Direct enantioselective allylic substitution of 4-hydroxycoumarin derivatives with branched allylic alcohols via iridium catalysis

2020 ◽  
Vol 56 (60) ◽  
pp. 8404-8407
Author(s):  
Ruigang Xu ◽  
Kai Li ◽  
Jiaqi Wang ◽  
Jiamin Lu ◽  
Lina Pan ◽  
...  
Keyword(s):  
Substitution Reaction ◽  
Allylic Alcohols ◽  
Allylic Substitution ◽  
Iridium Catalysis ◽  
High Yields

An iridium catalysed direct asymmetric allylic substitution reaction of 4-hydroxycoumarin derivatives with allylic alcohols with remarkably high yields and excellent enantioselectivities was realized.

Palladium-Catalyzed Allylic Substitution Reaction of Benzothiazolylacetamide with Allylic Alcohols in Water

2019 ◽  
Vol 84 (16) ◽  
pp. 10111-10119 ◽  
Author(s):  
Shulei Pan ◽  
Binqiang Wu ◽  
Jinjin Hu ◽  
Ruigang Xu ◽  
Min Jiang ◽  
...  
Keyword(s):  
Substitution Reaction ◽  
Allylic Alcohols ◽  
Allylic Substitution ◽  
Palladium Catalyzed

Palladium Catalyzed Controllable Mono‐ or Di‐Allylic Substitution Reaction of Benzothiazolylacetate with Allylic Alcohols

2019 ◽  
Vol 361 (6) ◽  
pp. 1322-1334 ◽  
Author(s):  
Peipei Yan ◽  
Shulei Pan ◽  
Jinjin Hu ◽  
Limei Lu ◽  
Xiaofei Zeng ◽  
...  
Keyword(s):  
Substitution Reaction ◽  
Allylic Alcohols ◽  
Allylic Substitution ◽  
Palladium Catalyzed

Catalytic Asymmetric Substitution Reaction of 3-Substituted 2-Indolylmethanols with 2-Naphthols

Synthesis ◽  
2020 ◽  
Vol 52 (23) ◽  
pp. 3684-3692
Author(s):  
Feng Gao ◽  
Yu-Chen Zhang ◽  
Feng Shi ◽  
Jin-Ping Lan ◽  
Yi-Nan Lu ◽  
...  
Keyword(s):  
Phosphoric Acid ◽  
Substitution Reaction ◽  
Enantioselective Synthesis ◽  
Chiral Phosphoric Acid ◽  
Catalytic Asymmetric ◽  
High Yields

A catalytic asymmetric substitution of 3-substituted 2-indolylmethanols with 2-naphthols has been established under the catalysis of chiral phosphoric acid. By this approach, a series of structurally diversified triarylmethane derivatives were obtained in moderate to high yields with good enantioselectivities (up to 97% yield, 95:5 er). This approach not only enriches the chemistry of 2-indolylmethanol-inolved catalytic asymmetric substitutions, but also provides a useful method for the enantioselective synthesis of chiral triarylmethane derivatives.

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