Cu2+-Regulated reversible coordination interaction of GQD@Tb/GMP ICP nanoparticles: towards directly monitoring cerebrospinal acetylcholinesterase as a biomarker for cholinic brain dysfunction

The Analyst ◽  
2020 ◽  
Vol 145 (24) ◽  
pp. 7849-7857
Author(s):  
Chang Liu ◽  
Chunyu Huang ◽  
Ruixue Ma ◽  
Wanying Zhai ◽  
Jingjing Deng ◽  
...  
Keyword(s):  
Rational Design ◽  
Brain Dysfunction ◽  
Coordination Interaction ◽  
Related Disease ◽  
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Based on the rational design of the Cu2+-regulated reversible coordination interaction of GQD@Tb/GMP ICPs, a new turn-on fluorescence strategy is developed for monitoring AChE in CSF as a biomarker for cholinic brain dysfunction-related disease.

scholarly journals Rational design of aggregation-induced emission sensor based on Rhodamine B for turn-on sensing of trivalent metal cations, reversible data protection, and bioimaging

2019 ◽  
Vol 3 (1) ◽  
pp. 151-160 ◽  
Author(s):  
Hai-Xia Yu ◽  
Junge Zhi ◽  
Zheng-Feng Chang ◽  
Tianjiao Shen ◽  
Wei-Lu Ding ◽  
...  
Keyword(s):  
Rhodamine B ◽  
Data Protection ◽  
Rational Design ◽  
Thiophene Ring ◽  
Metal Cations ◽  
Trivalent Metal ◽  
Active Molecule ◽  
Aggregation Induced Emission ◽  
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A novel AIE-active molecule (TPEThRB) composed of a tetraphenylethene unit as a AIE factor, Rhodamine spirolactam as a receptor, and thiophene ring as a conjugated electron-rich linker was obtained.

Rational design of a turn-on fluorescent sensor for α-ketoglutaric acid in a microfluidic chip

2014 ◽  
Vol 5 (10) ◽  
pp. 4012-4016 ◽  
Author(s):  
Pengwei Jin ◽  
Changhong Jiao ◽  
Zhiqian Guo ◽  
Ye He ◽  
Shiqin Zhu ◽  
...  
Keyword(s):  
High Throughput ◽  
Microfluidic Chip ◽  
High Throughput Screening ◽  
Rational Design ◽  
Fluorescent Sensor ◽  
Fluorescent Chemosensors ◽  
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A rational design of turn-on fluorescent chemosensors for monitoring α-ketoglutaric acid has been developed with a microfluidic chip, indicative of a potential platform for high-throughput screening and monitoring of kinetics, especially in biological fields.

Rational design of a fast and selective near-infrared fluorescent probe for targeted monitoring of endogenous nitric oxide

2017 ◽  
Vol 53 (76) ◽  
pp. 10520-10523 ◽  
Author(s):  
Junma Tang ◽  
Zhiqian Guo ◽  
Yutao Zhang ◽  
Bing Bai ◽  
Wei-Hong Zhu
Keyword(s):  
Nitric Oxide ◽  
Fluorescent Probe ◽  
Rational Design ◽  
Near Infrared ◽  
High Specificity ◽  
Fast Response ◽  
Turn On ◽  
Endogenous Nitric Oxide

We developed a fast and selective near-infrared (NIR) fluorescent probe for the targeted tracing of endogenous NO which possesses vital features including a significant turn-on NIR response, high specificity, and a fast response.

Rational design of a highly sensitive and selective “turn-on” fluorescent sensor for PO43− detection

2015 ◽  
Vol 44 (48) ◽  
pp. 20830-20833 ◽  
Author(s):  
Si-Quan Jiang ◽  
Zi-Yan Zhou ◽  
Shu-Ping Zhuo ◽  
Guo-Gang Shan ◽  
Ling-Bao Xing ◽  
...  
Keyword(s):  
Schiff Base ◽  
Rational Design ◽  
Fluorescent Sensor ◽  
Turn On ◽  
Base Unit ◽  
Highly Sensitive

An in situ-generated iron(iii) complex with a 1,8-naphthalene-based Schiff base unit has been rationally designed, which exhibits a highly selective response and excellent sensitivity for the turn-on detection of PO43− anions.

Rational design of an HClO-specific triggered self-immolative fluorescent turn-on sensor and its bioimaging applications

2021 ◽  
Author(s):  
Xiao-Bo Wang ◽  
Dalong Zhang ◽  
Hui-Jing Li ◽  
Xuhao Lu ◽  
Quanze Liu ◽  
...  
Keyword(s):  
Small Molecule ◽  
Rational Design ◽  
Turn On ◽  
Intuitive Method

The development of a rapid and intuitive method for the detection of a specific small molecule biomarker is important for understanding the pathogenesis of relevant diseases. Described here is the...

Rational Design of a Fluorescence-Turn-On Sensor Array for Phosphates in Blood Serum

2007 ◽  
Vol 119 (41) ◽  
pp. 7995-7998 ◽  
Author(s):  
Grigory V. Zyryanov ◽  
Manuel A. Palacios ◽  
Pavel Anzenbacher
Keyword(s):  
Blood Serum ◽  
Rational Design ◽  
Sensor Array ◽  
Turn On ◽  
Fluorescence Turn On
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