EDTMP ligand-enhanced water interaction endowing iron oxide nanoparticles with dual-modal MRI contrast ability

2021 ◽  
Author(s):  
Lili Hao ◽  
Peng Wang ◽  
Zhenxu Wu ◽  
Zongliang Wang ◽  
Yu Wang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Iron Oxide Nanoparticles ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Water Interaction ◽  
Magnetic Resonance Imaging Mri

Single-modal magnetic resonance imaging (MRI) contrast agents sometimes causes signal confusion in clinical diagnosis. Utilizing ligands to endow iron oxide nanoparticles (IO NPs) with excellent dual-modal MRI contrast efficiency might...

Iron oxide nanoparticles for targeted imaging of liver tumors with ultralow hepatotoxicity

2018 ◽  
Vol 6 (40) ◽  
pp. 6413-6423 ◽  
Author(s):  
Juanjuan Li ◽  
Ruitao Cha ◽  
Yulong Zhang ◽  
Hongbo Guo ◽  
Keying Long ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Liver Tumors ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Targeted Imaging ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Magnetic Resonance Imaging Mri

Even though iron oxide (Fe3O4) nanoparticles are promising materials for magnetic resonance imaging (MRI) contrast agents, their biocompatibility and targeting efficacy still need to be improved.

Silica-coated super-paramagnetic iron oxide nanoparticles (SPIONPs): a new type contrast agent of T1 magnetic resonance imaging (MRI)

2015 ◽  
Vol 3 (26) ◽  
pp. 5172-5181 ◽  
Author(s):  
M. Zubair Iqbal ◽  
Xuehua Ma ◽  
Tianxiang Chen ◽  
Ling'e Zhang ◽  
Wenzhi Ren ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
New Type ◽  
Magnetic Resonance Imaging Mri

Silica-coated-SPIONPs-T1 enhanced MRI contrast agents.

scholarly journals Magnetism for Drug Delivery, MRI and Hyperthermia Applications: a Review

2020 ◽  
Vol 11 (2) ◽  
pp. 8654-8668
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Magnetic Resonance ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Magnetic Resonance Imaging Mri

Superparamagnetic nanoparticles contain unique magnetic properties that differ from the bulk materials and are able to function at a cellular level due to their size, shape, and surface characteristics. These features make them attractive candidates for drug delivery systems, thermal mediators in hyperthermia, and magnetic resonance imaging (MRI) contrast agents. This review provides an up-to-date overview of the application of iron oxide nanoparticles in cancer diagnosis, drug delivery, treatment, and safety concerns related to these materials are considered, as well. Furthermore, the general principles and challenges of the magnetic behavior of nanoparticles in the field of oncology are also discussed. Firstly, the basic requirements for magnetic nanoparticles for biomedical applications are outlined. The close link between structure, shape, size, and magnetic characterization are described, which is considered essential for non-invasive imaging modality, innovative magnetic-driven nanocarriers, and treatment based on the overheating. In conclusion, investigation of the toxicity profile of novel nanoparticles is provided, as well. In the current review, the attention is focused on the role of magnetic nanoparticles, especially iron oxide nanoparticles in some bioapplications such as magnetic resonance imaging (MRI) contrast agents, targeted drug delivery, and magnetic hyperthermia systems.

Biocompatible dextran-coated gadolinium-doped cerium oxide nanoparticles as MRI contrast agents with high T1 relaxivity and selective cytotoxicity to cancer cells

2021 ◽  
Author(s):  
Anton Popov ◽  
Maxim Artemovich Abakumov ◽  
Irina Savintseva ◽  
Artem Ermakov ◽  
Nelly Popova ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Selective Cytotoxicity ◽  
Magnetic Resonance Imaging Mri

Gd-based complexes are widely used as magnetic resonance imaging (MRI) contrast agents. The safety of previously approved contrast agents is questionable and is being re-assessed. The main causes of concern...

Applications of Iron Oxide Nanoparticles in Magnetic Resonance Imaging (MRI)

2020 ◽  
Vol 10 ◽  
Author(s):  
Pratishtha Kushwaha ◽  
Pratima Chauhan
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Iron Oxide Nanoparticles ◽  
The Body ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Low Contrast ◽  
Magnetic Resonance Imaging Mri ◽  
Surface Covering

Abstract: Iron oxide nanoparticles by the help of legitimate surface science have been broadly utilized tentatively in many living organism applications, for example magnetic resonance imaging (MRI), drug delivery, Repair of tissue, immunobiology, hyperthermia, detoxification of natural liquids, differentiate improvement between low contrast and high contrast tissues, and in cell partition and so on. What's more, these applications need exceptional nontoxic and biocompatible surface covering of the attractive particles to permit a targetable conveyance with molecular restriction in a particular territory. The general size of the colloid can be estimated ordinarily of surface covering and their resulting spatial course of action adjacent to the nanoparticles, it additionally assumes a critical job in bio-kinetics and bio-distribution of nanoparticles in the body. The kinds of surface coatings, for this sort of nanoparticles rely upon the kind of application and ought to be picked by remembering a specific application, regardless of whether it is gone for aggravation reaction or anti-cancer agents. In this paper, we examine the manufactured science, liquid adjustment and surface change of iron oxide nanoparticles, just as their utilization for biomedical applications

Phosphocholine-decorated superparamagnetic iron oxide nanoparticles: defining the structure and probing in vivo applications

Nanoscale ◽  
2016 ◽  
Vol 8 (19) ◽  
pp. 10078-10086 ◽  
Author(s):  
Alessandra Luchini ◽  
Carlo Irace ◽  
Rita Santamaria ◽  
Daniela Montesarchio ◽  
Richard K. Heenan ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri

Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are performing contrast agents for Magnetic Resonance Imaging (MRI).

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