Smurf1-targeting miR-19b-3p-modified BMSCs combined PLLA composite scaffold to enhance osteogenic activity and treat critical-sized bone defects

2020 ◽  
Vol 8 (21) ◽  
pp. 6069-6081
Author(s):  
Ao Xiong ◽  
Yijun He ◽  
Liang Gao ◽  
Guoqing Li ◽  
Jian Weng ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Composite Scaffold ◽  
Biological Materials ◽  
Bone Defects ◽  
Engineering Technology ◽  
Osteogenic Activity ◽  
The Past ◽  
Seed Cells ◽  
Tissue Engineering Technology

Over the past few years, tissue-engineering technology provided a new direction for bone defects therapy, which involved developing applicable biological materials composite with seed cells to repair bone defects tissue.

DEVELOPMENTAL STATUS AND PERSPECTIVES FOR TISSUE ENGINEERING IN UROLOGY

2021 ◽  
Vol 12 (07) ◽  
pp. 5-13
Author(s):  
Elcin Nizami Huseyn ◽  
Keyword(s):  
Tissue Engineering ◽  
Biological Materials ◽  
Organ Damage ◽  
Biological Tissues ◽  
Tissue Cell ◽  
Sperm Cells ◽  
Engineering Technology ◽  
The Future ◽  
Tissue Engineering Technology

Tissue engineering technology and tissue cell-based stem cell research have made great strides in treating tissue and organ damage, correcting tissue and organ dysfunction, and reducing surgical complications. In the past, traditional methods have used biological substitutes for tissue repair materials, while tissue engineering technology has focused on merging sperm cells with biological materials to form biological tissues with the same structure and function as their own tissues. The advantage is that tissue engineering technology can overcome donors. Material procurement restrictions can effectively reduce complications. The aim of studying tissue engineering technology is to find sperm cells and suitable biological materials to replace the original biological functions of tissues and to establish a suitable in vivo microenvironment. This article mainly describes the current developments of tissue engineering in various fields of urology and discusses the future trends of tissue engineering technology in the treatment of complex diseases of the urinary system. The results of the research in this article indicate that while the current clinical studies are relatively few, the good results from existing animal model studies indicate good prospects of tissue engineering technology for the treatment of various urinary tract diseases in the future. Key words: Tissue engineering, kidney, ureter, bladder, urethra

scholarly journals Tissue Engineering in Stomatology: A Review of Potential Approaches for Oral Disease Treatments

2021 ◽  
Vol 9 ◽  
Author(s):  
Lilan Cao ◽  
Huiying Su ◽  
Mengying Si ◽  
Jing Xu ◽  
Xin Chang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Defects ◽  
Clinical Applications ◽  
Artificial Organs ◽  
Oral Disease ◽  
Engineering Technology ◽  
New Approach ◽  
Tissue Engineering Technology

Tissue engineering is an emerging discipline that combines engineering and life sciences. It can construct functional biological structures in vivo or in vitro to replace native tissues or organs and minimize serious shortages of donor organs during tissue and organ reconstruction or transplantation. Organ transplantation has achieved success by using the tissue-engineered heart, liver, kidney, and other artificial organs, and the emergence of tissue-engineered bone also provides a new approach for the healing of human bone defects. In recent years, tissue engineering technology has gradually become an important technical method for dentistry research, and its application in stomatology-related research has also obtained impressive achievements. The purpose of this review is to summarize the research advances of tissue engineering and its application in stomatology. These aspects include tooth, periodontal, dental implant, cleft palate, oral and maxillofacial skin or mucosa, and oral and maxillofacial bone tissue engineering. In addition, this article also summarizes the commonly used cells, scaffolds, and growth factors in stomatology and discusses the limitations of tissue engineering in stomatology from the perspective of cells, scaffolds, and clinical applications.

scholarly journals Biofunctionalization of decellularized porcine aortic valve with OPG-loaded PCL nanoparticles for anti-calcification

RSC Advances ◽  
2019 ◽  
Vol 9 (21) ◽  
pp. 11882-11893
Author(s):  
Yang Li ◽  
Yu Zhang ◽  
Jing-Li Ding ◽  
Ji-Chun Liu ◽  
Jian-Jun Xu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Controlled Release ◽  
Aortic Valve ◽  
Drug Loading ◽  
Biological Factor ◽  
Engineering Technology ◽  
Loading System ◽  
Tissue Engineering Technology

A novel composite valve with controlled release OPG was prepared by introducing tissue engineering technology and nano drug-loading system to introduce anti-calcification biological factor OPG on the decellularized valve.

scholarly journals A Bibliometric Review of Artificial Extracellular Matrices Based on Tissue Engineering Technology Literature: 1990 through 2019

Materials ◽  
2020 ◽  
Vol 13 (13) ◽  
pp. 2891
Author(s):  
Pilar Simmons ◽  
Taylor McElroy ◽  
Antiño R. Allen
Keyword(s):  
Tissue Engineering ◽  
Therapeutic Option ◽  
Extracellular Matrices ◽  
Engineering Technology ◽  
Network Analyses ◽  
Bibliometric Review ◽  
Artificial Extracellular Matrix ◽  
Tissue Engineering Technology

Artificial extracellular matrices (aECMs) are an extension of biomaterials that were developed as in-vitro model environments for tissue cells that mimic the native in vivo target tissues’ structure. This bibliometric analysis evaluated the research productivity regarding aECM based on tissue engineering technology. The Web of Science citation index was examined for articles published from 1990 through 2019 using three distinct aECM-related topic sets. Data were also visualized using network analyses (VOSviewer). Terms related to in-vitro, scaffolds, collagen, hydrogels, and differentiation were reoccurring in the aECM-related literature over time. Publications with terms related to a clinical direction (wound healing, stem cells, artificial skin, in-vivo, and bone regeneration) have steadily increased, as have the number of countries and institutions involved in the artificial extracellular matrix. As progress with 3D scaffolds continues to advance, it will become the most promising technology to provide a therapeutic option to repair or replace damaged tissue.

scholarly journals Translating tissue engineering technology platforms into cancer research

2009 ◽  
Vol 13 (8a) ◽  
pp. 1417-1427 ◽  
Author(s):  
Dietmar W. Hutmacher ◽  
Raymund E. Horch ◽  
Daniela Loessner ◽  
Simone Rizzi ◽  
Shirly Sieh ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cancer Research ◽  
Engineering Technology ◽  
Technology Platforms ◽  
Tissue Engineering Technology

scholarly journals Scaffold strategies combined with mesenchymal stem cells in vaginal construction: a review

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Nicole Andréa Corbellini Henckes ◽  
Dalana Faleiro ◽  
Laura Chao Chuang ◽  
Elizabeth Obino Cirne-Lima
Keyword(s):  
Tissue Engineering ◽  
Mechanical Support ◽  
Vaginal Reconstruction ◽  
Engineering Technology ◽  
Cell Based Therapy ◽  
Tissue Reconstruction ◽  
New Treatment ◽  
Traditional Approaches ◽  
Treatment Alternatives ◽  
Tissue Engineering Technology

AbstractTissue engineering has provided new treatment alternatives for tissue reconstruction. Advances in the tissue engineering field have resulted in mechanical support and biological substitutes to restore, maintain or improve tissue/organs structures and functions. The application of tissue engineering technology in the vaginal reconstruction treatment can not only provide mechanical requirements, but also offer tissue repairing as an alternative to traditional approaches. In this review, we discuss recent advances in cell-based therapy in combination with scaffolds strategies that can potentially be adopted for gynaecological transplantation.

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