for Drug Delivery, MRI and Hyperthermia Applications: a Review

2020 ◽  
Vol 11 (2) ◽  
pp. 8654-8668
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Magnetic Resonance ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Magnetic Resonance Imaging Mri

Superparamagnetic nanoparticles contain unique magnetic properties that differ from the bulk materials and are able to function at a cellular level due to their size, shape, and surface characteristics. These features make them attractive candidates for drug delivery systems, thermal mediators in hyperthermia, and magnetic resonance imaging (MRI) contrast agents. This review provides an up-to-date overview of the application of iron oxide nanoparticles in cancer diagnosis, drug delivery, treatment, and safety concerns related to these materials are considered, as well. Furthermore, the general principles and challenges of the magnetic behavior of nanoparticles in the field of oncology are also discussed. Firstly, the basic requirements for magnetic nanoparticles for biomedical applications are outlined. The close link between structure, shape, size, and magnetic characterization are described, which is considered essential for non-invasive imaging modality, innovative magnetic-driven nanocarriers, and treatment based on the overheating. In conclusion, investigation of the toxicity profile of novel nanoparticles is provided, as well. In the current review, the attention is focused on the role of magnetic nanoparticles, especially iron oxide nanoparticles in some bioapplications such as magnetic resonance imaging (MRI) contrast agents, targeted drug delivery, and magnetic hyperthermia systems.

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