O-Acrylamidomethyl-2-hydroxypropyltrimethyl ammonium chloride chitosan and silk modified mesoporous bioactive glass scaffolds with excellent mechanical properties, bioactivity and long-lasting antibacterial activity

RSC Advances ◽  
2016 ◽  
Vol 6 (71) ◽  
pp. 66938-66948 ◽  
Author(s):  
Panyu Zhou ◽  
Yan Xia ◽  
Liqiang Jiang ◽  
Yuntong Zhang ◽  
Chao Qiu ◽  
...  
2020 ◽  
Vol 1 (5) ◽  
pp. 1273-1284 ◽  
Author(s):  
Aneeqa Nawaz ◽  
Shaher Bano ◽  
Muhammad Yasir ◽  
Abdul Wadood ◽  
Muhammad Atiq Ur Rehman

Multifunctional bioactive and antibacterial coatings for orthopedic applications.


Author(s):  
Youwen Yang ◽  
changfu lu ◽  
mingli yang ◽  
dongsheng wang ◽  
Shuping Peng ◽  
...  

Biodegradable magnesium (Mg) scaffold as bone repair material is desired to own antibacterial function to reduce the risk of bacterial infection. The alloying with antibacterial metal element such as copper...


Nanomaterials ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1282 ◽  
Author(s):  
Se Young Park ◽  
Kyung-Hyeon Yoo ◽  
Seog-Young Yoon ◽  
Woo-Sung Son ◽  
Yong-Il Kim

2-methacryloyloxyethyl phosphorylcholine (MPC) is known to have antibacterial and protein-repellent effects, whereas mesoporous bioactive glass nanoparticles (MBN) are known to have remineralisation effects. We evaluated the antibacterial and remineralisation effects of mixing MPC and MBN at various ratios with orthodontic bonding agents. MPC and MBN were mixed in the following weight percentages in CharmFil-Flow (CF): CF, 3% MPC, 5% MPC, 3% MPC + 3% MBN, and 3% MPC + 5% MBN. As the content of MPC and MBN increased, the mechanical properties of the resin decreased. At 5% MPC, the mechanical properties decreased significantly with respect to CF (shear bond strength), gelation of MPC occurred, and no significant difference was observed in terms of protein adsorption compared to the control group. Composition 3% MPC + 5% MBN exhibited the lowest protein adsorption because the proportion of hydrophobic resin composite decreased; CF (91.8 ± 4.8 μg/mL), 3% MPC (73.9 ± 2.6 μg/mL), 3% MPC + 3% MBN (69.4 ± 3.6 μg/mL), and 3% MPC + 5% MBN (55.9 ± 1.6 μg/mL). In experiments against S. mutans and E. coli, addition of MPC and MBN resulted in significant antibacterial effects. In another experiment, the anti-demineralisation effect was improved when MPC was added, and when MBN was additionally added, it resulted in a synergetic effect. When MPC and MBN were added at an appropriate ratio to the orthodontic bonding agents, the protein-repellent, antibacterial, and anti-demineralisation effects were improved. This combination could thus be an alternative way of treating white spot lesions.


Materials ◽  
2021 ◽  
Vol 14 (10) ◽  
pp. 2611
Author(s):  
Danijela Marovic ◽  
Håvard J. Haugen ◽  
Visnja Negovetic Mandic ◽  
Matej Par ◽  
Kai Zheng ◽  
...  

Experimental dental resin composites incorporating copper-doped mesoporous bioactive glass nanospheres (Cu-MBGN) were designed to impart antibacterial and remineralizing properties. The study evaluated the influence of Cu-MBGN on the mechanical properties and photopolymerization of resin composites. Cu-MBGN were synthesized using a microemulsion-assisted sol–gel method. Increasing amounts of Cu-MBGN (0, 1, 5, and 10 wt %) were added to the organic polymer matrix with inert glass micro- and nanofillers while maintaining a constant resin/filler ratio. Six tests were performed: X-ray diffraction, scanning electron microscopy, flexural strength (FS), flexural modulus (FM), Vickers microhardness (MH), and degree of conversion (DC). FS and MH of Cu-MBGN composites with silica fillers showed no deterioration with aging, with statistically similar results at 1 and 28 days. FM was not influenced by the addition of Cu-MBGN but was reduced for all tested materials after 28 days. The specimens with 1 and 5% Cu-MBGN had the highest FS, FM, MH, and DC values at 28 days, while controls with 45S5 bioactive glass had the lowest FM, FS, and MH. DC was high for all materials (83.7–93.0%). Cu-MBGN composites with silica have a potential for clinical implementation due to high DC and good mechanical properties with adequate resistance to aging.


RSC Advances ◽  
2020 ◽  
Vol 10 (73) ◽  
pp. 44835-44840
Author(s):  
Xiang Qin ◽  
Rong Cao ◽  
Jingjing Zheng ◽  
Guojun Shi ◽  
Lijun Ji ◽  
...  

A new strategy for preparing mesoporous metal-doped bioactive glass fibers.


2019 ◽  
Vol 103 ◽  
pp. 109764 ◽  
Author(s):  
Kai Zheng ◽  
Preethi Balasubramanian ◽  
Thomas E. Paterson ◽  
Rene Stein ◽  
Sheila MacNeil ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document