Rational Design of “Turn-On” Allosteric DNAzyme Catalytic Beacons for Aqueous Mercury Ions with Ultrahigh Sensitivity and Selectivity

2007 ◽  
Vol 119 (40) ◽  
pp. 7731-7734 ◽  
Author(s):  
Juewen Liu ◽  
Yi Lu
Sensor Review ◽  
2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Mulayam Singh Gaur ◽  
Rajni Yadav ◽  
Mamta Kushwah ◽  
Anna Nikolaevna Berlina

Purpose This information will be useful in the selection of materials and technology for the detection and removal of mercury ions at a low cost and with high sensitivity and selectivity. The purpose of this study is to provide the useful information for selection of materials and technology to detect and remove the mercury ions from water with high sensitivity and selectivity. The purpose of this study is to provide the useful information for selection of materials and technology to detect and remove the mercury ions from water with high sensitivity and selectivity. Design/methodology/approach Different nano- and bio-materials allowed for the development of a variety of biosensors – colorimetric, chemiluminescent, electrochemical, whole-cell and aptasensors – are described. The materials used for their development also make it possible to use them in removing heavy metals, which are toxic contaminants, from environmental water samples. Findings This review focuses on different technologies, tools and materials for mercury (heavy metals) detection and remediation to environmental samples. Originality/value This review gives up-to-date and systemic information on modern nanotechnology methods for heavy metal detection. Different recognition molecules and nanomaterials have been discussed for remediation to water samples. The present review may provide valuable information to researchers regarding novel mercury ions detection sensors and encourage them for further research/development.


Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2889 ◽  
Author(s):  
Ye Teng ◽  
Hisae Tateishi-Karimata ◽  
Takaaki Tsuruoka ◽  
Naoki Sugimoto

Nucleic acid stability and structure, which are crucial to the properties of fluorescent DNA-templated silver nanoclusters (DNA-Ag NCs), significantly change in ionic liquids. In this work, our purpose was to study DNA-Ag NCs in a buffer containing the hydrated ionic liquid of choline dihydrogen phosphate (choline dhp) to improve fluorescence for application in DNA detection. Due to the stabilisation of an i-motif structure by the choline cation, a unique fluorescence emission—that was not seen in an aqueous buffer—was observed in choline dhp and remained stable for more than 30 days. A DNA-Ag NCs probe was designed to have greater fluorescence intensity in choline dhp in the presence of a target DNA. A turn-on sensing platform in choline dhp was built for the detection of the BRCA1 gene, which is related to familial breast and ovarian cancers. This platform showed better sensitivity and selectivity in distinguishing a target sequence from a mutant sequence in choline dhp than in the aqueous buffer. Our study provides new evidence regarding the effects of structure on properties of fluorescent DNA-Ag NCs and expands the applications of fluorescent DNA-Ag NCs in an ionic liquid because of improved sensitivity and selectivity.


2017 ◽  
Vol 5 (38) ◽  
pp. 9943-9951 ◽  
Author(s):  
Xubin Zheng ◽  
Ruiqing Fan ◽  
Yang Song ◽  
Ani Wang ◽  
Kai Xing ◽  
...  

A novel probe, designed and prepared through PSM of Cu-MOFs and Tb3+ions, shows high sensitivity and selectivity for H2S.


2019 ◽  
Vol 3 (1) ◽  
pp. 151-160 ◽  
Author(s):  
Hai-Xia Yu ◽  
Junge Zhi ◽  
Zheng-Feng Chang ◽  
Tianjiao Shen ◽  
Wei-Lu Ding ◽  
...  

A novel AIE-active molecule (TPEThRB) composed of a tetraphenylethene unit as a AIE factor, Rhodamine spirolactam as a receptor, and thiophene ring as a conjugated electron-rich linker was obtained.


2020 ◽  
Vol 44 (44) ◽  
pp. 19155-19165
Author(s):  
Burcu Aydıner ◽  
Ömer Şahin ◽  
Deniz Çakmaz ◽  
Gökhan Kaplan ◽  
Kerem Kaya ◽  
...  

Novel 7-diethylaminocoumarin based dyes showed high sensitivity and selectivity to cyanide anions in both organic and aqueous solutions, which was observed by a drastic increment in the emission intensity.


2019 ◽  
Vol 48 (38) ◽  
pp. 14408-14417 ◽  
Author(s):  
Xubin Zheng ◽  
Ruiqing Fan ◽  
Haoyang Lu ◽  
Bowen Wang ◽  
Jingkun Wu ◽  
...  

A fluorescent probe designed and prepared through postsynthetic modification (PSM) showed high sensitivity and selectivity for N-methylformamide (NMF) in urine and methylglyoxal (MGO) in serum.


2011 ◽  
Vol 239-242 ◽  
pp. 934-939
Author(s):  
Hui Xu ◽  
Shuli Gao ◽  
Jian Nong Chen ◽  
Quan Wen Liu

We report a label-free, fast, fluorescence turn on assay for Hg2+detecton by using mercury-specific DNA (MSD), Sybr Green I (SG) and gold nanoparticles (AuNPs). SG efficiently discriminates MSD and MSD/Hg2+complex. The addition of gold nanoparticle decreases the background fluorescence signal further for MSD. The fluorescence intensity of MSD/Hg2+complex keeps constant after addition of AuNPs. This property improves the signal-to-background ratio and decreases the detection limitation further. In addition, the method shows improved selectivity compared with that in the absence of AuNPs. This strategy could be applied to the detection of potassium ions and showed good generality.


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