scholarly journals Ag and Mn-doped mesoporous bioactive glass nanoparticles incorporated into the chitosan/gelatin coatings deposited on PEEK/bioactive glass layers for favorable osteogenic differentiation and antibacterial activity

2020 ◽  
Vol 1 (5) ◽  
pp. 1273-1284 ◽  
Author(s):  
Aneeqa Nawaz ◽  
Shaher Bano ◽  
Muhammad Yasir ◽  
Abdul Wadood ◽  
Muhammad Atiq Ur Rehman

Multifunctional bioactive and antibacterial coatings for orthopedic applications.

Author(s):  
Jiangfeng Li ◽  
Junying Li ◽  
Yuhao Wei ◽  
Na Xu ◽  
Jingtao Li ◽  
...  

Vanadium is an important trace element in bone to involve in bone metabolism, bone formation, and bone growth, but roles of various vanadium ions, especially pentavalent vanadium, in bone tissue...


2020 ◽  
Vol 37 (7) ◽  
pp. 2000054 ◽  
Author(s):  
Kai Zheng ◽  
Yuqian Fan ◽  
Elisa Torre ◽  
Preethi Balasubramanian ◽  
Nicola Taccardi ◽  
...  

Author(s):  
Youwen Yang ◽  
changfu lu ◽  
mingli yang ◽  
dongsheng wang ◽  
Shuping Peng ◽  
...  

Biodegradable magnesium (Mg) scaffold as bone repair material is desired to own antibacterial function to reduce the risk of bacterial infection. The alloying with antibacterial metal element such as copper...


Materials ◽  
2021 ◽  
Vol 14 (8) ◽  
pp. 1864
Author(s):  
Fabian Westhauser ◽  
Simon Decker ◽  
Qaisar Nawaz ◽  
Felix Rehder ◽  
Sebastian Wilkesmann ◽  
...  

Mesoporous bioactive glass nanoparticles (MBGNs) have gained relevance in bone tissue engineering, especially since they can be used as vectors for therapeutically active ions like zinc (Zn) or copper (Cu). In this study, the osteogenic properties of the ionic dissolution products (IDPs) of undoped MBGNs (composition in mol%: 70 SiO2, 30 CaO) and MBGNs doped with 5 mol% of either Zn (5Zn-MBGNs) or Cu (5Cu-MBGNs; compositions in mol%: 70 SiO2, 25 CaO, 5 ZnO/CuO) on human bone marrow-derived mesenchymal stromal cells were evaluated. Extracellular matrix (ECM) formation and calcification were assessed, as well as the IDPs’ influence on viability, cellular osteogenic differentiation and the expression of genes encoding for relevant members of the ECM. The IDPs of undoped MBGNs and 5Zn-MBGNs had a comparable influence on cell viability, while it was enhanced by IDPs of 5Cu-MBGNs compared to the other MBGNs. IDPs of 5Cu-MBGNs had slightly positive effects on ECM formation and calcification. 5Zn-MBGNs provided the most favorable pro-osteogenic properties since they increased not only cellular osteogenic differentiation and ECM-related gene expression but also ECM formation and calcification significantly. Future studies should analyze other relevant properties of MBGNs, such as their impact on angiogenesis.


RSC Advances ◽  
2020 ◽  
Vol 10 (73) ◽  
pp. 44835-44840
Author(s):  
Xiang Qin ◽  
Rong Cao ◽  
Jingjing Zheng ◽  
Guojun Shi ◽  
Lijun Ji ◽  
...  

A new strategy for preparing mesoporous metal-doped bioactive glass fibers.


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