High-efficiency and safe sulfur-doped iron oxides for magnetic resonance imaging-guided photothermal/magnetic hyperthermia therapy

2020 ◽  
Vol 49 (17) ◽  
pp. 5493-5502
Author(s):  
Guoqiang Guan ◽  
Bo Li ◽  
Wenlong Zhang ◽  
Zhe Cui ◽  
Shu-Ang He ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Iron Oxides ◽  
High Efficiency ◽  
Magnetic Hyperthermia ◽  
Resonance Imaging ◽  
Highly Efficient ◽  
Hyperthermia Therapy ◽  
Body Clearance

Highly efficient body-clearance sulfur-doped iron oxides were developed for magnetic resonance imaging-guided photo-magnetic hyperthermia therapy.

scholarly journals Tumor growth analysis by magnetic resonance imaging of the C6 glioblastoma model with prospects for the assessment of magnetohyperthermia therapy

2012 ◽  
Vol 10 (1) ◽  
pp. 11-15 ◽  
Author(s):  
André César da Silva ◽  
Francisco Romero Cabral ◽  
Javier Bustamante Mamani ◽  
Jackeline Moraes Malheiros ◽  
Roberson Saraiva Polli ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Tumor Growth ◽  
Wistar Rats ◽  
Culture Medium ◽  
Tumor Volume ◽  
Magnetic Hyperthermia ◽  
Resonance Imaging ◽  
Hyperthermia Therapy ◽  
Spin Echo Sequence

OBJECTIVE: The objective was to establish a pattern of tumor growth of the C6 model of glioblastoma multiform in Wistar rats via magnetic resonance imaging (MRI) for the subsequent verification of tumor volume reduction due to magnetic hyperthermia therapy. METHODS: Young male Wistar rats weighing between 250 and 300 g were used for the C6 model. After the rates were anesthetized (55 mg/kg ketamine and 11 mg/kg xylazine), C6 lineage tumorigenic cells suspended in culture medium (10(5) cells in 10 µl) were stereotaxically injected into the right frontal cortex (bregma coordinates: 2.0 mm anteroposterior, 3.0 mm laterolateral, and 2.5 mm depth) of the rats using a Hamilton syringe. For the control group, the rats were injected with culture medium without cells. MRI scans were performed at 14, 21, and 28 d after the injection using a 2.0 T MRI scanner (Bruker BioSpec, Germany). The animals were anesthetized with 55 mg/kg ketamine and 11 mg/kg xylazine before being examined. Coronal multilayers were acquired using a standard spin echo sequence with the following parameters: repetition/echo time = 4.000 ms/67.1 ms, field of view = 3.50, matrix = 192, slice thickness = 0.4 mm, and slice separation = 0 mm. RESULTS: The MRI analysis enabled a clear visualization of the tumor mass, and it was possible to establish the tumor volume parameters on the various days that were examined. The volume at 14 d after induction was 13.7 ± 2.5 mm³. On days 21 and 28, the tumor volumes were 31.7 ± 6.5 mm³ and 122.1 ± 11.8 mm³, respectively. CONCLUSION: These results demonstrated that it is possible to evaluate the C6 model tumor volume in rats, which will allow for the future implementation and verification of magnetic hyperthermia therapy.

“Transformed” Fe3S4 tetragonal nanosheets: a high-efficiency and body-clearable agent for magnetic resonance imaging guided photothermal and chemodynamic synergistic therapy

Nanoscale ◽  
2018 ◽  
Vol 10 (37) ◽  
pp. 17902-17911 ◽  
Author(s):  
Guoqiang Guan ◽  
Xin Wang ◽  
Bo Li ◽  
Wenlong Zhang ◽  
Zhe Cui ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Side Effects ◽  
Magnetic Resonance ◽  
High Efficiency ◽  
Resonance Imaging ◽  
Body Clearance

The PVP coated Fe3S4 tetragonal nanosheets could be employed to realize magnetic resonance imaging guided photothermal/chemodynamic therapy and body-clearance without appreciable toxic side effects.

Porous cobalt sulfide hollow nanospheres with tunable optical property for magnetic resonance imaging-guided photothermal therapy

Nanoscale ◽  
2018 ◽  
Vol 10 (29) ◽  
pp. 14190-14200 ◽  
Author(s):  
Guoqiang Guan ◽  
Xin Wang ◽  
Xiaojuan Huang ◽  
Wenlong Zhang ◽  
Zhe Cui ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Optical Property ◽  
Magnetic Resonance ◽  
Photothermal Therapy ◽  
Cobalt Sulfide ◽  
Resonance Imaging ◽  
Hollow Nanospheres ◽  
Highly Efficient ◽  
Tunable Absorption

Simple, highly efficient, and safe porous cobalt sulfide hollow nanospheres with tunable absorption as a magnetic resonance imaging-guided photothermal theranostic platform.

High-efficiency laser-pumping system for magnetic resonance imaging

2000 ◽  
Author(s):  
Marziale Milani ◽  
Guido Baroni ◽  
Lorenzo Ferraro ◽  
P. Sozzani ◽  
Massimo Adobati ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Efficiency ◽  
Resonance Imaging ◽  
Pumping System ◽  
Laser Pumping
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